DE69304092D1 - Knochenersatzwerkstoff und Verfahren zu seiner Herstellung - Google Patents

Knochenersatzwerkstoff und Verfahren zu seiner Herstellung

Info

Publication number
DE69304092D1
DE69304092D1 DE69304092T DE69304092T DE69304092D1 DE 69304092 D1 DE69304092 D1 DE 69304092D1 DE 69304092 T DE69304092 T DE 69304092T DE 69304092 T DE69304092 T DE 69304092T DE 69304092 D1 DE69304092 D1 DE 69304092D1
Authority
DE
Germany
Prior art keywords
sheet
mixture
animal
bone
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69304092T
Other languages
English (en)
Other versions
DE69304092T2 (de
Inventor
Michio Ito
Hiroshi Yagasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MATSUMOTO DENTAL COLLEGE SHIOJ
Original Assignee
MATSUMOTO DENTAL COLLEGE SHIOJ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02410692A external-priority patent/JP3208585B2/ja
Priority claimed from JP02411192A external-priority patent/JP3208586B2/ja
Application filed by MATSUMOTO DENTAL COLLEGE SHIOJ filed Critical MATSUMOTO DENTAL COLLEGE SHIOJ
Application granted granted Critical
Publication of DE69304092D1 publication Critical patent/DE69304092D1/de
Publication of DE69304092T2 publication Critical patent/DE69304092T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/876—Calcium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
DE69304092T 1992-02-10 1993-02-09 Knochenersatzwerkstoff und Verfahren zu seiner Herstellung Expired - Fee Related DE69304092T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP02410692A JP3208585B2 (ja) 1992-02-10 1992-02-10 硬化型中性骨形成物の製造方法
JP02411192A JP3208586B2 (ja) 1992-02-10 1992-02-10 シート状骨補填剤の製造方法

Publications (2)

Publication Number Publication Date
DE69304092D1 true DE69304092D1 (de) 1996-09-26
DE69304092T2 DE69304092T2 (de) 1997-01-02

Family

ID=26361594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69304092T Expired - Fee Related DE69304092T2 (de) 1992-02-10 1993-02-09 Knochenersatzwerkstoff und Verfahren zu seiner Herstellung

Country Status (4)

Country Link
US (1) US6214048B1 (de)
EP (1) EP0555807B1 (de)
AT (1) ATE141493T1 (de)
DE (1) DE69304092T2 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5507813A (en) * 1993-12-09 1996-04-16 Osteotech, Inc. Shaped materials derived from elongate bone particles
IT1295308B1 (it) * 1997-10-10 1999-05-04 Gentili Ist Spa Complessi amorfi di chitosani e sali insolubili di metalli alcalino terrosi e loro uso come medicamenti utili nella osteogenesi
JP3143660B2 (ja) * 1997-11-27 2001-03-07 工業技術院長 亜鉛含有リン酸三カルシウムからなるセラミックス及び亜鉛徐放性生体用セラミックス
US6030635A (en) * 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
KR100563476B1 (ko) * 1998-07-03 2006-03-27 이진용 골재생재료
EP1123081B1 (de) * 1998-10-19 2002-12-11 SYNTHES AG Chur Aushärtbarer keramischer hydraulischer zement
US7168952B2 (en) * 1999-05-12 2007-01-30 Pentron Clinical Technologies, Llc Endodontic post and obturating system
US7086864B2 (en) * 1999-05-12 2006-08-08 Pentron Clinical Technologies, Llc Endodontic post system
US7163401B2 (en) * 1999-05-12 2007-01-16 Pentron Clinical Technologies, Llc Endodontic post and obturating system
JP4472804B2 (ja) * 1999-05-18 2010-06-02 学校法人松本歯科大学 骨補填剤及びその製造方法
AU782394B2 (en) 1999-06-29 2005-07-21 J. Alexander Marchosky Compositions and methods for forming and strengthening bone
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
US9387094B2 (en) 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
ES2169681B1 (es) * 2000-08-10 2003-10-01 Osfarma S L Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
US7323193B2 (en) 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
EP1416874A4 (de) * 2001-07-16 2007-04-18 Depuy Products Inc Biologische/synthetische poröse extrazelluläre hybrid-matrixgerüste
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
AU2002354913B2 (en) * 2001-07-16 2008-07-17 Depuy Products, Inc. Unitary surgical device and method
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
AU2002354911B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Meniscus regeneration device and method
AU2002322567B2 (en) * 2001-07-16 2007-09-06 Depuy Products, Inc. Devices form naturally occurring biologically derived
WO2003007787A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Cartilage repair and regeneration device and method
KR20040047746A (ko) 2001-10-12 2004-06-05 오스테오테크, 인코포레이티드 향상된 골 이식물
US7204874B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Root canal filling material
US7211136B2 (en) * 2001-10-24 2007-05-01 Pentron Clinical Technologies, Llc Dental filling material
US7204875B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Dental filling material
US7303817B2 (en) * 2001-10-24 2007-12-04 Weitao Jia Dental filling material
JP2003128704A (ja) 2001-10-24 2003-05-08 Matsumoto Shika Univ キチン・キトサンの低分子化方法及び骨伝導物の製造方法
US7750063B2 (en) 2001-10-24 2010-07-06 Pentron Clinical Technologies, Llc Dental filling material
AU2002362220A1 (en) 2001-12-27 2003-07-24 Osteotech Inc. Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners
JP2007503292A (ja) 2003-06-11 2007-02-22 オステオテック インコーポレーテッド 骨インプラント及びその製造方法
CA2535244A1 (en) * 2003-08-08 2005-02-17 Dentsply International Inc. Method and product for phosphosilicate slurry for use in dentistry and related bone cements
JP2005087440A (ja) * 2003-09-17 2005-04-07 Matsumoto Shika Univ 海洋生物の原料を含む組成物、及びその組成物の製造方法
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
WO2007060024A2 (de) 2005-11-25 2007-05-31 Markus Lietzau Verwendung von knochenkleber zum apikalen abdichten eines zahnwurzelkanals
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
EP2358352B1 (de) 2008-10-24 2018-08-29 Warsaw Orthopedic, Inc. Zusammensetzungen und verfahren zur förderung von knochenbildung
US20100268341A1 (en) * 2009-04-16 2010-10-21 WARSAW ORTHOPEDIC, INC., An Indian Corporation Minimally invasive expandable vertebral implant and method
CO6530149A1 (es) * 2011-03-28 2012-09-28 Sur Occidental De Aceites Biocompuesto ceramico para regeneracion osea
US9040093B2 (en) * 2013-03-13 2015-05-26 Orthovita, Inc. Bone graft materials containing calcium phosphate and chitosan
CN103656753B (zh) * 2013-12-04 2015-04-22 上海纳米技术及应用国家工程研究中心有限公司 磷酸钙系中性骨水泥及其制备方法
CN110869065B (zh) 2017-04-13 2022-07-01 塞普托东专业股份有限公司 包含硅酸钙的结缔组织例如骨、牙本质或牙髓再生材料
EP3388092A1 (de) 2017-04-13 2018-10-17 Septodont ou Septodont SAS ou Specialites Septodont Bindegewebe, wie knochen, dentin oder zellstoff, regeneratives material mit kalziumsilikat
CN112220964A (zh) * 2020-10-19 2021-01-15 西安点云生物科技有限公司 一种复合生物陶瓷粉及其制备的复合生物陶瓷人工骨和制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2101036A1 (en) * 1970-08-12 1972-03-31 Meyer Jean Dentine treatment - using compsn contg trioxymethylene
JPS585861B2 (ja) 1975-08-13 1983-02-02 ミサワホ−ム株式会社 キカイテキキヨウドノ スグレタスイコウセイムキブツシツノ セイゾウホウホウ
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
US4772591A (en) 1985-09-25 1988-09-20 Peritain, Ltd. Method for accelerated wound healing
US5180426A (en) * 1987-12-28 1993-01-19 Asahi Kogaku Kogyo K.K. Composition for forming calcium phosphate type setting material and process for producing setting material
JPH0735281B2 (ja) * 1988-02-16 1995-04-19 学校法人松本歯科大学 硬化性組成物
GB8813033D0 (en) * 1988-06-02 1988-07-06 Geistlich Soehne Ag Chemical compound
DE68915265T2 (de) * 1988-08-10 1995-01-05 Nitta Gelatin Kk Ärztliches und zahnärztliches vernetzbares material.
JPH02241460A (ja) 1989-03-16 1990-09-26 Asahi Optical Co Ltd 骨修復用複合材料
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair

Also Published As

Publication number Publication date
DE69304092T2 (de) 1997-01-02
ATE141493T1 (de) 1996-09-15
EP0555807B1 (de) 1996-08-21
EP0555807A1 (de) 1993-08-18
US6214048B1 (en) 2001-04-10

Similar Documents

Publication Publication Date Title
DE69304092T2 (de) Knochenersatzwerkstoff und Verfahren zu seiner Herstellung
FR2776282B1 (fr) Procede de preparation d'un biomateriau a base d'hydroxyapatite, biomateriau obtenu et application chirurgicale ou dentaire
ATE279950T1 (de) Zusammensetzung zur implantation in den menschlichen und tierischen körper
ATE74751T1 (de) Oestradiol-implantat und verfahren zu seiner herstellung.
ATE88322T1 (de) Bakterienhemmende zusammensetzungen und deren verwendung.
AU551364B2 (en) Process and composition for conditioning an aqueous system
CA2147766A1 (en) Process for treating a metallic surgical implant
HUT65415A (en) Fluoralkenyl compounds, their use as pest repellents and pesticides, pesticides containing the compounds as active ingredients, and process for producing the compounds
IL72364A0 (en) Controlled release compositions of biologically active materials and their preparation
ZA952771B (en) Novel compound
JPS6437445A (en) Calcium phosphate hydraulic cement composition
HU911993D0 (en) Process for the covering of active agents with ph-sensitive polymers
IL67286A (en) Urea derivatives,their manufacture and their use as herbicides
HU905721D0 (en) Pesticide compositions and process for producing substituted acrylic acid esthers used as active components in them
EP0363040A3 (de) Unkrautbekämpfungsmittel
DE3267766D1 (en) N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth
HUT46842A (en) Biocompatible layered body containing calcium phosphate and method for producing same
GR3000202T3 (en) Cyclohexenone derivatives, process for their preparation and their use as herbicides and plant growth regulating agents
DE3377578D1 (en) Antimicrobial disulfide prodrugs
IE820199L (en) Dibenzofuran derivatives
IL64430A (en) Trifluoromethoxyphenyl-(di)-thiophosphoric acid esters,their manufacture and their use as pesticides
HUT48580A (en) Process for production of t-/1h-pirrol-3-il/ substituated 3,5-dihydroxi-hept-6-en acids and 3,5-dihydroxi heptane acids and medical preparatives containing them as active substance
DE3269673D1 (en) Thiazolo (2,3-b)-quinazolones and process for their preparation
DE2961632D1 (en) Stabilised granular nematocidal and insecticidal composition having o-ethyl-s,s-dipropyl dithiophosphate as an active substance, and method of preparing it
JPS57170165A (en) Active calcium fortifier

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee