JPS5791913A - Pharmaceutical preparation of drug - Google Patents
Pharmaceutical preparation of drugInfo
- Publication number
- JPS5791913A JPS5791913A JP16893680A JP16893680A JPS5791913A JP S5791913 A JPS5791913 A JP S5791913A JP 16893680 A JP16893680 A JP 16893680A JP 16893680 A JP16893680 A JP 16893680A JP S5791913 A JPS5791913 A JP S5791913A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- adhesive layer
- skin
- esterified
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: An endermic absorption type pharmaceutical preparation of a drug having improved skin stimulation, comprising a flexible member on one side of it, obtained by esterifying a specific non-steroid type antiphlogistic drug, and distributing the drug esterified uniformly into an acrylic type pressure-sensitive adhesive layer nonstimulating the skin.
CONSTITUTION: A non-steroid type antiphlogistic drug having a carboxyl group in the molecule being solid at normal temperature, e.g., indomethacin, etc. is esterified with 1W8C alcohol, and the drug is distributed uniformly into an acrylic type pressure-sensitive adhesive layer, having low stimulation to the skin, having improved compatibility with the esterified derivative and not crystallizing. A penetration auxiliary may be added to the adhesive layer. A flexible member is equipped on the opposite face of the adhesive layer, following the applied face, to give an endermic absorption type pharmaceutical preparation of a drug resolving various kinds of problems caused by the drug, having especially low skin stimulation, improved shelf stability, and high acute toxicity value.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16893680A JPS596287B2 (en) | 1980-11-28 | 1980-11-28 | pharmaceutical formulations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16893680A JPS596287B2 (en) | 1980-11-28 | 1980-11-28 | pharmaceutical formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5791913A true JPS5791913A (en) | 1982-06-08 |
JPS596287B2 JPS596287B2 (en) | 1984-02-10 |
Family
ID=15877280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16893680A Expired JPS596287B2 (en) | 1980-11-28 | 1980-11-28 | pharmaceutical formulations |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS596287B2 (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4505891A (en) * | 1980-10-20 | 1985-03-19 | Nichiban Co., Ltd. | Medicinal adhesive sheets for heart diseases and a process for the preparation thereof |
JPS61165325A (en) * | 1985-11-08 | 1986-07-26 | Nippon Redarii Kk | Anti-inflammatory and analgesic gel ointment |
JPS62126124A (en) * | 1985-10-28 | 1987-06-08 | エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド | Composition for percutaneous administration drug |
FR2719770A1 (en) * | 1994-05-11 | 1995-11-17 | Lhd Lab Hygiene Dietetique | Matrix system for transdermal delivery of ibuprofen and method of preparation |
US5614178A (en) * | 1992-07-28 | 1997-03-25 | The Procter & Gamble Company | Compositions for topical delivery of drugs comprising a mixture of high and low HLB surfactants and alkoxylated ether |
US5707635A (en) * | 1991-10-16 | 1998-01-13 | Richardson-Vicks Inc. | Gel type cosmetic compositions |
US5776485A (en) * | 1991-10-16 | 1998-07-07 | Richardson-Vicks Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
US5989536A (en) * | 1993-07-03 | 1999-11-23 | The Procter & Gamble Company | Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin |
US6277892B1 (en) | 1991-10-16 | 2001-08-21 | Schering-Plough Healthcare Products, Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
JP2008531693A (en) * | 2005-03-03 | 2008-08-14 | アイ エス ダブリュ グループ インコーポレイテッド | Gel composition for topical use |
-
1980
- 1980-11-28 JP JP16893680A patent/JPS596287B2/en not_active Expired
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4505891A (en) * | 1980-10-20 | 1985-03-19 | Nichiban Co., Ltd. | Medicinal adhesive sheets for heart diseases and a process for the preparation thereof |
JPS62126124A (en) * | 1985-10-28 | 1987-06-08 | エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド | Composition for percutaneous administration drug |
JPS61165325A (en) * | 1985-11-08 | 1986-07-26 | Nippon Redarii Kk | Anti-inflammatory and analgesic gel ointment |
JPH0362694B2 (en) * | 1985-11-08 | 1991-09-26 | Lederle Japan Ltd | |
US5874095A (en) * | 1991-10-16 | 1999-02-23 | Richardson-Vicks Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
US5707635A (en) * | 1991-10-16 | 1998-01-13 | Richardson-Vicks Inc. | Gel type cosmetic compositions |
US5776485A (en) * | 1991-10-16 | 1998-07-07 | Richardson-Vicks Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
US6277892B1 (en) | 1991-10-16 | 2001-08-21 | Schering-Plough Healthcare Products, Inc. | Enhanced skin penetration system for improved topical delivery of drugs |
US5614178A (en) * | 1992-07-28 | 1997-03-25 | The Procter & Gamble Company | Compositions for topical delivery of drugs comprising a mixture of high and low HLB surfactants and alkoxylated ether |
US5989536A (en) * | 1993-07-03 | 1999-11-23 | The Procter & Gamble Company | Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin |
WO1995031193A1 (en) * | 1994-05-11 | 1995-11-23 | Laboratoires D'hygiene Et De Dietetique | Matrix system for the transdermal delivery of ibuprofen, and method for preparing same |
FR2719770A1 (en) * | 1994-05-11 | 1995-11-17 | Lhd Lab Hygiene Dietetique | Matrix system for transdermal delivery of ibuprofen and method of preparation |
JP2008531693A (en) * | 2005-03-03 | 2008-08-14 | アイ エス ダブリュ グループ インコーポレイテッド | Gel composition for topical use |
Also Published As
Publication number | Publication date |
---|---|
JPS596287B2 (en) | 1984-02-10 |
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