FR2633929B2 - Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees - Google Patents

Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees

Info

Publication number
FR2633929B2
FR2633929B2 FR8809092A FR8809092A FR2633929B2 FR 2633929 B2 FR2633929 B2 FR 2633929B2 FR 8809092 A FR8809092 A FR 8809092A FR 8809092 A FR8809092 A FR 8809092A FR 2633929 B2 FR2633929 B2 FR 2633929B2
Authority
FR
France
Prior art keywords
toxic
acid derivatives
butyric acid
therapeutic actions
delayed therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8809092A
Other languages
English (en)
Other versions
FR2633929A2 (fr
Inventor
Pieri Francois
Ronco Gino
Segard Emile
Villa Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Picardie Jules Verne
Original Assignee
Universite de Picardie Jules Verne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8713294A external-priority patent/FR2621039B1/fr
Application filed by Universite de Picardie Jules Verne filed Critical Universite de Picardie Jules Verne
Priority to FR8809092A priority Critical patent/FR2633929B2/fr
Priority to DE1988908255 priority patent/DE352301T1/de
Priority to PCT/FR1988/000470 priority patent/WO1989002895A1/fr
Priority to EP88908255A priority patent/EP0352301A1/fr
Publication of FR2633929A2 publication Critical patent/FR2633929A2/fr
Priority to US07/501,080 priority patent/US5185436A/en
Application granted granted Critical
Publication of FR2633929B2 publication Critical patent/FR2633929B2/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8809092A 1987-09-25 1988-07-05 Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees Expired - Lifetime FR2633929B2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR8809092A FR2633929B2 (fr) 1987-09-25 1988-07-05 Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees
DE1988908255 DE352301T1 (de) 1987-09-25 1988-09-26 Buttersaeure-ester und ihre verwendung als arzneimittel.
PCT/FR1988/000470 WO1989002895A1 (fr) 1987-09-25 1988-09-26 Esters de l'acide n-butyrique et leur utilisation comme medicaments
EP88908255A EP0352301A1 (fr) 1987-09-25 1988-09-26 Esters de l'acide n-butyrique et leur utilisation comme medicaments
US07/501,080 US5185436A (en) 1987-09-25 1990-03-29 Esters of normal butyric acid and their use as pharmaceuticals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8713294A FR2621039B1 (fr) 1987-09-25 1987-09-25 Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees
FR8809092A FR2633929B2 (fr) 1987-09-25 1988-07-05 Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees

Publications (2)

Publication Number Publication Date
FR2633929A2 FR2633929A2 (fr) 1990-01-12
FR2633929B2 true FR2633929B2 (fr) 1995-05-24

Family

ID=26226229

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8809092A Expired - Lifetime FR2633929B2 (fr) 1987-09-25 1988-07-05 Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees

Country Status (4)

Country Link
US (1) US5185436A (fr)
EP (1) EP0352301A1 (fr)
FR (1) FR2633929B2 (fr)
WO (1) WO1989002895A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910624B1 (en) 1995-03-03 2011-03-22 The Trustees Of Boston University Compositions for the treatment of blood disorders
AU696167B2 (en) * 1993-10-29 1998-09-03 Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
CA2175249A1 (fr) * 1993-11-10 1995-05-18 Harold L. Newmark Esters butyriques utilises comme agents pour induire une differentiation cellulaire
FR2723096B1 (fr) * 1994-07-28 1996-10-18 Univ Picardie Esters associant les acides phenylacetique,3-phenyl-propionique, 4-phenyl-butyrique et n-butyrique au d-mannose, au xylitol et a leurs derives. applications comme medicaments
US6011000A (en) * 1995-03-03 2000-01-04 Perrine; Susan P. Compositions for the treatment of blood disorders
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6124495A (en) * 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6043389A (en) * 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
DE59812518D1 (de) * 1997-08-08 2005-03-03 Aventis Pharma Gmbh Substituierte tetrahydropyranderivate sowie verfahren zu deren herstellung
WO1999040883A2 (fr) * 1998-02-11 1999-08-19 Faller Douglas V Compositions et techniques de traitement de la mucoviscidose
KR20030020482A (ko) * 2001-08-29 2003-03-10 대한민국(서울대학교) 소디움부티레이트를 유효성분으로 하는 항암제
AU2002348474A1 (en) * 2001-10-18 2003-04-28 The Salk Institute For Biological Studies Methods of using deacetylase inhibitors to promote cell differentiation and regeneration
DE102005046237A1 (de) * 2005-09-28 2007-04-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen
WO2010105112A1 (fr) * 2009-03-11 2010-09-16 Hemaquest Pharmaceuticals, Inc. Détection d'acides gras à chaîne courte dans des échantillons biologiques
US20110086869A1 (en) 2009-09-24 2011-04-14 The Trustees Of Boston University Methods for treating viral disorders
WO2011072086A1 (fr) 2009-12-08 2011-06-16 Hemaquest Pharmaceuticals, Inc. Procédés et régimes à faible dose pour traiter des troubles des globules rouges
WO2011113013A2 (fr) 2010-03-11 2011-09-15 Hemaquest Pharmaceuticals, Inc. Procédés et compositions pour le traitement d'états viraux ou induits par des virus
KR102054401B1 (ko) * 2018-03-26 2019-12-10 주식회사 엔지켐생명과학 1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제
JP2022536256A (ja) 2019-05-31 2022-08-15 ヴィラクタ サブシディアリー，インク． ヒストンデアセチラーゼ阻害剤を用いてウイルス関連癌を治療する方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053677A (en) * 1959-11-12 1962-09-11 Eastman Kodak Co Petroleum wax for paper coatings
DE2903579A1 (de) * 1978-02-03 1979-08-09 Sigma Tau Ind Farmaceuti Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel
JPS5569596A (en) * 1978-11-20 1980-05-26 Asahi Chem Ind Co Ltd Preparation of lactone
US4654370A (en) * 1979-03-12 1987-03-31 Abbott Laboratories Glyceryl valproates
JPS55154992A (en) * 1979-05-22 1980-12-02 Rikagaku Kenkyusho Novel furanose derivative and its preparation
FR2467598B1 (fr) * 1979-10-18 1985-11-15 Bristol Myers Co Composition dermatologique contenant un ou plusieurs triglycerides et son application au traitement de la peau vivante
DE3229956A1 (de) * 1982-08-12 1984-02-16 Erichsen, Friedrich Karl, Dr., 2351 Schillsdorf Arzneimittel mit cytostatischer wirkung
US4497649A (en) * 1983-08-18 1985-02-05 Chevron Research Company 5-O-Acyl-5-C-alkyl-3-O-arylmethyl or substituted arylmethyl-1,2-O-alkylidene-αD-gluco-pentofuranose and β-L-ido-pentofuranose herbicides
DK157308C (da) * 1985-02-27 1990-05-07 Novo Nordisk As Fremgangsmaade til fremstilling af acetal- eller ketalestere af polyoler eller monoestere af mono- eller disaccharider eller monoglycerider

Also Published As

Publication number Publication date
US5185436A (en) 1993-02-09
WO1989002895A1 (fr) 1989-04-06
FR2633929A2 (fr) 1990-01-12
EP0352301A1 (fr) 1990-01-31

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