DE69332374T2 - Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen - Google Patents

Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Info

Publication number
DE69332374T2
DE69332374T2 DE69332374T DE69332374T DE69332374T2 DE 69332374 T2 DE69332374 T2 DE 69332374T2 DE 69332374 T DE69332374 T DE 69332374T DE 69332374 T DE69332374 T DE 69332374T DE 69332374 T2 DE69332374 T2 DE 69332374T2
Authority
DE
Germany
Prior art keywords
cells
compositions
devices
human stem
breeding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332374T
Other languages
English (en)
Other versions
DE69332374D1 (de
Inventor
O Palsson
G Emerson
M Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Application granted granted Critical
Publication of DE69332374D1 publication Critical patent/DE69332374D1/de
Publication of DE69332374T2 publication Critical patent/DE69332374T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69332374T 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen Expired - Lifetime DE69332374T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84596992A 1992-03-04 1992-03-04
PCT/US1993/001803 WO1993018132A1 (en) 1992-03-04 1993-03-04 Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells

Publications (2)

Publication Number Publication Date
DE69332374D1 DE69332374D1 (de) 2002-11-14
DE69332374T2 true DE69332374T2 (de) 2003-06-12

Family

ID=25296563

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332374T Expired - Lifetime DE69332374T2 (de) 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Country Status (8)

Country Link
EP (1) EP0629236B1 (de)
JP (1) JPH07504570A (de)
KR (1) KR100271284B1 (de)
AT (1) ATE225847T1 (de)
AU (1) AU685743B2 (de)
CA (1) CA2131385C (de)
DE (1) DE69332374T2 (de)
WO (1) WO1993018132A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202018000370U1 (de) 2018-01-24 2018-04-12 Zellwerk Gmbh Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE202018004857U1 (de) 2018-10-20 2019-01-14 Zellwerk Gmbh Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen
DE102018000561A1 (de) 2018-01-24 2019-07-25 Zellwerk Gmbh Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben

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US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
AU687531B2 (en) * 1994-03-11 1998-02-26 Baxter International Inc. Flow-through bioreactor with grooves for cell retention
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
US5843766A (en) * 1995-06-07 1998-12-01 Advanced Tissue Sciences, Inc. Apparatus for the growth and packaging of three dimensional tissue cultures
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
WO1996039992A1 (en) * 1995-06-07 1996-12-19 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing replacement cartilage tissue constructs
US5763267A (en) * 1996-04-16 1998-06-09 Advanced Tissue Sciences Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
AU7172598A (en) * 1997-05-07 1998-11-27 Baxter International Inc. Method and apparatus for high volume production of viral particles
FR2771421B1 (fr) * 1997-11-27 2001-05-04 Bertin & Cie Dispositif d'amplification de cellules hematopoietiques et ses applications
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
US7063942B2 (en) * 2000-10-06 2006-06-20 Victor Krstec System and method to simulate hemodynamics
DE10128810B4 (de) * 2001-06-18 2013-11-07 Pan-Biotech Gmbh Einrichtung zur Kultivierung von Zellen, insbesondere menschlicher oder tierischer Zellen
CA2853267C (en) * 2002-04-08 2018-06-26 Octane Biotech Inc. Automated tissue engineering system comprising sensors linked to a microprocessor
DE10223536A1 (de) * 2002-05-27 2003-12-18 J Hinrich Peters Verfahren zur Trennung nicht-adhärenter Zellen von adhärenten Zellen
WO2004033615A1 (de) 2002-09-16 2004-04-22 Pan-Biotech Gmbh Verfahren zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
EP1773981A1 (de) * 2004-07-12 2007-04-18 Sorin Group Italia S.R.L. Vorrichtung und verfahren zur anzucht menschlicher zellen
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
WO2008028241A1 (en) * 2006-09-06 2008-03-13 The University Of Queensland Microbioreactor
EP2128242B1 (de) * 2008-02-22 2018-05-16 CoorsTek KK Zellkulturmodul
EP2449095A1 (de) * 2009-07-02 2012-05-09 Anthrogenesis Corporation Verfahren zur produktion von erythrozyten ohne feederzellen
GB0914195D0 (en) * 2009-08-13 2009-09-16 Plasticell Ltd Vessel for culturing cells
CN103764190B (zh) 2011-06-15 2019-03-08 查尔斯斯塔克布料实验室公司 与仿生细胞化肾单位有关的系统、方法和装置
US20120322097A1 (en) * 2011-06-15 2012-12-20 The Charles Stark Draper Laboratory, Inc. Device and method for culturing cells in a biomimetic environment
EP2814951B1 (de) 2012-02-13 2019-04-03 Gamida-Cell Ltd. Kultivierung mesenchymaler stammzellen
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
JP5828823B2 (ja) * 2012-09-28 2015-12-09 クアーズテック株式会社 細胞培養モジュール及び細胞培養方法
WO2014061675A1 (ja) * 2012-10-17 2014-04-24 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
JP2014124097A (ja) * 2012-12-25 2014-07-07 Hitachi High-Technologies Corp 核酸分析用カートリッジ及び核酸分析装置
WO2017096207A1 (en) * 2015-12-03 2017-06-08 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Modular bioreactor for culture of biopaper based tissues
CN109843417B (zh) 2016-08-21 2022-09-02 艾德瓦生物技术股份有限公司 生物反应器及其使用方法
US20230242864A1 (en) * 2022-01-31 2023-08-03 Sciperio, Inc In-time storage of manufactured cells for medical cellular therapy grown and differentiated in bioreactors

