ES2121036T3 - Derivados de alquilenodiamina. - Google Patents
Derivados de alquilenodiamina.Info
- Publication number
- ES2121036T3 ES2121036T3 ES93111194T ES93111194T ES2121036T3 ES 2121036 T3 ES2121036 T3 ES 2121036T3 ES 93111194 T ES93111194 T ES 93111194T ES 93111194 T ES93111194 T ES 93111194T ES 2121036 T3 ES2121036 T3 ES 2121036T3
- Authority
- ES
- Spain
- Prior art keywords
- integer
- substituted
- derivatives
- alkylen
- diamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Insulating Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE DESCRIBEN NUEVOS DERIVADOS DE ALQUILENODIAMINA DE LA SIGUIENTE FORMULA, QUE SON EFICACES PARA EL TRATAMIENTO DE LA DISURIA: EN LA QUE R1 ES HIDROGENO, ALQUILO O UN GRUPO DE FENIL SUSTITUIDO O NO SUSTITUIDO, NAFTILO, O HETEROCICLICO AROMATICO; R2 FENIL SUSTITUIDO O NO SUSTITUIDO, NAFTILO O UN GRUPO HETEROCICLIDO AROMATICO; R3 Y R4 REPRESENTAN HIDROGENO, ALQUILO, ARALQUILO O ARILO; O R3 Y R4 SE COMBINAN PARA FORMAR UNO DE LOS GRUPOS HETEROCICLICOS EN MIEMBROS SUSTITUIDOS O NO SUSTITUIDOS 5Z ES N ES UN NUMERO ENTERO DE 0
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20971392 | 1992-07-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2121036T3 true ES2121036T3 (es) | 1998-11-16 |
Family
ID=16577418
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93111194T Expired - Lifetime ES2121036T3 (es) | 1992-07-14 | 1993-07-13 | Derivados de alquilenodiamina. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0579169B1 (es) |
JP (1) | JP2866277B2 (es) |
KR (1) | KR100293334B1 (es) |
CN (1) | CN1045597C (es) |
AT (1) | ATE170516T1 (es) |
AU (1) | AU659561B2 (es) |
CA (1) | CA2100376A1 (es) |
DE (1) | DE69320730T2 (es) |
DK (1) | DK0579169T3 (es) |
ES (1) | ES2121036T3 (es) |
FI (1) | FI933206A (es) |
HU (1) | HU221196B1 (es) |
MX (1) | MX9304259A (es) |
NO (1) | NO303827B1 (es) |
PH (1) | PH31474A (es) |
RU (1) | RU2069661C1 (es) |
TW (1) | TW300895B (es) |
ZA (1) | ZA935074B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5773437A (en) * | 1994-03-31 | 1998-06-30 | Nippon Chemiphar Co., Ltd. | Alkylenediamine derivatives |
US5563277A (en) * | 1994-12-21 | 1996-10-08 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
AR057218A1 (es) * | 2005-12-15 | 2007-11-21 | Astra Ab | Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato |
EA201791289A1 (ru) | 2014-12-11 | 2017-12-29 | Президент Энд Феллоуз Оф Гарвард Колледж | Ингибиторы клеточного некроза и связанные с ними способы |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3576808A (en) * | 1967-09-15 | 1971-04-27 | Miles Lab | N-4-phenyl-1-piperazinylalkyl-5-phenyl-oxazolidinones |
JPS6183170A (ja) * | 1984-09-28 | 1986-04-26 | Nippon Chemiphar Co Ltd | 新規な1,3−オキサゾリジン−2−オン誘導体およびその製造法 |
-
1993
- 1993-07-13 DK DK93111194T patent/DK0579169T3/da active
- 1993-07-13 EP EP93111194A patent/EP0579169B1/en not_active Expired - Lifetime
- 1993-07-13 PH PH46513A patent/PH31474A/en unknown
- 1993-07-13 TW TW082105576A patent/TW300895B/zh active
- 1993-07-13 AT AT93111194T patent/ATE170516T1/de not_active IP Right Cessation
- 1993-07-13 DE DE69320730T patent/DE69320730T2/de not_active Expired - Fee Related
- 1993-07-13 CA CA002100376A patent/CA2100376A1/en not_active Abandoned
- 1993-07-13 ES ES93111194T patent/ES2121036T3/es not_active Expired - Lifetime
- 1993-07-14 JP JP5196797A patent/JP2866277B2/ja not_active Expired - Fee Related
- 1993-07-14 MX MX9304259A patent/MX9304259A/es not_active IP Right Cessation
- 1993-07-14 NO NO932551A patent/NO303827B1/no unknown
- 1993-07-14 RU RU93046415/04A patent/RU2069661C1/ru not_active IP Right Cessation
- 1993-07-14 FI FI933206A patent/FI933206A/fi unknown
- 1993-07-14 AU AU41958/93A patent/AU659561B2/en not_active Ceased
- 1993-07-14 CN CN93116490A patent/CN1045597C/zh not_active Expired - Fee Related
- 1993-07-14 HU HU9302017A patent/HU221196B1/hu not_active IP Right Cessation
- 1993-07-14 KR KR1019930013242A patent/KR100293334B1/ko not_active IP Right Cessation
- 1993-07-14 ZA ZA935074A patent/ZA935074B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO303827B1 (no) | 1998-09-07 |
AU659561B2 (en) | 1995-05-18 |
NO932551D0 (no) | 1993-07-14 |
MX9304259A (es) | 1994-03-31 |
FI933206A (fi) | 1994-01-15 |
KR100293334B1 (ko) | 2001-09-17 |
RU2069661C1 (ru) | 1996-11-27 |
KR940005596A (ko) | 1994-03-21 |
ZA935074B (en) | 1994-03-30 |
AU4195893A (en) | 1994-01-20 |
DE69320730T2 (de) | 1999-02-11 |
NO932551L (no) | 1994-01-17 |
TW300895B (es) | 1997-03-21 |
DK0579169T3 (da) | 1999-05-31 |
CN1092412A (zh) | 1994-09-21 |
CN1045597C (zh) | 1999-10-13 |
HUT69392A (en) | 1995-09-28 |
HU9302017D0 (en) | 1993-10-28 |
JP2866277B2 (ja) | 1999-03-08 |
EP0579169B1 (en) | 1998-09-02 |
ATE170516T1 (de) | 1998-09-15 |
DE69320730D1 (de) | 1998-10-08 |
HU221196B1 (en) | 2002-08-28 |
PH31474A (en) | 1998-11-03 |
FI933206A0 (fi) | 1993-07-14 |
EP0579169A1 (en) | 1994-01-19 |
JPH0680645A (ja) | 1994-03-22 |
CA2100376A1 (en) | 1994-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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