DE69325643T2 - Zusammensetzung zur raucherentwöhnung - Google Patents
Zusammensetzung zur raucherentwöhnungInfo
- Publication number
- DE69325643T2 DE69325643T2 DE69325643T DE69325643T DE69325643T2 DE 69325643 T2 DE69325643 T2 DE 69325643T2 DE 69325643 T DE69325643 T DE 69325643T DE 69325643 T DE69325643 T DE 69325643T DE 69325643 T2 DE69325643 T2 DE 69325643T2
- Authority
- DE
- Germany
- Prior art keywords
- composition
- pct
- sec
- pharmaceutically acceptable
- range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000391 smoking effect Effects 0.000 title abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 2
- 241000208125 Nicotiana Species 0.000 abstract 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 2
- 229960002715 nicotine Drugs 0.000 abstract 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000002850 nasal mucosa Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000779 smoke Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Confectionery (AREA)
- Cosmetics (AREA)
- Manufacture Of Tobacco Products (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929200047A GB9200047D0 (en) | 1992-01-03 | 1992-01-03 | Nicotine-containing nasal spray |
PCT/CA1993/000003 WO1993012764A1 (en) | 1992-01-03 | 1993-01-04 | Composition to help stop smoking |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69325643D1 DE69325643D1 (de) | 1999-08-19 |
DE69325643T2 true DE69325643T2 (de) | 2000-02-10 |
Family
ID=10708064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69325643T Expired - Lifetime DE69325643T2 (de) | 1992-01-03 | 1993-01-04 | Zusammensetzung zur raucherentwöhnung |
Country Status (21)
Country | Link |
---|---|
US (1) | US5656255A (de) |
EP (1) | EP0619729B1 (de) |
JP (1) | JP3830158B2 (de) |
KR (2) | KR950700055A (de) |
AT (1) | ATE182070T1 (de) |
AU (1) | AU664415B2 (de) |
CA (1) | CA2127253C (de) |
CZ (1) | CZ294555B6 (de) |
DE (1) | DE69325643T2 (de) |
DK (1) | DK0619729T3 (de) |
ES (1) | ES2135460T3 (de) |
FI (1) | FI111049B (de) |
GB (1) | GB9200047D0 (de) |
GR (1) | GR3031075T3 (de) |
HU (1) | HUT73247A (de) |
NO (1) | NO308123B1 (de) |
NZ (1) | NZ246533A (de) |
RU (1) | RU2118897C1 (de) |
SK (1) | SK282336B6 (de) |
UA (1) | UA37201C2 (de) |
WO (1) | WO1993012764A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9310412D0 (en) * | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
AUPM835394A0 (en) * | 1994-09-23 | 1994-10-13 | King, Michael G. Dr. | Method for controlling or eliminating the need to smoke tobacco, and for treating ailments which may lead to the said need |
JPH11507810A (ja) * | 1995-06-05 | 1999-07-13 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | Gタンパク質副甲状腺ホルモンレセプターhltdg74 |
CA2231968A1 (en) * | 1998-03-11 | 1999-09-11 | Smoke-Stop, A Partnership Consisting Of Art Slutsky | Method of producing a nicotine medicament |
GB9806937D0 (en) | 1998-03-31 | 1998-05-27 | Procter & Gamble | A spray device |
CA2359813C (en) | 2000-10-24 | 2008-04-22 | Richard L. Jones | Nicotine mucosal spray |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
SE0102197D0 (sv) * | 2001-06-20 | 2001-06-20 | Pharmacia Ab | New product and use and manufacture thereof |
SE521512C2 (sv) * | 2001-06-25 | 2003-11-11 | Niconovum Ab | Anordning för administrering av en substans till främre delen av en individs munhåla |
DE60105820D1 (de) * | 2001-10-22 | 2004-10-28 | Pera Ivo E | Zusammensetzung zur Reduzierung oder Entwöhnung von Nikotinabhängigkeit |
SE0104388D0 (sv) * | 2001-12-27 | 2001-12-27 | Pharmacia Ab | New formulation and use and manufacture thereof |
US20030159702A1 (en) * | 2002-01-21 | 2003-08-28 | Lindell Katarina E.A. | Formulation and use manufacture thereof |
