DE69514371T2 - Einspritzbares polyethylenoxidgel-implantat und ein verfahren zu seiner herstellung - Google Patents
Einspritzbares polyethylenoxidgel-implantat und ein verfahren zu seiner herstellungInfo
- Publication number
- DE69514371T2 DE69514371T2 DE69514371T DE69514371T DE69514371T2 DE 69514371 T2 DE69514371 T2 DE 69514371T2 DE 69514371 T DE69514371 T DE 69514371T DE 69514371 T DE69514371 T DE 69514371T DE 69514371 T2 DE69514371 T2 DE 69514371T2
- Authority
- DE
- Germany
- Prior art keywords
- polyethylene oxide
- producing
- same
- implant
- oxide gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
- A61F9/0133—Knives or scalpels specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/28—Treatment by wave energy or particle radiation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B2017/320044—Blunt dissectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/12—Mammary prostheses and implants
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
- C08J2371/02—Polyalkylene oxides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/902—Method of implanting
- Y10S623/905—Eye
- Y10S623/906—Corneal
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
- Compounds Of Unknown Constitution (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/299,583 US5634943A (en) | 1990-07-12 | 1994-09-01 | Injectable polyethylene oxide gel implant and method for production |
PCT/US1995/010733 WO1996006883A1 (en) | 1994-09-01 | 1995-08-30 | Injectable polyethylene oxide gel implant and method for production |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69514371D1 DE69514371D1 (de) | 2000-02-10 |
DE69514371T2 true DE69514371T2 (de) | 2000-08-10 |
Family
ID=23155423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69514371T Expired - Fee Related DE69514371T2 (de) | 1994-09-01 | 1995-08-30 | Einspritzbares polyethylenoxidgel-implantat und ein verfahren zu seiner herstellung |
Country Status (15)
Country | Link |
---|---|
US (3) | US5634943A (de) |
EP (1) | EP0778858B1 (de) |
JP (1) | JP3681393B2 (de) |
KR (1) | KR100369961B1 (de) |
AT (1) | ATE188499T1 (de) |
AU (1) | AU690327B2 (de) |
BR (1) | BR9508696A (de) |
CA (1) | CA2198906A1 (de) |
CO (1) | CO4440603A1 (de) |
DE (1) | DE69514371T2 (de) |
ES (1) | ES2145293T3 (de) |
MX (1) | MX9701582A (de) |
TW (1) | TW421600B (de) |
WO (1) | WO1996006883A1 (de) |
ZA (1) | ZA957331B (de) |
Families Citing this family (80)
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US6706690B2 (en) | 1999-06-10 | 2004-03-16 | Baxter Healthcare Corporation | Hemoactive compositions and methods for their manufacture and use |
US7320962B2 (en) | 1996-08-27 | 2008-01-22 | Baxter International Inc. | Hemoactive compositions and methods for their manufacture and use |
US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
US8003705B2 (en) | 1996-09-23 | 2011-08-23 | Incept Llc | Biocompatible hydrogels made with small molecule precursors |
US6152943A (en) * | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
US6605294B2 (en) * | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
FR2786400B1 (fr) * | 1998-11-30 | 2002-05-10 | Imedex Biomateriaux | Procede de preparation d'un materiau collagenique a vitesse de biodegradation in vivo controlee et materiaux obtenus |
AU2707500A (en) | 1998-12-04 | 2000-06-26 | Incept Llc | Biocompatible crosslinked polymers |
US6361560B1 (en) * | 1998-12-23 | 2002-03-26 | Anamed, Inc. | Corneal implant and method of manufacture |
US7635388B1 (en) * | 2000-05-04 | 2009-12-22 | Tyler Thomas D | Device and method for incremental correction of sight disorders and occular diseases |
EP1326506B1 (de) | 2000-09-12 | 2016-04-27 | Revision Optics, Inc. | System zur verpackung und handhabung eines implantats |
