DE69316751T2 - Azlaktonfunktionen aufweisende substrate, hornhautprothesen und ihre verwendung - Google Patents
Azlaktonfunktionen aufweisende substrate, hornhautprothesen und ihre verwendungInfo
- Publication number
- DE69316751T2 DE69316751T2 DE69316751T DE69316751T DE69316751T2 DE 69316751 T2 DE69316751 T2 DE 69316751T2 DE 69316751 T DE69316751 T DE 69316751T DE 69316751 T DE69316751 T DE 69316751T DE 69316751 T2 DE69316751 T2 DE 69316751T2
- Authority
- DE
- Germany
- Prior art keywords
- azlakton
- functional substrates
- corneal prostheses
- prostheses
- corneal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/15—Heterocyclic compounds having oxygen in the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/15—Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/903,367 US5292514A (en) | 1992-06-24 | 1992-06-24 | Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof |
PCT/US1993/004554 WO1994000165A2 (en) | 1992-06-24 | 1993-05-13 | Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69316751D1 DE69316751D1 (de) | 1998-03-05 |
DE69316751T2 true DE69316751T2 (de) | 1998-09-10 |
Family
ID=25417387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69316751T Expired - Fee Related DE69316751T2 (de) | 1992-06-24 | 1993-05-13 | Azlaktonfunktionen aufweisende substrate, hornhautprothesen und ihre verwendung |
Country Status (6)
Country | Link |
---|---|
US (1) | US5292514A (de) |
EP (1) | EP0647143B1 (de) |
JP (1) | JPH07508196A (de) |
CA (1) | CA2136728A1 (de) |
DE (1) | DE69316751T2 (de) |
WO (1) | WO1994000165A2 (de) |
Families Citing this family (92)
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US5344701A (en) * | 1992-06-09 | 1994-09-06 | Minnesota Mining And Manufacturing Company | Porous supports having azlactone-functional surfaces |
US6197056B1 (en) * | 1992-07-15 | 2001-03-06 | Ras Holding Corp. | Segmented scleral band for treatment of presbyopia and other eye disorders |
US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
GB9310241D0 (en) * | 1993-05-18 | 1993-06-30 | Unilever Plc | Cosmetic treatment of substrates |
US5408002A (en) * | 1993-09-09 | 1995-04-18 | Minnesota Mining And Manufacturing Company | Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both |
US5420197A (en) * | 1994-01-13 | 1995-05-30 | Hydromer, Inc. | Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives |
US5476665A (en) * | 1994-04-13 | 1995-12-19 | Minnesota Mining And Manufacturing Company | Azlactone functional particles incorporated in a membrane formed by solvent phase inversion |
US5561097A (en) * | 1994-04-28 | 1996-10-01 | Minnesota Mining And Manufacturing Company | Method of controlling density of ligand coupled onto supports and products produced therefrom |
US5510421A (en) * | 1994-05-26 | 1996-04-23 | Minnesota Mining And Manufacturing Company | Azlactone-functional membranes and methods of preparing and using same |
US5714632A (en) * | 1995-11-13 | 1998-02-03 | Minnesota Mining And Manufacturing Company | Azlactone-based surfactants |
US5840106A (en) * | 1995-11-13 | 1998-11-24 | Minnesota Mining And Manufacturing Company | Water-based pigmented inks |
AR009439A1 (es) | 1996-12-23 | 2000-04-12 | Novartis Ag | Un articulo que comprende un sustrato con un recubrimiento polimerico primario que porta grupos reactivos predominantemente en su superficie, unmetodo para preparar dicho articulo, un articulo que posee un recubrimiento de tipo hibrido y una lente de contacto |
US6107365A (en) * | 1997-09-03 | 2000-08-22 | The Regents Of The University Of California | Biomimetic hydrogel materials |
JP4111546B2 (ja) * | 1997-12-15 | 2008-07-02 | ウルトラデント プロダクツ インコーポレイテッド | 重合可能な隔離バリア、およびかかるバリアを形成しかつ使用する方法 |
CA2359318C (en) * | 1999-02-01 | 2009-06-30 | Donald Elbert | Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups |
