DE69529418T2 - Cyclopropachromencarbonsäure derivate - Google Patents
Cyclopropachromencarbonsäure derivateInfo
- Publication number
- DE69529418T2 DE69529418T2 DE69529418T DE69529418T DE69529418T2 DE 69529418 T2 DE69529418 T2 DE 69529418T2 DE 69529418 T DE69529418 T DE 69529418T DE 69529418 T DE69529418 T DE 69529418T DE 69529418 T2 DE69529418 T2 DE 69529418T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- carbon atoms
- substituted
- hydrogen atom
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25646894 | 1994-10-21 | ||
JP22536595A JP3993651B2 (ja) | 1994-10-21 | 1995-09-01 | シクロプロパクロメンカルボン酸誘導体 |
PCT/JP1995/002163 WO1996012715A1 (fr) | 1994-10-21 | 1995-10-20 | Derives de cyclopropachromenecarboxylate |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69529418D1 DE69529418D1 (de) | 2003-02-20 |
DE69529418T2 true DE69529418T2 (de) | 2003-08-14 |
Family
ID=26526593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69529418T Expired - Lifetime DE69529418T2 (de) | 1994-10-21 | 1995-10-20 | Cyclopropachromencarbonsäure derivate |
Country Status (7)
Country | Link |
---|---|
US (1) | US5843988A (de) |
EP (1) | EP0787723B1 (de) |
JP (1) | JP3993651B2 (de) |
AT (1) | ATE231142T1 (de) |
DE (1) | DE69529418T2 (de) |
ES (1) | ES2191063T3 (de) |
WO (1) | WO1996012715A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19801646A1 (de) * | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte alpha,beta-annellierte Butyrolactone |
DE19801647A1 (de) | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte beta,gamma-annellierte Lactone |
DE19801636A1 (de) | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte bicyclische Lactone |
EP1059090A4 (de) * | 1998-03-03 | 2002-02-27 | Yamanouchi Pharma Co Ltd | Medikamente gegen hirninfarkt. |
GB9823845D0 (en) * | 1998-11-02 | 1998-12-23 | Lilly Co Eli | Pharmaceutical compounds |
AU2241400A (en) | 1999-04-06 | 2000-10-12 | Yamanouchi Pharmaceutical Co., Ltd. | Novel thiazolobenzoimidazole derivative |
GB0007193D0 (en) * | 2000-03-25 | 2000-05-17 | Univ Manchester | Treatment of movrmrnt disorders |
US6660858B2 (en) * | 2001-03-28 | 2003-12-09 | Lion Bioscience Ag | 2-aminobenzoxazole derivatives and combinatorial libraries thereof |
WO2005007096A2 (en) * | 2003-07-11 | 2005-01-27 | Merck & Co., Inc. | Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator |
CN101862322A (zh) | 2004-07-30 | 2010-10-20 | 托伦特药物有限公司 | 奈必洛尔及其药学可接受盐、制备方法以及奈必洛尔的药物组合物 |
DE102005011534A1 (de) * | 2005-03-10 | 2006-09-21 | Merck Patent Gmbh | Chromen-4-on-Derivate |
EP2275096A3 (de) | 2005-08-26 | 2011-07-13 | Braincells, Inc. | Neurogenese durch modulation des Muscarinrezeptors |
EP2258357A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese mit Acetylcholinesterasehemmer |
WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
DE102005062990A1 (de) * | 2005-12-28 | 2007-07-05 | Grünenthal GmbH | Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
AU2007249435A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | アンジオテンシン調節による神経新生 |
KR20090064418A (ko) * | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
DK2493871T3 (da) | 2009-10-30 | 2014-11-10 | Prestwick Chemical Sas | Nye oximderivater samt deres anvendelse som allosteriske modulatorer af metabotropiske glutamatreceptorer |
ES2714073T3 (es) * | 2014-08-27 | 2019-05-27 | Prexton Therapeutics Sa | Nuevo derivado de oxima de cromona y su uso como modulador alostérico de receptores metabotrópicos del glutamato |
TN2018000061A1 (en) | 2015-08-27 | 2019-07-08 | Prexton Therapeutics Sa | Brain-penetrant chromone oxime derivative for the therapy of levodopa-induced dyskinesia |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0723367B2 (ja) * | 1986-02-27 | 1995-03-15 | サントリー株式会社 | オキサビシクロヘプタン誘導体 |
CA2037188A1 (en) * | 1990-06-06 | 1991-12-07 | Toshio Tatsuoka | Agent for treating disorders from cerebral neuro-degeneration |
JP3054207B2 (ja) * | 1990-06-06 | 2000-06-19 | サントリー株式会社 | シクロプロパクロメン誘導体 |
DE4018468A1 (de) * | 1990-06-08 | 1991-12-12 | Ultrakust Electronic Gmbh | Verfahren und vorrichtung zur entnahme einer repraesentativen milchprobe |
-
1995
- 1995-09-01 JP JP22536595A patent/JP3993651B2/ja not_active Expired - Fee Related
- 1995-10-20 WO PCT/JP1995/002163 patent/WO1996012715A1/ja active IP Right Grant
- 1995-10-20 ES ES95934860T patent/ES2191063T3/es not_active Expired - Lifetime
- 1995-10-20 DE DE69529418T patent/DE69529418T2/de not_active Expired - Lifetime
- 1995-10-20 EP EP95934860A patent/EP0787723B1/de not_active Expired - Lifetime
- 1995-10-20 AT AT95934860T patent/ATE231142T1/de not_active IP Right Cessation
- 1995-10-20 US US08/817,389 patent/US5843988A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0787723B1 (de) | 2003-01-15 |
ATE231142T1 (de) | 2003-02-15 |
US5843988A (en) | 1998-12-01 |
WO1996012715A1 (fr) | 1996-05-02 |
JPH08169884A (ja) | 1996-07-02 |
JP3993651B2 (ja) | 2007-10-17 |
EP0787723A1 (de) | 1997-08-06 |
EP0787723A4 (de) | 1998-02-04 |
DE69529418D1 (de) | 2003-02-20 |
ES2191063T3 (es) | 2003-09-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: DAIICHI SUNTORY PHARMA CO., LTD., TOKIO/TOKYO, JP |
|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DAIICHI ASUBIO PHARMA CO., LTD., TOKIO/TOKYO, JP |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: ASUBIO PHARMA CO., LTD., TOKYO, JP |