US20030171408A1 (en) * | 2002-03-11 | 2003-09-11 | Caplan Jay L. | Therapeutic method of delivering a medicament to avoid irritating effects on membranes of user |
US7767698B2 (en) | 2002-06-03 | 2010-08-03 | Mcneil Ab | Formulation and use thereof |
SE0201669D0 (sv) * | 2002-06-03 | 2002-06-03 | Pharmacia Ab | New formulation and use thereof |
US20040002520A1 (en) * | 2002-07-01 | 2004-01-01 | Soderlund Patrick L. | Composition and method for cessation of Nicotine cravings |
US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
DE60313216T2 (de) * | 2002-12-20 | 2008-01-03 | Niconovum Ab | Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose |
CA2526432A1 (en) | 2003-05-21 | 2004-12-02 | Alexza Pharmaceuticals, Inc. | Self-contained heating unit and drug-supply unit employing same |
US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
WO2006031856A2 (en) | 2004-09-13 | 2006-03-23 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
US7766018B2 (en) * | 2004-09-30 | 2010-08-03 | Smoke-Break, Inc. | Device and composition for reducing the incidence of tobacco smoking |
US8322350B2 (en) | 2004-12-30 | 2012-12-04 | Philip Morris Usa Inc. | Aerosol generator |
US8323683B2 (en) | 2005-05-18 | 2012-12-04 | Mcneil-Ppc, Inc. | Flavoring of drug-containing chewing gums |
JP5694645B2 (ja) | 2006-03-16 | 2015-04-01 | ニコノヴァム エービーNiconovum Ab | 改善された嗅ぎたばこ組成物 |
US20080216828A1 (en) | 2007-03-09 | 2008-09-11 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
EP1977746B8 (de) * | 2007-04-02 | 2014-09-24 | Parkinson's Institute | Verfahren und Zusammensetzung zur Verringerung der Nebenwirkungen von therapeutischen Behandlungen |
EP2218760B1 (de) * | 2007-11-30 | 2015-09-02 | Japan Tobacco Inc. | Aerosolbildende lösung für einen aerosolaspirator |
EP2233134A1 (de) | 2009-03-27 | 2010-09-29 | McNeil AB | Mehrteilige intraorale Darreichungsform mit organoleptischen Eigenschaften |
WO2011087393A1 (ru) * | 2010-01-18 | 2011-07-21 | Общество С Ограниченной Ответственностью "Вегавольт" | Композиция растительного происхождения, предназначенная для вдыхания дыма, образующегося при ее сжигании |
US20110268809A1 (en) | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
US20110274628A1 (en) | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
CA2841785A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
US10679516B2 (en) | 2015-03-12 | 2020-06-09 | Morningside Venture Investments Limited | Craving input and support system |
US10532046B2 (en) | 2015-12-03 | 2020-01-14 | Niconovum Usa, Inc. | Multi-phase delivery compositions and products incorporating such compositions |
US20170165252A1 (en) | 2015-12-10 | 2017-06-15 | Niconovum Usa Inc. | Protein-enriched therapeutic composition |
WO2017149534A1 (en) * | 2016-02-29 | 2017-09-08 | Nicogen Ltd. | Nicotine formulation and aerosols |
WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
SE541358C2 (en) | 2017-05-30 | 2019-08-13 | Enorama Pharma Ab | Nicotine-containing chewing gum compositions |
US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
BR112020025604A2 (pt) | 2018-06-15 | 2021-03-23 | R.J. Reynolds Tobacco Company | purificação de nicotina |
CZ309558B6 (cs) * | 2021-05-25 | 2023-04-12 | Consumer Brands International s.r.o. | Náplň nikotinového prostředku, zejména nikotinového sáčku a způsob jeho výroby |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2030862A (en) * | 1978-04-10 | 1980-04-16 | Smith A | A composition for treating drug addiction such as smoking nicotine-containing products |
DE3241437A1 (de) * | 1982-11-10 | 1984-05-10 | Ferdinand Prof. Dr.med. 6901 Wilhelmsfeld Schmidt | Mittel zum zwecke der raucherentwoehnung und/oder fuer nebenwirkungsfreien nikotingenuss bei suchtrauchern |
GB2133691B (en) * | 1983-01-21 | 1986-05-21 | Leo Ab | Smoking substitutes for nasal administration |
GB8301659D0 (en) * | 1983-01-21 | 1983-02-23 | Leo Ab | Smoking substitutes |
US4953572A (en) * | 1985-04-25 | 1990-09-04 | Rose Jed E | Method and apparatus for aiding in the reduction of incidence of tobacco smoking |
US4920989A (en) * | 1985-04-25 | 1990-05-01 | Regents Of The University Of California | Method and apparatus for aiding in the reduction of incidence of tobacco smoking |
US4715387A (en) * | 1985-08-23 | 1987-12-29 | The Regents Of The Univ. Of California | Aerosol for use in the reduction of tobacco smoking |
SE8601351D0 (sv) * | 1986-03-24 | 1986-03-24 | Nilsson Sven Erik | Styrd administration av fysiologiskt aktiva emnen |
GB8614805D0 (en) * | 1986-06-18 | 1986-07-23 | British American Tobacco Co | Aerosol device |
-
1992
- 1992-01-03 GB GB929200047A patent/GB9200047D0/en active Pending
-
1993
- 1993-01-04 WO PCT/CA1993/000003 patent/WO1993012764A1/en active IP Right Grant
- 1993-01-04 EP EP93901989A patent/EP0619729B1/de not_active Expired - Lifetime
- 1993-01-04 SK SK796-94A patent/SK282336B6/sk unknown
- 1993-01-04 RU RU94040387A patent/RU2118897C1/ru active
- 1993-01-04 KR KR1019940702316A patent/KR950700055A/ko not_active IP Right Cessation
- 1993-01-04 DK DK93901989T patent/DK0619729T3/da active
- 1993-01-04 ES ES93901989T patent/ES2135460T3/es not_active Expired - Lifetime
- 1993-01-04 DE DE69325643T patent/DE69325643T2/de not_active Expired - Lifetime
- 1993-01-04 US US08/256,312 patent/US5656255A/en not_active Expired - Lifetime
- 1993-01-04 CA CA002127253A patent/CA2127253C/en not_active Expired - Lifetime
- 1993-01-04 HU HU9402003A patent/HUT73247A/hu unknown
- 1993-01-04 CZ CZ19941608A patent/CZ294555B6/cs not_active IP Right Cessation
- 1993-01-04 AT AT93901989T patent/ATE182070T1/de not_active IP Right Cessation
- 1993-01-04 JP JP51133293A patent/JP3830158B2/ja not_active Expired - Lifetime
- 1993-01-04 UA UA94075668A patent/UA37201C2/uk unknown
- 1993-01-04 KR KR940702316A patent/KR100317426B1/ko active
- 1993-01-04 NZ NZ246533A patent/NZ246533A/en not_active IP Right Cessation
- 1993-01-04 AU AU33403/93A patent/AU664415B2/en not_active Expired
-
1994
- 1994-07-01 FI FI943173A patent/FI111049B/fi not_active IP Right Cessation
- 1994-07-01 NO NO942502A patent/NO308123B1/no unknown
-
1999
- 1999-08-26 GR GR990402158T patent/GR3031075T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5656255A (en) | 1997-08-12 |
NO942502L (no) | 1994-09-02 |
NO308123B1 (no) | 2000-07-31 |
CA2127253A1 (en) | 1993-07-08 |
CZ294555B6 (cs) | 2005-02-16 |
HUT73247A (en) | 1996-07-29 |
ATE182070T1 (de) | 1999-07-15 |
NO942502D0 (no) | 1994-07-01 |
JPH07504164A (ja) | 1995-05-11 |
WO1993012764A1 (en) | 1993-07-08 |
FI943173A0 (fi) | 1994-07-01 |
FI111049B (fi) | 2003-05-30 |
FI943173A (fi) | 1994-09-01 |
SK282336B6 (sk) | 2002-01-07 |
CA2127253C (en) | 1999-09-21 |
NZ246533A (en) | 1996-04-26 |
EP0619729B1 (de) | 1999-07-14 |
KR950700055A (ko) | 1995-01-16 |
ES2135460T3 (es) | 1999-11-01 |
GR3031075T3 (en) | 1999-12-31 |
DK0619729T3 (da) | 2000-04-17 |
JP3830158B2 (ja) | 2006-10-04 |
RU94040387A (ru) | 1996-10-20 |
UA37201C2 (uk) | 2001-05-15 |
AU3340393A (en) | 1993-07-28 |
KR100317426B1 (de) | 2001-11-30 |
RU2118897C1 (ru) | 1998-09-20 |
CZ160894A3 (en) | 1995-09-13 |
AU664415B2 (en) | 1995-11-16 |
HU9402003D0 (en) | 1994-09-28 |
GB9200047D0 (en) | 1992-02-26 |
EP0619729A1 (de) | 1994-10-19 |
DE69325643D1 (de) | 1999-08-19 |
SK79694A3 (en) | 1995-06-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: PFIZER HEALTH AB, STOCKHOLM, SE |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: PFIZER CONSUMER HEALTHCARE HELTH AB, STOCKHOLM, SE |
|
R071 | Expiry of right |
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