ES2154299T3 - Metodos para la regulacion de la motilidad gastrointestinal. - Google Patents

Metodos para la regulacion de la motilidad gastrointestinal.

Info

Publication number
ES2154299T3
ES2154299T3 ES94927398T ES94927398T ES2154299T3 ES 2154299 T3 ES2154299 T3 ES 2154299T3 ES 94927398 T ES94927398 T ES 94927398T ES 94927398 T ES94927398 T ES 94927398T ES 2154299 T3 ES2154299 T3 ES 2154299T3
Authority
ES
Spain
Prior art keywords
methods
regulation
gastrointestinal motility
gastric emptying
inappropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94927398T
Other languages
English (en)
Inventor
Orville G Kolterman
Andrew A Young
Timothy J Rink
Kathleen Keiting Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylin Pharmaceuticals LLC
Original Assignee
Amylin Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals LLC filed Critical Amylin Pharmaceuticals LLC
Application granted granted Critical
Publication of ES2154299T3 publication Critical patent/ES2154299T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

SE DESCRIBEN METODOS PARA EL TRATAMIENTO DE CONDICIONES ASOCIADAS CON NIVELES SANGUINEOS POST-PANDRIALES ELEVADOS INAPROPIADOS O NO DESEADOS QUE COMPRENDEN LA ADMINISTRACION DE UNA CANTIDAD EFECTIVA DE UN AGONISTA DE AMILINA SOLO O EN CONJUNCION CON OTROS AGENTES DE VACIADO ANTI-GASTRICO. TAMBIEN SE DESCRIBEN METODOS PARA REDUCIR LA MOVILIDAD GASTRICA Y RETRASAR EL VACIADO GASTRICO PARA PROPOSITOS TERAPEUTICOS Y DE DIAGNOSTICO.
ES94927398T 1993-09-07 1994-09-07 Metodos para la regulacion de la motilidad gastrointestinal. Expired - Lifetime ES2154299T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11838193A 1993-09-07 1993-09-07

Publications (1)

Publication Number Publication Date
ES2154299T3 true ES2154299T3 (es) 2001-04-01

Family

ID=22378228

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94927398T Expired - Lifetime ES2154299T3 (es) 1993-09-07 1994-09-07 Metodos para la regulacion de la motilidad gastrointestinal.

Country Status (23)

Country Link
US (4) US6114304A (es)
EP (1) EP0717635B1 (es)
JP (2) JP3821839B2 (es)
KR (2) KR100429966B1 (es)
CN (1) CN1134110A (es)
AT (1) ATE197549T1 (es)
AU (1) AU7685894A (es)
BG (1) BG100463A (es)
BR (1) BR9407424A (es)
CA (1) CA2171207C (es)
CZ (1) CZ69596A3 (es)
DE (1) DE69426304T2 (es)
DK (1) DK0717635T3 (es)
ES (1) ES2154299T3 (es)
GR (1) GR3035387T3 (es)
HU (1) HUT73490A (es)
NO (1) NO960899L (es)
PT (1) PT717635E (es)
RU (1) RU2177331C2 (es)
SG (1) SG98356A1 (es)
SK (1) SK31496A3 (es)
WO (1) WO1995007098A1 (es)
ZA (1) ZA946881B (es)

