JPS5791913A - Pharmaceutical preparation of drug - Google Patents

Pharmaceutical preparation of drug

Info

Publication number
JPS5791913A
JPS5791913A JP16893680A JP16893680A JPS5791913A JP S5791913 A JPS5791913 A JP S5791913A JP 16893680 A JP16893680 A JP 16893680A JP 16893680 A JP16893680 A JP 16893680A JP S5791913 A JPS5791913 A JP S5791913A
Authority
JP
Japan
Prior art keywords
drug
adhesive layer
skin
esterified
pharmaceutical preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16893680A
Other languages
Japanese (ja)
Other versions
JPS596287B2 (en
Inventor
Yusuke Ito
Saburo Otsuka
Tetsuo Horiuchi
Toshiyuki Yoshikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Denko Corp
Original Assignee
Nitto Electric Industrial Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Electric Industrial Co Ltd filed Critical Nitto Electric Industrial Co Ltd
Priority to JP16893680A priority Critical patent/JPS596287B2/en
Publication of JPS5791913A publication Critical patent/JPS5791913A/en
Publication of JPS596287B2 publication Critical patent/JPS596287B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: An endermic absorption type pharmaceutical preparation of a drug having improved skin stimulation, comprising a flexible member on one side of it, obtained by esterifying a specific non-steroid type antiphlogistic drug, and distributing the drug esterified uniformly into an acrylic type pressure-sensitive adhesive layer nonstimulating the skin.
CONSTITUTION: A non-steroid type antiphlogistic drug having a carboxyl group in the molecule being solid at normal temperature, e.g., indomethacin, etc. is esterified with 1W8C alcohol, and the drug is distributed uniformly into an acrylic type pressure-sensitive adhesive layer, having low stimulation to the skin, having improved compatibility with the esterified derivative and not crystallizing. A penetration auxiliary may be added to the adhesive layer. A flexible member is equipped on the opposite face of the adhesive layer, following the applied face, to give an endermic absorption type pharmaceutical preparation of a drug resolving various kinds of problems caused by the drug, having especially low skin stimulation, improved shelf stability, and high acute toxicity value.
COPYRIGHT: (C)1982,JPO&Japio
JP16893680A 1980-11-28 1980-11-28 pharmaceutical formulations Expired JPS596287B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16893680A JPS596287B2 (en) 1980-11-28 1980-11-28 pharmaceutical formulations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16893680A JPS596287B2 (en) 1980-11-28 1980-11-28 pharmaceutical formulations

Publications (2)

Publication Number Publication Date
JPS5791913A true JPS5791913A (en) 1982-06-08
JPS596287B2 JPS596287B2 (en) 1984-02-10

Family

ID=15877280

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16893680A Expired JPS596287B2 (en) 1980-11-28 1980-11-28 pharmaceutical formulations

Country Status (1)

Country Link
JP (1) JPS596287B2 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505891A (en) * 1980-10-20 1985-03-19 Nichiban Co., Ltd. Medicinal adhesive sheets for heart diseases and a process for the preparation thereof
JPS61165325A (en) * 1985-11-08 1986-07-26 Nippon Redarii Kk Anti-inflammatory and analgesic gel ointment
JPS62126124A (en) * 1985-10-28 1987-06-08 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド Composition for percutaneous administration drug
FR2719770A1 (en) * 1994-05-11 1995-11-17 Lhd Lab Hygiene Dietetique Matrix system for transdermal delivery of ibuprofen and method of preparation
US5614178A (en) * 1992-07-28 1997-03-25 The Procter & Gamble Company Compositions for topical delivery of drugs comprising a mixture of high and low HLB surfactants and alkoxylated ether
US5707635A (en) * 1991-10-16 1998-01-13 Richardson-Vicks Inc. Gel type cosmetic compositions
US5776485A (en) * 1991-10-16 1998-07-07 Richardson-Vicks Inc. Enhanced skin penetration system for improved topical delivery of drugs
US5989536A (en) * 1993-07-03 1999-11-23 The Procter & Gamble Company Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin
US6277892B1 (en) 1991-10-16 2001-08-21 Schering-Plough Healthcare Products, Inc. Enhanced skin penetration system for improved topical delivery of drugs
JP2008531693A (en) * 2005-03-03 2008-08-14 アイ エス ダブリュ グループ インコーポレイテッド Gel composition for topical use

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505891A (en) * 1980-10-20 1985-03-19 Nichiban Co., Ltd. Medicinal adhesive sheets for heart diseases and a process for the preparation thereof
JPS62126124A (en) * 1985-10-28 1987-06-08 エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド Composition for percutaneous administration drug
JPS61165325A (en) * 1985-11-08 1986-07-26 Nippon Redarii Kk Anti-inflammatory and analgesic gel ointment
JPH0362694B2 (en) * 1985-11-08 1991-09-26 Lederle Japan Ltd
US5874095A (en) * 1991-10-16 1999-02-23 Richardson-Vicks Inc. Enhanced skin penetration system for improved topical delivery of drugs
US5707635A (en) * 1991-10-16 1998-01-13 Richardson-Vicks Inc. Gel type cosmetic compositions
US5776485A (en) * 1991-10-16 1998-07-07 Richardson-Vicks Inc. Enhanced skin penetration system for improved topical delivery of drugs
US6277892B1 (en) 1991-10-16 2001-08-21 Schering-Plough Healthcare Products, Inc. Enhanced skin penetration system for improved topical delivery of drugs
US5614178A (en) * 1992-07-28 1997-03-25 The Procter & Gamble Company Compositions for topical delivery of drugs comprising a mixture of high and low HLB surfactants and alkoxylated ether
US5989536A (en) * 1993-07-03 1999-11-23 The Procter & Gamble Company Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin
WO1995031193A1 (en) * 1994-05-11 1995-11-23 Laboratoires D'hygiene Et De Dietetique Matrix system for the transdermal delivery of ibuprofen, and method for preparing same
FR2719770A1 (en) * 1994-05-11 1995-11-17 Lhd Lab Hygiene Dietetique Matrix system for transdermal delivery of ibuprofen and method of preparation
JP2008531693A (en) * 2005-03-03 2008-08-14 アイ エス ダブリュ グループ インコーポレイテッド Gel composition for topical use

Also Published As

Publication number Publication date
JPS596287B2 (en) 1984-02-10

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