DE69513293T2 - D-mannose- oder xylito-ester und ihre verwenung als arzneimittel - Google Patents

D-mannose- oder xylito-ester und ihre verwenung als arzneimittel

Info

Publication number
DE69513293T2
DE69513293T2 DE69513293T DE69513293T DE69513293T2 DE 69513293 T2 DE69513293 T2 DE 69513293T2 DE 69513293 T DE69513293 T DE 69513293T DE 69513293 T DE69513293 T DE 69513293T DE 69513293 T2 DE69513293 T2 DE 69513293T2
Authority
DE
Germany
Prior art keywords
pct
ester
carbon atom
grouping
mannose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69513293T
Other languages
English (en)
Other versions
DE69513293D1 (de
Inventor
Pierre-Jean Baldwin
Olivier Douillet
Philippe Pouillart
Gino Ronco
Pierre Villa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASSOCIAZIONE DI VOLONTARIATO P
Original Assignee
ASSOCIAZIONE DI VOLONTARIATO P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASSOCIAZIONE DI VOLONTARIATO P filed Critical ASSOCIAZIONE DI VOLONTARIATO P
Application granted granted Critical
Publication of DE69513293D1 publication Critical patent/DE69513293D1/de
Publication of DE69513293T2 publication Critical patent/DE69513293T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/614—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety of phenylacetic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/003—Esters of saturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69513293T 1994-07-28 1995-06-07 D-mannose- oder xylito-ester und ihre verwenung als arzneimittel Expired - Fee Related DE69513293T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409348A FR2723096B1 (fr) 1994-07-28 1994-07-28 Esters associant les acides phenylacetique,3-phenyl-propionique, 4-phenyl-butyrique et n-butyrique au d-mannose, au xylitol et a leurs derives. applications comme medicaments
PCT/FR1995/000743 WO1996003411A1 (fr) 1994-07-28 1995-06-07 Esters du d-mannose ou du xylitol et leur utilisation comme medicaments

Publications (2)

Publication Number Publication Date
DE69513293D1 DE69513293D1 (de) 1999-12-16
DE69513293T2 true DE69513293T2 (de) 2000-03-23

Family

ID=9465834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513293T Expired - Fee Related DE69513293T2 (de) 1994-07-28 1995-06-07 D-mannose- oder xylito-ester und ihre verwenung als arzneimittel

Country Status (13)

Country Link
US (1) US5830872A (de)
EP (1) EP0773949B1 (de)
JP (1) JPH10505334A (de)
AT (1) ATE186543T1 (de)
AU (1) AU698677B2 (de)
CA (1) CA2196091A1 (de)
DE (1) DE69513293T2 (de)
DK (1) DK0773949T3 (de)
ES (1) ES2141359T3 (de)
FR (1) FR2723096B1 (de)
GR (1) GR3032545T3 (de)
NZ (1) NZ288263A (de)
WO (1) WO1996003411A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
WO2003062314A1 (en) * 2002-01-16 2003-07-31 Eastman Chemical Company Novel carbohydrate esters and polyol esters as plasticizers for polymers, compositions and articles including such plasticizers and methods of using the same
KR101286782B1 (ko) * 2005-09-20 2013-07-17 디에스엠 아이피 어셋츠 비.브이. 신규 카복실산 유도체
DE102005046237A1 (de) * 2005-09-28 2007-04-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen
FR2892635B1 (fr) * 2005-10-28 2012-11-09 Engelhard Lyon Substance pour restaurer une co-expression et une interaction normales entre les proteines lox et nrage

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053677A (en) * 1959-11-12 1962-09-11 Eastman Kodak Co Petroleum wax for paper coatings
IL37955A0 (en) * 1970-11-13 1971-12-29 Ciba Geigy Ag O-esters of monosaccharides,their manufacture and pharmaceutical compositions containing them
DE3229956A1 (de) * 1982-08-12 1984-02-16 Erichsen, Friedrich Karl, Dr., 2351 Schillsdorf Arzneimittel mit cytostatischer wirkung
DE3239035A1 (de) * 1982-10-19 1984-04-19 Schering AG, 1000 Berlin und 4709 Bergkamen 2-phenoxypropionsaeurederivate von pentiten, verfahren zur herstellung dieser verbindungen sowie diese enthaltende mittel mit herbizider wirkung
EP0316320B1 (de) * 1986-07-11 1993-11-03 Commonwealth Scientific And Industrial Research Organisation Verminderung von fortpflanzungsausfällen
FR2633929B2 (fr) * 1987-09-25 1995-05-24 Picardie Universite Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees

Also Published As

Publication number Publication date
AU698677B2 (en) 1998-11-05
GR3032545T3 (en) 2000-05-31
EP0773949A1 (de) 1997-05-21
NZ288263A (en) 1998-08-26
DE69513293D1 (de) 1999-12-16
DK0773949T3 (da) 2000-04-17
FR2723096A1 (fr) 1996-02-02
FR2723096B1 (fr) 1996-10-18
WO1996003411A1 (fr) 1996-02-08
EP0773949B1 (de) 1999-11-10
ATE186543T1 (de) 1999-11-15
JPH10505334A (ja) 1998-05-26
ES2141359T3 (es) 2000-03-16
CA2196091A1 (en) 1996-02-08
AU2742295A (en) 1996-02-22
US5830872A (en) 1998-11-03

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Legal Events

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8339 Ceased/non-payment of the annual fee