DE69318418T2 - Pharmazeutische zusammensetzungen, die 5-ht 1-rezeptoragonisten und absorptionsverstärker enthalten - Google Patents

Pharmazeutische zusammensetzungen, die 5-ht 1-rezeptoragonisten und absorptionsverstärker enthalten

Info

Publication number
DE69318418T2
DE69318418T2 DE69318418T DE69318418T DE69318418T2 DE 69318418 T2 DE69318418 T2 DE 69318418T2 DE 69318418 T DE69318418 T DE 69318418T DE 69318418 T DE69318418 T DE 69318418T DE 69318418 T2 DE69318418 T2 DE 69318418T2
Authority
DE
Germany
Prior art keywords
receptoragonists
pharmaceutical compositions
compositions containing
absorption
amplifiers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69318418T
Other languages
English (en)
Other versions
DE69318418D1 (de
Inventor
Christopher Doherty
Renu Gambhir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Inc
Original Assignee
Glaxo Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Canada Inc filed Critical Glaxo Canada Inc
Application granted granted Critical
Publication of DE69318418D1 publication Critical patent/DE69318418D1/de
Publication of DE69318418T2 publication Critical patent/DE69318418T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
DE69318418T 1992-05-28 1993-05-24 Pharmazeutische zusammensetzungen, die 5-ht 1-rezeptoragonisten und absorptionsverstärker enthalten Expired - Fee Related DE69318418T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929211277A GB9211277D0 (en) 1992-05-28 1992-05-28 Pharmaceutical compositions
PCT/EP1993/001301 WO1993024116A1 (en) 1992-05-28 1993-05-24 Pharmaceutical compositions comprising 5-ht1 receptor agonists and absorption enhancers

Publications (2)

Publication Number Publication Date
DE69318418D1 DE69318418D1 (de) 1998-06-10
DE69318418T2 true DE69318418T2 (de) 1998-09-24

Family

ID=10716139

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69318418T Expired - Fee Related DE69318418T2 (de) 1992-05-28 1993-05-24 Pharmazeutische zusammensetzungen, die 5-ht 1-rezeptoragonisten und absorptionsverstärker enthalten

Country Status (8)

Country Link
EP (1) EP0671908B1 (de)
JP (1) JPH07507065A (de)
AT (1) ATE165737T1 (de)
CA (1) CA2136845A1 (de)
DE (1) DE69318418T2 (de)
ES (1) ES2116452T3 (de)
GB (1) GB9211277D0 (de)
WO (1) WO1993024116A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2434297A (en) * 1996-05-23 1997-12-09 Alcon Laboratories, Inc. The use of 5-ht1b/1d agonists to treat ocular pain

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8300699A1 (es) 1980-08-12 1982-11-01 Glaxo Group Ltd Procedimiento para la preparacion de derivados del indol.
ZW19381A1 (en) 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
GR79215B (de) 1982-06-07 1984-10-22 Glaxo Group Ltd
US4615885A (en) 1983-11-01 1986-10-07 Terumo Kabushiki Kaisha Pharmaceutical composition containing urokinase
GB8332437D0 (en) 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
HU196752B (en) 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB2162522B (en) 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
NL8503337A (nl) 1984-12-04 1986-07-01 Glaxo Group Ltd Indoolderivaten.
GB8431426D0 (en) 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
DE3678805D1 (de) 1985-11-08 1991-05-23 Glaxo Group Ltd Indolderivate.
GB8530507D0 (en) 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600397D0 (en) 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600398D0 (en) 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8601959D0 (en) 1986-01-28 1986-03-05 Glaxo Group Ltd Indole derivatives
GB8607824D0 (en) 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
GB8614287D0 (en) 1986-06-12 1986-07-16 Glaxo Group Ltd Chemical compounds
GB8615599D0 (en) 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
PT88255B (pt) 1987-08-13 1995-03-01 Glaxo Group Ltd Processo para a preparacao de derivados do indole
GB8719167D0 (en) 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8903036D0 (en) 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds
IL96891A0 (en) 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
HUT57185A (en) 1990-03-21 1991-11-28 Merrell Dow Pharma Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them
EP0450238A1 (de) 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Verbindungen für die Behandlung von Migräne
MC2210A1 (fr) 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
CA2043709C (en) 1990-06-29 2002-01-22 David W. Smith Antimigraine alkoxypyrimidine derivatives
US5189179A (en) 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
AU651637B2 (en) 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
DE4041465A1 (de) 1990-12-22 1992-06-25 Basf Ag 10-cyanmethylen-4-(piperazin-1-yl)-pyrrolo (4,3-e)benzoazepinen zur bekaempfung der migraene
DE4041463A1 (de) 1990-12-22 1992-06-25 Basf Ag 5-cyanmethylen-10-(piperazin-1-yl)-dibenzo(a,d)cycloheptene zur bekaempfung der migraene
EP0494774A1 (de) 1991-01-11 1992-07-15 MERCK SHARP & DOHME LTD. Indazol-substituierte 5-Kettenglieder heteroaromatische Verbindungen
SK278998B6 (sk) 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
TW263508B (de) 1991-02-12 1995-11-21 Pfizer
GB9104136D0 (en) 1991-02-27 1991-04-17 Merck Sharp & Dohme Therapeutic agents
US5244911A (en) 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5244912A (en) 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
JPH06508352A (ja) 1991-06-21 1994-09-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 門脈圧亢進症および片頭痛の治療用のテトラヒドロベンズアゼピン誘導体の使用
JPH06508354A (ja) 1991-06-21 1994-09-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー トリプタミン類似体、その合成法およびその５−ｈｔ↓１様または５−ｈｔ↓２受容体作用物質としての使用
GB9113802D0 (en) 1991-06-26 1991-08-14 Smithkline Beecham Plc Medicaments

Also Published As

Publication number Publication date
ATE165737T1 (de) 1998-05-15
ES2116452T3 (es) 1998-07-16
WO1993024116A1 (en) 1993-12-09
JPH07507065A (ja) 1995-08-03
DE69318418D1 (de) 1998-06-10
CA2136845A1 (en) 1993-12-09
GB9211277D0 (en) 1992-07-15
EP0671908A1 (de) 1995-09-20
EP0671908B1 (de) 1998-05-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee