DE69333269T2 - Expressionssystem in säugetieren für hcv-proteine - Google Patents

Expressionssystem in säugetieren für hcv-proteine Download PDF

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Publication number
DE69333269T2
DE69333269T2 DE69333269T DE69333269T DE69333269T2 DE 69333269 T2 DE69333269 T2 DE 69333269T2 DE 69333269 T DE69333269 T DE 69333269T DE 69333269 T DE69333269 T DE 69333269T DE 69333269 T2 DE69333269 T2 DE 69333269T2
Authority
DE
Germany
Prior art keywords
hcv
phcv
antibody
antibodies
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333269T
Other languages
German (de)
English (en)
Other versions
DE69333269D1 (de
Inventor
M. James CASEY
L. Suzanne BODE
J. Billy ZECK
Julie Yamaguchi
E. Donald FRAIL
M. Suresh DESAI
G. Sushil DEVARE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69333269D1 publication Critical patent/DE69333269D1/de
Application granted granted Critical
Publication of DE69333269T2 publication Critical patent/DE69333269T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69333269T 1992-01-31 1993-01-29 Expressionssystem in säugetieren für hcv-proteine Expired - Lifetime DE69333269T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83002492A 1992-01-31 1992-01-31
US830024 1992-01-31
PCT/US1993/000907 WO1993015193A1 (en) 1992-01-31 1993-01-29 Mammalian expression systems for hcv proteins

Publications (2)

Publication Number Publication Date
DE69333269D1 DE69333269D1 (de) 2003-12-04
DE69333269T2 true DE69333269T2 (de) 2004-07-29

Family

ID=25256134

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333269T Expired - Lifetime DE69333269T2 (de) 1992-01-31 1993-01-29 Expressionssystem in säugetieren für hcv-proteine

Country Status (9)

Country Link
US (2) US5667992A (enExample)
EP (1) EP0627000B1 (enExample)
JP (1) JP3439209B2 (enExample)
AU (1) AU666176B2 (enExample)
CA (1) CA2129733C (enExample)
DE (1) DE69333269T2 (enExample)
ES (1) ES2210235T3 (enExample)
TW (1) TW239147B (enExample)
WO (1) WO1993015193A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
US5514539A (en) 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5610009A (en) * 1994-01-28 1997-03-11 Abbott Laboratories Mammalian expression systems for hepatitis C virus envelope genes
SG71728A1 (en) * 1994-07-29 2000-04-18 Innogenetics Nv Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use
DE69533167D1 (de) * 1994-10-05 2004-07-22 Apollon Inc Impfstoffe gegen den hepatitis b und c virus
US6235888B1 (en) * 1994-10-05 2001-05-22 The General Hospital Corporation Hepatitis C virus vaccine
RU2189254C2 (ru) * 1995-06-06 2002-09-20 Америкэн Хоум Продактс Корпорэйшн Вакцины против вирусов гепатита
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US7235394B1 (en) 1995-08-29 2007-06-26 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
EP0947525A1 (en) 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
US7108855B2 (en) 1998-06-24 2006-09-19 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
DE19856261C1 (de) * 1998-12-07 2000-03-30 Hoechst Marion Roussel De Gmbh Aß-Peptid Screening Assay
US7244721B2 (en) * 2000-07-21 2007-07-17 Schering Corporation Peptides as NS3-serine protease inhibitors of hepatitis C virus
WO2002008187A1 (en) * 2000-07-21 2002-01-31 Schering Corporation Novel peptides as ns3-serine protease inhibitors of hepatitis c virus
CN1498224A (zh) * 2000-07-21 2004-05-19 ���鹫˾ 用作丙型肝炎病毒ns3-丝氨酸蛋白酶抑制剂的新型肽
AR029851A1 (es) * 2000-07-21 2003-07-16 Dendreon Corp Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
US7101561B2 (en) 2000-12-01 2006-09-05 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
TW584950B (en) 2001-12-31 2004-04-21 Megic Corp Chip packaging structure and process thereof
TW503496B (en) 2001-12-31 2002-09-21 Megic Corp Chip packaging structure and manufacturing process of the same
TW544882B (en) * 2001-12-31 2003-08-01 Megic Corp Chip package structure and process thereof
US6673698B1 (en) 2002-01-19 2004-01-06 Megic Corporation Thin film semiconductor package utilizing a glass substrate with composite polymer/metal interconnect layers
WO2009020628A1 (en) * 2007-08-06 2009-02-12 Epiphany Biosciences, Inc. Diagnosis of kaposi's sarcoma-associated herpesvirus (kshv) infection
US20110135674A1 (en) 2009-06-30 2011-06-09 Abbott Laboratories Markers of XMRV Infection and Uses Thereof
WO2011024875A1 (ja) * 2009-08-28 2011-03-03 財団法人 東京都医学研究機構 C型肝炎ウイルスの新規株由来のポリヌクレオチド及びその利用
CN109232721B (zh) * 2018-09-26 2021-06-29 广州市第八人民医院 Hcv包膜蛋白高度保守区域的肽段418-429及其用途
US20230210968A1 (en) * 2020-06-11 2023-07-06 Massachusetts Institute Of Technology Ribonucleoprotein approach to boost the sting signaling for cancer immunotherapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU48038B (sh) * 1987-11-18 1996-10-18 Chiron Corp. Postupak za dijagnostiku ne-a, ne-v hepatitisa
IE62868B1 (en) * 1987-11-18 1995-03-08 Chiron Corp Hepatitis C virus
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
SK285623B6 (sk) * 1990-11-08 2007-05-03 Chiron Corporation Spôsob produkcie asialoglykoproteínu hepatitis C vírusu

Also Published As

Publication number Publication date
TW239147B (enExample) 1995-01-21
AU3604993A (en) 1993-09-01
CA2129733A1 (en) 1993-08-01
DE69333269D1 (de) 2003-12-04
EP0627000A4 (en) 1997-07-02
EP0627000B1 (en) 2003-10-29
JP3439209B2 (ja) 2003-08-25
US5667992A (en) 1997-09-16
JPH07503614A (ja) 1995-04-20
WO1993015193A1 (en) 1993-08-05
AU666176B2 (en) 1996-02-01
ES2210235T3 (es) 2004-07-01
US5854001A (en) 1998-12-29
EP0627000A1 (en) 1994-12-07
CA2129733C (en) 2006-10-31

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