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US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
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US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
EP0717635B1 (en) * 1993-09-07 2000-11-15 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US6143718A (en) 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
EP2016950B1 (en) 1996-08-08 2011-01-05 Amylin Pharmaceuticals, Inc. Pharmaceutical composition comprising an exendin-4 peptide
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US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
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US6902744B1 (en) 1999-01-14 2005-06-07 Amylin Pharmaceuticals, Inc. Exendin agonist formulations and methods of administration thereof
ATE347901T1 (de) 1999-01-14 2007-01-15 Amylin Pharmaceuticals Inc Exendine zur glucagon suppression
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US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
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ES2435094T3 (es) 2000-05-19 2013-12-18 C.R. Bard, Inc. Dispositivo y método de captura y sutura de tejido
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US7314859B2 (en) * 2002-12-27 2008-01-01 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
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US20070275877A1 (en) * 2003-08-29 2007-11-29 Amylin Pharmaceuticals, Inc. Methods for Treating or Ameliorating Ghrelin-Associated Diseases and Disorders
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US7399744B2 (en) * 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
US7878978B2 (en) 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
US8172857B2 (en) 2004-08-27 2012-05-08 Davol, Inc. Endoscopic tissue apposition device and method of use
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US8394765B2 (en) * 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
ATE439140T1 (de) 2005-03-31 2009-08-15 Amylin Pharmaceuticals Inc Amylin und amylinagonisten für die behandlung von psychiatrischen erkrankungen und störungen
JP5312054B2 (ja) 2006-03-15 2013-10-09 ノボ・ノルデイスク・エー/エス アミリンとインスリンの混合物
US20100004166A1 (en) * 2006-03-23 2010-01-07 Richard Pittner Endothelin and Endothelin Receptor Agonists in the Treatment of Metabolic Diseases
US20090181890A1 (en) * 2006-03-31 2009-07-16 Amylin Pharmaceuticals , Inc. Amylin and Amylin Agonists for Treating Psychiatric Diseases and Disorders
US8309522B2 (en) 2007-02-05 2012-11-13 Amylin Pharmaceuticals, Llc Neuromedin and FN-38 peptides for treating psychiatric diseases
AU2007360979B2 (en) * 2007-11-14 2014-04-10 Amylin Pharmaceuticals, Llc Methods for treating obesity and obesity related diseases and disorders
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US8748375B2 (en) * 2009-03-17 2014-06-10 Amylin Pharmaceuticals, Llc Methods for affecting body composition using amylin agonists
JP5969461B2 (ja) 2010-04-27 2016-08-17 ジーランド ファーマ アクティーゼルスカブ Glp−1受容体作動薬とガストリンとのペプチド複合体及びその使用
CA2853884A1 (en) 2011-11-03 2013-05-10 Zealand Pharma A/S Glp-1 receptor agonist peptide gastrin conjugates
WO2014016300A1 (en) 2012-07-23 2014-01-30 Zealand Pharma A/S Glucagon analogues
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
BR112016008115B1 (pt) 2013-10-17 2024-03-12 Boehringer Ingelheim International Gmbh Análogos de glucagon acilados
BR112016009995B1 (pt) 2013-11-06 2023-04-18 Zealand Pharma A/S Compostos agonistas triplos glucagon-glp-1-gip
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KR102502040B1 (ko) 2016-12-09 2023-02-24 질랜드 파마 에이/에스 아실화 glp-1/glp-2 이중 효능제
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SG11202000625PA (en) 2017-07-27 2020-02-27 Adocia Compositions in the form of an injectable aqueous solution comprising at least human insulin a21g and a prandial action glucagon suppressor
US11173109B2 (en) 2017-12-07 2021-11-16 Adocia Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid
CA3084699A1 (en) 2017-12-07 2019-06-13 Adocia Compositions in the form of an injectable aqueous solution comprising amylin, an amylin agonist receptor or an amylin analog and a co-polyamino acid
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FR3083086A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3083085B1 (fr) 2018-06-29 2020-10-02 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
US20190275108A1 (en) 2017-12-07 2019-09-12 Adocia Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analogue and a co-polyamino acid
FR3084586B1 (fr) 2018-08-03 2020-11-06 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un compose amphiphile porteur de radicaux hydrophobes

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Also Published As

Publication number Publication date
KR100391399B1 (ko) 2004-02-11
NO960899D0 (no) 1996-03-06
CA2171207C (en) 2010-03-30
WO1995007098A1 (en) 1995-03-16
DE69426304D1 (de) 2000-12-21
JP3821839B2 (ja) 2006-09-13
AU7685894A (en) 1995-03-27
US6114304A (en) 2000-09-05
RU2177331C2 (ru) 2001-12-27
JPH09502443A (ja) 1997-03-11
HU9600558D0 (en) 1996-05-28
DK0717635T3 (da) 2000-12-11
JP2004331674A (ja) 2004-11-25
HUT73490A (en) 1996-08-28
KR100429966B1 (ko) 2004-05-04
US7407934B2 (en) 2008-08-05
DE69426304T2 (de) 2001-03-15
SK31496A3 (en) 1998-06-03
KR20040004418A (ko) 2004-01-13
ATE197549T1 (de) 2000-12-15
EP0717635B1 (en) 2000-11-15
PT717635E (pt) 2001-04-30
CA2171207A1 (en) 1995-03-16
US20040097415A1 (en) 2004-05-20
US6608029B1 (en) 2003-08-19
CN1134110A (zh) 1996-10-23
EP0717635A1 (en) 1996-06-26
US5795861A (en) 1998-08-18
NO960899L (no) 1996-05-06
GR3035387T3 (en) 2001-05-31
SG98356A1 (en) 2003-09-19
BR9407424A (pt) 1996-04-09
ZA946881B (en) 1995-10-30
CZ69596A3 (en) 1997-06-11
BG100463A (en) 1997-03-31

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