US6379952B1 (en) | 1999-02-01 | 2002-04-30 | 3M Innovative Properties Company | Method for cell selection utilizing azlactone-functional supports |
US6958212B1 (en) * | 1999-02-01 | 2005-10-25 | Eidgenossische Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
WO2000052516A2 (en) | 1999-03-01 | 2000-09-08 | Boston Innovative Optics, Inc. | System and method for increasing the depth of focus of the human eye |
US6630243B2 (en) * | 1999-05-20 | 2003-10-07 | Bausch & Lomb Incorporated | Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating |
US6440571B1 (en) * | 1999-05-20 | 2002-08-27 | Bausch & Lomb Incorporated | Surface treatment of silicone medical devices with reactive hydrophilic polymers |
AUPQ197799A0 (en) | 1999-08-02 | 1999-08-26 | Commonwealth Scientific And Industrial Research Organisation | Hydrophilic biomedical compositions |
GB0002626D0 (en) | 2000-02-05 | 2000-03-29 | Eastman Kodak Co | Nonionic oligomeric surfactants and their use as dispersants and stabilisers |
US7291673B2 (en) * | 2000-06-02 | 2007-11-06 | Eidgenossiche Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
US6787635B2 (en) * | 2001-04-05 | 2004-09-07 | 3M Innovative Properties Company | Solid phase synthesis supports and methods |
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US8282912B2 (en) * | 2002-03-22 | 2012-10-09 | Kuros Biosurgery, AG | Compositions for tissue augmentation |
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CN1318463C (zh) * | 2003-09-24 | 2007-05-30 | 天津工业大学 | 一种环境响应型共聚水凝胶及其制备方法 |
US20050228484A1 (en) * | 2004-03-11 | 2005-10-13 | Trivascular, Inc. | Modular endovascular graft |
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IE56908B1 (en) * | 1983-09-08 | 1992-01-29 | Minnesota Mining & Mfg | Polymer blends with high water absorption |
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DE3521684A1 (de) * | 1985-06-18 | 1986-12-18 | Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg | Verfahren zur beschichtung von polymeren |
JPH0796023B2 (ja) * | 1985-08-23 | 1995-10-18 | ワシントン リサ−チ フアンデイシヨン | 表面の性質が改良された高分子眼内レンズ |
JPS6283885A (ja) * | 1985-10-08 | 1987-04-17 | Nitto Electric Ind Co Ltd | 酵素固定膜及びその製造方法 |
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US4772283A (en) * | 1986-05-16 | 1988-09-20 | White Thomas C | Corneal implant |
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CA2001720C (en) * | 1988-10-31 | 2001-10-02 | Randal A. Goffe | Membrane affinity apparatus and purification methods related thereto |
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US5081197A (en) * | 1990-10-23 | 1992-01-14 | Minnesota Mining And Manufacturing Company | Oligo(2-alkenyl azlactones) |
EP0555329B1 (de) * | 1990-10-30 | 1996-06-12 | Minnesota Mining And Manufacturing Company | Gegenstände mit einer hydrophilen polymeren schale und verfahren zu deren herstellung |
US5200471A (en) * | 1990-11-05 | 1993-04-06 | Minnesota Mining And Manufacturing Company | Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same |
-
1992
- 1992-06-24 US US07/903,367 patent/US5292514A/en not_active Expired - Lifetime
-
1993
- 1993-05-13 CA CA002136728A patent/CA2136728A1/en not_active Abandoned
- 1993-05-13 DE DE69316751T patent/DE69316751T2/de not_active Expired - Fee Related
- 1993-05-13 EP EP93913870A patent/EP0647143B1/de not_active Expired - Lifetime
- 1993-05-13 JP JP6502338A patent/JPH07508196A/ja active Pending
- 1993-05-13 WO PCT/US1993/004554 patent/WO1994000165A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0647143A1 (de) | 1995-04-12 |
EP0647143B1 (de) | 1998-01-28 |
JPH07508196A (ja) | 1995-09-14 |
US5292514A (en) | 1994-03-08 |
CA2136728A1 (en) | 1994-01-06 |
WO1994000165A2 (en) | 1994-01-06 |
DE69316751D1 (de) | 1998-03-05 |
WO1994000165A3 (en) | 1994-02-17 |
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