DE69416824T2 - Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen - Google Patents

Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen

Info

Publication number
DE69416824T2
DE69416824T2 DE69416824T DE69416824T DE69416824T2 DE 69416824 T2 DE69416824 T2 DE 69416824T2 DE 69416824 T DE69416824 T DE 69416824T DE 69416824 T DE69416824 T DE 69416824T DE 69416824 T2 DE69416824 T2 DE 69416824T2
Authority
DE
Germany
Prior art keywords
pct
hiv
polypeptides
polypeptide
products made
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416824T
Other languages
English (en)
Other versions
DE69416824D1 (de
Inventor
Akiyoshi Matsumoto
Michinori Waki
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Application granted granted Critical
Publication of DE69416824D1 publication Critical patent/DE69416824D1/de
Publication of DE69416824T2 publication Critical patent/DE69416824T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69416824T 1993-10-14 1994-10-12 Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen Expired - Fee Related DE69416824T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28034693 1993-10-14
PCT/JP1994/001706 WO1995010534A1 (en) 1993-10-14 1994-10-12 Polypeptide and anti-hiv agent prepared therefrom

Publications (2)

Publication Number Publication Date
DE69416824D1 DE69416824D1 (de) 1999-04-08
DE69416824T2 true DE69416824T2 (de) 1999-07-08

Family

ID=17623732

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416824T Expired - Fee Related DE69416824T2 (de) 1993-10-14 1994-10-12 Polypeptide und daraus hergestellte, gegen hiv wirksame substanzen

Country Status (17)