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DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
ZA839242B (en) * 1982-12-15 1984-09-26 Bio Response Inc A method and system for culturing and treating substances disposed in a flowing culture fluid
US5135853A (en) * 1983-07-22 1992-08-04 Rensselaer Polytechnic Institute Three compartment bioreactor and method of use
DE3409501A1 (de) * 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen
US4894342A (en) * 1986-05-12 1990-01-16 C. D. Medical, Inc. Bioreactor system
US4861483A (en) * 1986-07-07 1989-08-29 Cornell Research Foundation, Inc. Apparatus and process to eliminate diffusional limitations in a membrane biological reactor by pressure cycling
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
DK0477290T3 (da) * 1989-06-15 1997-07-21 Univ Michigan Fremgangsmåder, sammensætninger og indretninger til dyrkning af celler
ATE143999T1 (de) * 1991-06-19 1996-10-15 Endotronics Inc Zellkultur apparat
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202018000370U1 (de) 2018-01-24 2018-04-12 Zellwerk Gmbh Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE102018000561A1 (de) 2018-01-24 2019-07-25 Zellwerk Gmbh Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
EP3517600A1 (de) 2018-01-24 2019-07-31 Zellwerk GmbH Mäander-bioreaktor und verfahren für die isolierung und vermehrung von zellen aus gewebeteilen von tumoren, metastasen und anderen geweben
DE202018004857U1 (de) 2018-10-20 2019-01-14 Zellwerk Gmbh Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen
WO2020078498A1 (de) 2018-10-20 2020-04-23 Zellwerk Gmbh Mäander-perfusions-bioreaktor für die differenzierung, aktivierung, stimulierung und abtrennung von zellen

Also Published As

Publication number Publication date
KR100271284B1 (ko) 2000-11-01
JPH07504570A (ja) 1995-05-25
ATE225847T1 (de) 2002-10-15
EP0629236B1 (de) 2002-10-09
CA2131385A1 (en) 1993-09-16
DE69332374D1 (de) 2002-11-14
EP0629236A1 (de) 1994-12-21
EP0629236A4 (de) 1997-06-04
AU685743B2 (en) 1998-01-29
CA2131385C (en) 2008-07-15
AU3914893A (en) 1993-10-05
WO1993018132A1 (en) 1993-09-16

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