DE69426304T2 - Methoden zur regulation der den magen und darm betreffenden motilitaet - Google Patents

Methoden zur regulation der den magen und darm betreffenden motilitaet

Info

Publication number
DE69426304T2
DE69426304T2 DE69426304T DE69426304T DE69426304T2 DE 69426304 T2 DE69426304 T2 DE 69426304T2 DE 69426304 T DE69426304 T DE 69426304T DE 69426304 T DE69426304 T DE 69426304T DE 69426304 T2 DE69426304 T2 DE 69426304T2
Authority
DE
Germany
Prior art keywords
methods
stomach
regulation
bowel motility
gastric emptying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69426304T
Other languages
English (en)
Other versions
DE69426304D1 (de
Inventor
G Kolterman
A Young
J Rink
Keiting Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylin Pharmaceuticals LLC
Original Assignee
Amylin Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals LLC filed Critical Amylin Pharmaceuticals LLC
Publication of DE69426304D1 publication Critical patent/DE69426304D1/de
Application granted granted Critical
Publication of DE69426304T2 publication Critical patent/DE69426304T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69426304T 1993-09-07 1994-09-07 Methoden zur regulation der den magen und darm betreffenden motilitaet Expired - Lifetime DE69426304T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11838193A 1993-09-07 1993-09-07
PCT/US1994/010225 WO1995007098A1 (en) 1993-09-07 1994-09-07 Methods for regulating gastrointestinal motility

Publications (2)

Publication Number Publication Date
DE69426304D1 DE69426304D1 (de) 2000-12-21
DE69426304T2 true DE69426304T2 (de) 2001-03-15

Family

ID=22378228

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69426304T Expired - Lifetime DE69426304T2 (de) 1993-09-07 1994-09-07 Methoden zur regulation der den magen und darm betreffenden motilitaet

Country Status (23)

Country Link
US (4) US6114304A (de)
EP (1) EP0717635B1 (de)
JP (2) JP3821839B2 (de)
KR (2) KR100391399B1 (de)
CN (1) CN1134110A (de)
AT (1) ATE197549T1 (de)
AU (1) AU7685894A (de)
BG (1) BG100463A (de)
BR (1) BR9407424A (de)
CA (1) CA2171207C (de)
CZ (1) CZ69596A3 (de)
DE (1) DE69426304T2 (de)
DK (1) DK0717635T3 (de)
ES (1) ES2154299T3 (de)
GR (1) GR3035387T3 (de)
HU (1) HUT73490A (de)
NO (1) NO960899L (de)
PT (1) PT717635E (de)
RU (1) RU2177331C2 (de)
SG (1) SG98356A1 (de)
SK (1) SK31496A3 (de)
WO (1) WO1995007098A1 (de)
ZA (1) ZA946881B (de)

