DE69521223T2 - 6-Azaindole-Hemmer der Tromboxan-Synthetase - Google Patents
6-Azaindole-Hemmer der Tromboxan-SynthetaseInfo
- Publication number
- DE69521223T2 DE69521223T2 DE69521223T DE69521223T DE69521223T2 DE 69521223 T2 DE69521223 T2 DE 69521223T2 DE 69521223 T DE69521223 T DE 69521223T DE 69521223 T DE69521223 T DE 69521223T DE 69521223 T2 DE69521223 T2 DE 69521223T2
- Authority
- DE
- Germany
- Prior art keywords
- tromboxane
- synthetase
- azaindole
- integer
- zero
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/189,212 US5468757A (en) | 1994-01-31 | 1994-01-31 | 6-azaindole thromboxane synthase inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69521223D1 DE69521223D1 (de) | 2001-07-19 |
DE69521223T2 true DE69521223T2 (de) | 2001-11-08 |
Family
ID=22696403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69521223T Expired - Fee Related DE69521223T2 (de) | 1994-01-31 | 1995-01-30 | 6-Azaindole-Hemmer der Tromboxan-Synthetase |
Country Status (11)
Country | Link |
---|---|
US (1) | US5468757A (de) |
EP (1) | EP0668279B1 (de) |
JP (1) | JPH0853448A (de) |
AT (1) | ATE202103T1 (de) |
CA (1) | CA2141231A1 (de) |
DE (1) | DE69521223T2 (de) |
DK (1) | DK0668279T3 (de) |
ES (1) | ES2157292T3 (de) |
GR (1) | GR3036570T3 (de) |
PT (1) | PT668279E (de) |
SI (1) | SI0668279T1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2677910C (en) * | 1997-10-17 | 2011-03-15 | Ark Therapeutics Limited | The use of inhibitors of the renin-angiotensin system for the treatment of cardiovascular diseases |
CN1279682A (zh) | 1997-10-20 | 2001-01-10 | 霍夫曼-拉罗奇有限公司 | 双环激酶抑制剂 |
ES2213984T3 (es) | 1998-10-30 | 2004-09-01 | Eli Lilly And Company | Derivados de azaindol y su uso como agentes antitrombicos. |
AU3395000A (en) * | 1999-03-10 | 2000-09-28 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
US20040235867A1 (en) * | 2001-07-24 | 2004-11-25 | Bilodeau Mark T. | Tyrosine kinase inhibitors |
GB0330043D0 (en) * | 2003-12-24 | 2004-01-28 | Pharmacia Italia Spa | Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them |
PE20060430A1 (es) | 2004-06-09 | 2006-05-25 | Glaxo Group Ltd | Derivados de pirrolopiridina como moduladores de los receptores cannabinoides |
US20070155738A1 (en) | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
CN112839648A (zh) * | 2018-06-07 | 2021-05-25 | 达萨玛治疗公司 | Sarm1抑制剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1250844A (en) * | 1981-06-22 | 1989-03-07 | Neville Ford | Substituted imidazo¬1,5-a|pyridines, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application |
US4588732A (en) * | 1982-12-21 | 1986-05-13 | Ciba-Geigy Corporation | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors |
US4470986A (en) * | 1982-12-21 | 1984-09-11 | Ciba-Geigy Corporation | Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors |
DE3302125A1 (de) * | 1983-01-22 | 1984-07-26 | Boehringer Ingelheim KG, 6507 Ingelheim | Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung |
FR2658511B1 (fr) * | 1990-02-16 | 1992-06-19 | Union Pharma Scient Appl | Nouveaux derives de benzimidazole et d'azabenzimidazole, antagonistes des recepteurs au thromboxane; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
DE69227561T2 (de) * | 1991-08-21 | 1999-06-02 | Eisai Co Ltd | Kondensierte Pyrimidinderivate als Antitumorverbindungen |
-
1994
- 1994-01-31 US US08/189,212 patent/US5468757A/en not_active Expired - Fee Related
-
1995
- 1995-01-27 CA CA002141231A patent/CA2141231A1/en not_active Abandoned
- 1995-01-30 DE DE69521223T patent/DE69521223T2/de not_active Expired - Fee Related
- 1995-01-30 SI SI9530517T patent/SI0668279T1/xx unknown
- 1995-01-30 DK DK95300551T patent/DK0668279T3/da active
- 1995-01-30 EP EP95300551A patent/EP0668279B1/de not_active Expired - Lifetime
- 1995-01-30 PT PT95300551T patent/PT668279E/pt unknown
- 1995-01-30 ES ES95300551T patent/ES2157292T3/es not_active Expired - Lifetime
- 1995-01-30 AT AT95300551T patent/ATE202103T1/de not_active IP Right Cessation
- 1995-01-31 JP JP7013686A patent/JPH0853448A/ja not_active Withdrawn
-
2001
- 2001-09-07 GR GR20010401424T patent/GR3036570T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0668279B1 (de) | 2001-06-13 |
PT668279E (pt) | 2001-09-28 |
DE69521223D1 (de) | 2001-07-19 |
EP0668279A3 (de) | 1995-08-30 |
ES2157292T3 (es) | 2001-08-16 |
DK0668279T3 (da) | 2001-08-27 |
JPH0853448A (ja) | 1996-02-27 |
EP0668279A2 (de) | 1995-08-23 |
CA2141231A1 (en) | 1995-08-01 |
ATE202103T1 (de) | 2001-06-15 |
GR3036570T3 (en) | 2001-12-31 |
SI0668279T1 (en) | 2001-12-31 |
US5468757A (en) | 1995-11-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |