DE69427966D1 - Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten - Google Patents

Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten

Info

Publication number
DE69427966D1
DE69427966D1 DE69427966T DE69427966T DE69427966D1 DE 69427966 D1 DE69427966 D1 DE 69427966D1 DE 69427966 T DE69427966 T DE 69427966T DE 69427966 T DE69427966 T DE 69427966T DE 69427966 D1 DE69427966 D1 DE 69427966D1
Authority
DE
Germany
Prior art keywords
gangliosides
lyso
derivatives
acyl
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427966T
Other languages
English (en)
Other versions
DE69427966T2 (de
Inventor
Aurelio Romeo
Guenter Kirschner
Carlo Chizzolini
Hari Manev
Laura Facci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia Farmaceutici SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of DE69427966D1 publication Critical patent/DE69427966D1/de
Application granted granted Critical
Publication of DE69427966T2 publication Critical patent/DE69427966T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69427966T 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten Expired - Fee Related DE69427966T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi
PCT/US1994/001965 WO1994020515A1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives

Publications (2)

Publication Number Publication Date
DE69427966D1 true DE69427966D1 (de) 2001-09-20
DE69427966T2 DE69427966T2 (de) 2002-04-04

Family

ID=11390210

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427966T Expired - Fee Related DE69427966T2 (de) 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten

Country Status (10)

Country Link
EP (1) EP0688330B1 (de)
JP (1) JPH08507307A (de)
KR (1) KR960701073A (de)
AT (1) ATE204287T1 (de)
AU (1) AU694105B2 (de)
CA (1) CA2157359A1 (de)
DE (1) DE69427966T2 (de)
ES (1) ES2159554T3 (de)
IT (1) IT1267956B1 (de)
WO (1) WO1994020515A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
JP5663576B2 (ja) 2010-07-06 2015-02-04 上西　秀則 神経突起伸長剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
JPH03246297A (ja) * 1990-02-22 1991-11-01 Nippon Koutai Kenkyusho:Kk ガングリオシド誘導体及びこれを含有する抗ｈｉｖ剤
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
ITPD930045A1 (it) 1994-09-04
IT1267956B1 (it) 1997-02-18
EP0688330B1 (de) 2001-08-16
AU694105B2 (en) 1998-07-16
AU6352194A (en) 1994-09-26
ITPD930045A0 (it) 1993-03-04
WO1994020515A1 (en) 1994-09-15
DE69427966T2 (de) 2002-04-04
CA2157359A1 (en) 1994-09-15
EP0688330A1 (de) 1995-12-27
ES2159554T3 (es) 2001-10-16
JPH08507307A (ja) 1996-08-06
KR960701073A (ko) 1996-02-24
ATE204287T1 (de) 2001-09-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: FIDIA FARMACEUTICI S.P.A., ABANO TERME, PADUA/PADO

8339 Ceased/non-payment of the annual fee