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US6296607B1 (en) * | 2000-10-20 | 2001-10-02 | Praxis, Llc. | In situ bulking device |
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BR112017027695A2 (pt) | 2015-07-03 | 2018-09-04 | Ferrosan Medical Devices As | seringa para retenção e mistura de primeira e segunda substâncias |
CN105169469B (zh) * | 2015-08-29 | 2018-05-25 | 北京诺康达医药科技有限公司 | 一种组织密封剂及其制备方法和应用 |
ES2968412T3 (es) | 2018-05-09 | 2024-05-09 | Ferrosan Medical Devices As | Método para preparar una composición hemostática |
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CN112679726B (zh) * | 2020-12-23 | 2023-03-17 | 鸡西市唯大新材料科技有限公司 | 用聚氧化乙烯制备具有亲油及亲水性透明有机凝胶的方法 |
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GB117032A (en) * | 1917-12-31 | 1918-07-04 | Albert Edgar Alexander | Cleaning Shop for Cleansing Work by Means of a Sand Jet. |
US3264202A (en) * | 1961-06-13 | 1966-08-02 | Union Carbide Corp | Ionizing radiation of water solution of polyalkylene oxide and product thereof |
FR1441586A (fr) * | 1965-04-21 | 1966-06-10 | Centre Nat Rech Scient | Gel de polyoxyéthylèneglycol et procédé de préparation |
US3419006A (en) * | 1966-08-08 | 1968-12-31 | Union Carbide Corp | Novel dressing and use thereof |
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DE3343674A1 (de) * | 1983-12-02 | 1985-09-05 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von (alpha) -substituierten acrylsaeureamiden |
US4790919A (en) * | 1984-06-28 | 1988-12-13 | E. I. Du Pont De Nemours And Company | Process for preparation of electrophoresis gel material |
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-
1994
- 1994-09-01 US US08/299,583 patent/US5634943A/en not_active Expired - Lifetime
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1995
- 1995-06-05 US US08/463,591 patent/US5681869A/en not_active Expired - Fee Related
- 1995-06-05 US US08/463,595 patent/US5645583A/en not_active Expired - Lifetime
- 1995-08-30 WO PCT/US1995/010733 patent/WO1996006883A1/en active IP Right Grant
- 1995-08-30 JP JP50884396A patent/JP3681393B2/ja not_active Expired - Fee Related
- 1995-08-30 DE DE69514371T patent/DE69514371T2/de not_active Expired - Fee Related
- 1995-08-30 MX MX9701582A patent/MX9701582A/es unknown
- 1995-08-30 BR BR9508696A patent/BR9508696A/pt not_active IP Right Cessation
- 1995-08-30 TW TW084109067A patent/TW421600B/zh active
- 1995-08-30 ES ES95930930T patent/ES2145293T3/es not_active Expired - Lifetime
- 1995-08-30 KR KR1019970701366A patent/KR100369961B1/ko not_active IP Right Cessation
- 1995-08-30 EP EP95930930A patent/EP0778858B1/de not_active Expired - Lifetime
- 1995-08-30 AT AT95930930T patent/ATE188499T1/de active
- 1995-08-30 AU AU34136/95A patent/AU690327B2/en not_active Ceased
- 1995-08-30 CA CA002198906A patent/CA2198906A1/en not_active Abandoned
- 1995-08-31 ZA ZA957331A patent/ZA957331B/xx unknown
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TW421600B (en) | 2001-02-11 |
KR970705600A (ko) | 1997-10-09 |
CO4440603A1 (es) | 1997-05-07 |
US5634943A (en) | 1997-06-03 |
AU3413695A (en) | 1996-03-22 |
ZA957331B (en) | 1996-04-15 |
KR100369961B1 (ko) | 2003-03-15 |
WO1996006883A1 (en) | 1996-03-07 |
AU690327B2 (en) | 1998-04-23 |
CA2198906A1 (en) | 1996-03-07 |
EP0778858A1 (de) | 1997-06-18 |
ES2145293T3 (es) | 2000-07-01 |
US5681869A (en) | 1997-10-28 |
DE69514371D1 (de) | 2000-02-10 |
US5645583A (en) | 1997-07-08 |
ATE188499T1 (de) | 2000-01-15 |
JP3681393B2 (ja) | 2005-08-10 |
BR9508696A (pt) | 1997-09-09 |
EP0778858B1 (de) | 2000-01-05 |
JPH10505115A (ja) | 1998-05-19 |
MX9701582A (es) | 1998-03-31 |
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