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ZA946881B (en) * 1993-09-07 1995-10-30 Amylin Pharmaceuticals Inc Methods for treating gastrointestinal motility
US6143718A (en) 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
CA2262647C (en) * 1996-08-08 2007-12-04 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
ES2247676T3 (es) 1997-01-07 2006-03-01 Amylin Pharmaceuticals, Inc. Uso de las exendinas y de los agonistas de las mismas para la reduccion de la ingesta alimenticia.
US7101853B2 (en) 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
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JP4372345B2 (ja) 1998-02-13 2009-11-25 アミリン・ファーマシューティカルズ,インコーポレイテッド 新規な混合アミリン活性化合物
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ES2343072T3 (es) 1999-01-14 2010-07-22 Amylin Pharmaceuticals, Inc. Exendina para la supresion del glucagon.
US7399489B2 (en) 1999-01-14 2008-07-15 Amylin Pharmaceuticals, Inc. Exendin analog formulations
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US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
EP1261282B1 (de) 2000-03-03 2013-09-25 C. R. Bard, Inc. Endoskopisches gewebeappositionsgerät mit mehreren absaugöffnungen
US7220266B2 (en) 2000-05-19 2007-05-22 C. R. Bard, Inc. Tissue capturing and suturing device and method
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US20040126318A1 (en) * 2002-09-12 2004-07-01 Ehrenpreis Eli D. Methods, formulations and kits for monitoring and diagnosing gastric emptying and gastroparesis, and formulations for determining gastrointestinal motility
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US7655618B2 (en) * 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
WO2005021026A2 (en) * 2003-08-29 2005-03-10 Amylin Pharmaceuticals, Inc. Methods for treating or ameliorating ghrelin-associated diseases and disorders
RU2385878C2 (ru) * 2004-02-11 2010-04-10 Амилин Фармасьютикалз, Инк. Пептид, обладающий свойствами амилина (варианты), и его применение (варианты)
US7399744B2 (en) * 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
US7878978B2 (en) 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
US8172857B2 (en) 2004-08-27 2012-05-08 Davol, Inc. Endoscopic tissue apposition device and method of use
US8394765B2 (en) * 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
EP1814590B2 (de) 2004-11-01 2013-12-11 Amylin Pharmaceuticals, Inc. Behandlung von fettsucht und verbundenen erkrankungen
JP5114381B2 (ja) * 2005-03-31 2013-01-09 アミリン・ファーマシューティカルズ,インコーポレイテッド 精神疾患および障害治療用アミリンおよびアミリンアゴニスト
EP1996224B1 (de) 2006-03-15 2012-11-07 Novo Nordisk A/S Mischungen aus amylin und insulin
WO2007112069A2 (en) * 2006-03-23 2007-10-04 Amylin Pharmaceuticals, Inc. Endothelin and endothelin receptor agonists in the treatment of metabolic diseases
US20090181890A1 (en) * 2006-03-31 2009-07-16 Amylin Pharmaceuticals , Inc. Amylin and Amylin Agonists for Treating Psychiatric Diseases and Disorders
EP2120985B1 (de) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 Peptide zur Verwendung bei der Behandlung Psychotischer- und Angsterkrankungen
BRPI0722276A2 (pt) * 2007-11-14 2014-04-22 Amylin Pharmaceuticals Inc Métodos para tratar obesidade e doenças e distúrbios relacionados à obesidade
EP2762150A1 (de) 2009-03-12 2014-08-06 Nordic Bioscience A/S Behandlung von Diabetes und Stoffwechselsyndrom
WO2010107874A2 (en) * 2009-03-17 2010-09-23 Amylin Pharmaceuticals, Inc. Methods for affecting body composition using amylin agonists
MX343360B (es) 2010-04-27 2016-11-03 Zealand Pharma As Conjugados peptidicos de agonistas del receptor de glp-1 y gastrina y su uso.
CN104144704B (zh) 2011-11-03 2018-03-23 西兰制药公司 Glp‑1受体激动剂肽胃泌素缀合物
AR091866A1 (es) 2012-07-23 2015-03-04 Zealand Pharma As Analogos del glucagon
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
UA122767C2 (uk) 2013-10-17 2021-01-06 Зіленд Фарма А/С Ацильований аналог глюкагону
EA035688B1 (ru) 2013-11-06 2020-07-27 Зилэнд Фарма А/С Соединения, которые представляют собой тройные агонисты глюкагона, glp-1 и gip
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WO2019115411A1 (fr) 2017-12-07 2019-06-20 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3083086A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
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Also Published As

Publication number Publication date
SG98356A1 (en) 2003-09-19
JP3821839B2 (ja) 2006-09-13
EP0717635B1 (de) 2000-11-15
DE69426304D1 (de) 2000-12-21
US20040097415A1 (en) 2004-05-20
JP2004331674A (ja) 2004-11-25
CN1134110A (zh) 1996-10-23
BG100463A (en) 1997-03-31
KR100391399B1 (ko) 2004-02-11
US7407934B2 (en) 2008-08-05
JPH09502443A (ja) 1997-03-11
US5795861A (en) 1998-08-18
EP0717635A1 (de) 1996-06-26
AU7685894A (en) 1995-03-27
ES2154299T3 (es) 2001-04-01
SK31496A3 (en) 1998-06-03
HUT73490A (en) 1996-08-28
PT717635E (pt) 2001-04-30
KR100429966B1 (ko) 2004-05-04
HU9600558D0 (en) 1996-05-28
NO960899L (no) 1996-05-06
ZA946881B (en) 1995-10-30
CA2171207A1 (en) 1995-03-16
DK0717635T3 (da) 2000-12-11
US6608029B1 (en) 2003-08-19
KR20040004418A (ko) 2004-01-13
RU2177331C2 (ru) 2001-12-27
CZ69596A3 (en) 1997-06-11
ATE197549T1 (de) 2000-12-15
BR9407424A (pt) 1996-04-09
WO1995007098A1 (en) 1995-03-16
CA2171207C (en) 2010-03-30
GR3035387T3 (en) 2001-05-31
NO960899D0 (no) 1996-03-06
US6114304A (en) 2000-09-05

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