Country Link
US (1) US5776899A (de)
EP (1) EP0677061B1 (de)
JP (1) JPH08504837A (de)
KR (1) KR100208873B1 (de)
CN (1) CN1038841C (de)
AT (1) ATE177114T1 (de)
AU (1) AU682405B2 (de)
CA (1) CA2151283A1 (de)
CZ (1) CZ287239B6 (de)
DE (1) DE69416824T2 (de)
FI (1) FI952900A0 (de)
HU (1) HU217442B (de)
NO (1) NO952321L (de)
NZ (1) NZ274560A (de)
RU (1) RU2136696C1 (de)
WO (1) WO1995010534A1 (de)
ZA (1) ZA948005B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
US6653442B1 (en) 1993-07-20 2003-11-25 Intrabiotics Pharmaceuticals, Inc. Protegrins
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US6025326A (en) * 1995-07-07 2000-02-15 Intrabiotics Pharmaceuticals, Inc. Compositions and methods for the prevention and treatment of oral mucositis
US5994306A (en) * 1995-11-22 1999-11-30 Intrabiotics Pharmaceuticals, Inc. Fine-tuned protegrins
US5916872A (en) * 1996-07-24 1999-06-29 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity
RU2179981C2 (ru) * 1996-10-15 2002-02-27 Сейкагаку Корпорейшн Соли переходного металла с полипептидом и способ повышения активности полипептида против вич
AU6518698A (en) * 1997-03-28 1998-10-22 Seikagaku Corporation Novel anti-hiv complexes and medicinal compositions
CA2378480A1 (en) * 1999-08-09 2001-02-15 Tripep Ab Pharmaceutical compositions containing tripeptides
US6337317B1 (en) * 2000-06-27 2002-01-08 The University Of British Columbia Antimicrobial peptides and methods of use thereof
AU2001284419A1 (en) 2000-09-05 2002-03-22 Seikagaku Corporation Novel polypeptides and anti-hiv drugs containing the same
US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
WO2003024995A1 (en) * 2001-09-19 2003-03-27 Tripep Ab Molecules that block viral infectivity and methods of use thereof
KR100932520B1 (ko) * 2002-10-31 2009-12-17 박래옥 항암제 조성물
EP1541585B1 (de) * 2002-08-27 2013-01-30 Biokine Therapeutics Ltd. Cxcr4-antagonist und dessen verwendung
JP4781621B2 (ja) * 2002-08-27 2011-09-28 バイオカイン セラピューティックス リミテッド Cxcr4拮抗薬およびその用途
US20070166401A1 (en) * 2002-10-31 2007-07-19 Lae-Ok Park Anticancer or antiviral composition
US20040132642A1 (en) * 2002-11-12 2004-07-08 Government Of The U.S.A., Represented By The Secretary, Dept. Of Health & Human Services Methods of inhibiting metastasis or growth of a tumor cell
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
EP1603546A1 (de) * 2003-02-21 2005-12-14 Tripep AB Glycinamid-derivat zur hemmung der hiv-replikation
WO2004096839A1 (en) 2003-05-02 2004-11-11 Polyphor Ag Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity
KR20080106467A (ko) 2006-03-10 2008-12-05 펩트셀 리미티드 Hiv 조절 또는 보조 단백질의 펩타이드, 그 조성물 및 이용 방법
CN100366633C (zh) * 2006-04-18 2008-02-06 河北师范大学 棕点湍蛙抗病毒多肽及其在制药中的应用
WO2008075371A2 (en) 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation
US9789194B2 (en) 2007-11-27 2017-10-17 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
US9271933B2 (en) * 2007-11-27 2016-03-01 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
CA2736799A1 (en) 2008-08-25 2010-03-11 Burnham Institute For Medical Research Conserved hemagglutinin epitope, antibodies to the epitope, and methods of use
WO2010146578A2 (en) 2009-06-14 2010-12-23 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
SG195055A1 (en) 2011-06-07 2013-12-30 Polyphor Ag Beta - hairpin peptidomimetics as cxc4 antagonists
EP2841084B1 (de) 2012-04-24 2018-05-30 Biokine Therapeutics Ltd. Cxcr4 antagonist peptid zur verwendung in der behandlung von lungenkrebs
CN104072579B (zh) * 2014-06-11 2017-01-25 南方医科大学 具有抗菌抗病毒活性的小分子肽及其活性修饰物
EP3943098A3 (de) 2015-07-16 2022-05-11 Biokine Therapeutics Ltd. Zusammensetzungen und verfahren zur behandlung von krebs
KR102033920B1 (ko) 2016-02-23 2019-10-18 바이오라인알엑스 리미티드 급성 골수성 백혈병을 치료하는 방법
RU2658781C1 (ru) * 2017-12-28 2018-06-22 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид, обладающий противоопухолевой активностью
CN110841607B (zh) * 2019-11-22 2020-07-24 中国科学院地质与地球物理研究所 一种超低本底金特效树脂及其制备和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337781C (en) * 1987-08-21 1995-12-19 Takanori Nakamura Polypeptide from horseshoe crab exhibiting affinity for lipopolysaccharide and method of preparation
JP2641742B2 (ja) * 1988-08-18 1997-08-20 マルハ株式会社 新規ペプチド及び抗菌剤
JP2641744B2 (ja) * 1988-08-18 1997-08-20 マルハ株式会社 新規ペプチド及び抗菌剤
JP2798711B2 (ja) * 1988-09-26 1998-09-17 生化学工業株式会社 ポリペプチド系抗ウィルス剤
DE69115878T2 (de) * 1990-09-11 1996-06-05 Seikagaku Kogyo Co Ltd Neue polypeptide und damit hergestellte anti-hiv medikamente
JP3266311B2 (ja) * 1991-05-02 2002-03-18 生化学工業株式会社 新規ポリペプチドおよびこれを用いる抗hiv剤
HUT61036A (en) * 1991-05-02 1992-11-30 Seikagaku Kogyo Co Ltd Process for producing new polypeptides capable of linking to lipopolysaccharides and pharmaceutical compositions comprising same as active ingredients
JP2500194B2 (ja) 1993-08-10 1996-05-29 株式会社ヴァンドームヤマダ 商品発注システム

Also Published As

Publication number Publication date
HU217442B (hu) 2000-01-28
FI952900A (fi) 1995-06-13
AU682405B2 (en) 1997-10-02
ATE177114T1 (de) 1999-03-15
FI952900A0 (fi) 1995-06-13
CN1116427A (zh) 1996-02-07
EP0677061B1 (de) 1999-03-03
NO952321L (no) 1995-08-09
CN1038841C (zh) 1998-06-24
CZ153395A3 (en) 1995-12-13
DE69416824D1 (de) 1999-04-08
NO952321D0 (no) 1995-06-13
RU2136696C1 (ru) 1999-09-10
EP0677061A1 (de) 1995-10-18
JPH08504837A (ja) 1996-05-28
HUT72974A (en) 1996-06-28
NZ274560A (en) 1998-03-25
KR100208873B1 (ko) 1999-07-15
WO1995010534A1 (en) 1995-04-20
AU7862894A (en) 1995-05-04
US5776899A (en) 1998-07-07
RU95112539A (ru) 1997-06-27
CZ287239B6 (en) 2000-10-11
ZA948005B (en) 1996-02-06
HU9501719D0 (en) 1995-08-28
CA2151283A1 (en) 1995-04-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: YAMAMOTO, NAOKI, TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee