DE69228262D1 - Verfahren zum Herstellen von Lignin-Analoga und Ausgangsprodukte dafür - Google Patents
Verfahren zum Herstellen von Lignin-Analoga und Ausgangsprodukte dafürInfo
- Publication number
- DE69228262D1 DE69228262D1 DE69228262T DE69228262T DE69228262D1 DE 69228262 D1 DE69228262 D1 DE 69228262D1 DE 69228262 T DE69228262 T DE 69228262T DE 69228262 T DE69228262 T DE 69228262T DE 69228262 D1 DE69228262 D1 DE 69228262D1
- Authority
- DE
- Germany
- Prior art keywords
- lower alkyl
- chem
- formula
- ring
- lignin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/22—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one naphthalene or hydrogenated naphthalene ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29811991 | 1991-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69228262D1 true DE69228262D1 (de) | 1999-03-04 |
Family
ID=17855421
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69211994T Expired - Fee Related DE69211994T2 (de) | 1991-10-17 | 1992-10-15 | Lignan-analoge, ihre herstellung und hypolipidemische arzneimittel |
DE69228262T Expired - Fee Related DE69228262D1 (de) | 1991-10-17 | 1992-10-15 | Verfahren zum Herstellen von Lignin-Analoga und Ausgangsprodukte dafür |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69211994T Expired - Fee Related DE69211994T2 (de) | 1991-10-17 | 1992-10-15 | Lignan-analoge, ihre herstellung und hypolipidemische arzneimittel |
Country Status (12)
Country | Link |
---|---|
US (4) | US5420333A (de) |
EP (2) | EP0597107B1 (de) |
JP (1) | JP2839805B2 (de) |
KR (1) | KR100252428B1 (de) |
AT (2) | ATE139990T1 (de) |
DE (2) | DE69211994T2 (de) |
DK (2) | DK0597107T3 (de) |
ES (2) | ES2091488T3 (de) |
GR (1) | GR3020461T3 (de) |
HU (1) | HU211296A9 (de) |
TW (1) | TW209215B (de) |
WO (1) | WO1993008155A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1046937C (zh) * | 1993-04-16 | 1999-12-01 | 盐野义制药株式会社 | 木酚素系化合物的制备方法 |
FR2707980B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux cyclohept[b]indoles et cyclooct[b]indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
AU2353095A (en) * | 1994-06-22 | 1996-01-15 | Shionogi & Co., Ltd. | Process for producing phthalide compound |
ID18046A (id) * | 1996-08-20 | 1998-02-19 | Takeda Chemical Industries Ltd | Senyawa siklik campuran, pembuatan dan penngunaannya. |
EP1135119A4 (de) * | 1998-11-12 | 2004-11-03 | Alteon Inc | Glukose- und lipidsenkende verbindungen |
KR100352269B1 (ko) * | 1999-10-08 | 2002-09-12 | 한국생명공학연구원 | 저밀도 지질 단백질에 대해 항산화 활성을 갖는 리그난계 화합물 |
FR2800738B1 (fr) | 1999-11-04 | 2002-02-08 | Corning Sa | Naphtopyranes ayant un substituant perfluoroalkyle en position 5, preparation et compositions et matrices (co)polymeres les renfermant |
US6770024B1 (en) | 2000-03-28 | 2004-08-03 | Stony Brook Surgical Innovations, Inc. | Implantable counterpulsation cardiac assist device |
TWI241195B (en) * | 2000-04-10 | 2005-10-11 | Shionogi & Co | Preventive agent for bile acidic diarrhea |
WO2002009757A1 (fr) * | 2000-08-01 | 2002-02-07 | Shionogi & Co., Ltd. | Agents de prevention ou remedes contre l'obesite ou la steatose hepatique |
WO2004033411A1 (ja) * | 2002-10-08 | 2004-04-22 | Shionogi & Co., Ltd. | エノンエステルの製造法 |
US7152611B2 (en) * | 2002-12-30 | 2006-12-26 | International Tape Partners, Llc | Coated multifilament dental devices overcoated with imbedded particulate |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
ES2552657T3 (es) | 2010-05-26 | 2015-12-01 | Satiogen Pharmaceuticals, Inc. | Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias |
BR112014010223B8 (pt) | 2011-10-28 | 2021-02-23 | Lumena Pharmaceuticals Llc | uso de uma composição compreendendo inibidores de reciclagem de ácido de bílis e forma de dosagem pediátrica |
CN104023718B (zh) | 2011-10-28 | 2017-04-05 | 鲁美纳医药公司 | 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 |
KR20230152818A (ko) | 2013-03-15 | 2023-11-03 | 샤이어 휴먼 지네틱 테라피즈 인크. | 원발성 담관염 및 염증성 장 질환 치료용 담즙산 재순환 억제제 |
RU2015139732A (ru) | 2013-03-15 | 2017-04-24 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециркуляции желчных кислот для лечения пищевода барретта и гастроэзофагеальной рефлюксной болезни |
AU2020221239A1 (en) | 2019-02-12 | 2021-09-16 | Mirum Pharmaceuticals, Inc. | Methods for treating cholestasis |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO170760C (no) * | 1985-01-10 | 1992-12-02 | Tanabe Seiyaku Co | Analogifremgangsmaate for fremstilling av terapeutisk aktive nafthalenderivater |
JPS6310746A (ja) * | 1986-07-01 | 1988-01-18 | Tanabe Seiyaku Co Ltd | ナフタレン誘導体 |
JPH0372422A (ja) * | 1989-05-16 | 1991-03-27 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
-
1992
- 1992-10-15 KR KR1019930701814A patent/KR100252428B1/ko not_active IP Right Cessation
- 1992-10-15 WO PCT/JP1992/001342 patent/WO1993008155A1/ja active IP Right Grant
- 1992-10-15 ES ES92921331T patent/ES2091488T3/es not_active Expired - Lifetime
- 1992-10-15 DK DK92921331.2T patent/DK0597107T3/da active
- 1992-10-15 DE DE69211994T patent/DE69211994T2/de not_active Expired - Fee Related
- 1992-10-15 JP JP4277151A patent/JP2839805B2/ja not_active Expired - Fee Related
- 1992-10-15 DE DE69228262T patent/DE69228262D1/de not_active Expired - Fee Related
- 1992-10-15 EP EP92921331A patent/EP0597107B1/de not_active Expired - Lifetime
- 1992-10-15 EP EP95117572A patent/EP0701991B1/de not_active Expired - Lifetime
- 1992-10-15 DK DK95117572T patent/DK0701991T3/da active
- 1992-10-15 AT AT92921331T patent/ATE139990T1/de not_active IP Right Cessation
- 1992-10-15 US US08/078,205 patent/US5420333A/en not_active Expired - Lifetime
- 1992-10-15 ES ES95117572T patent/ES2129733T3/es not_active Expired - Lifetime
- 1992-10-15 AT AT95117572T patent/ATE175954T1/de not_active IP Right Cessation
- 1992-10-17 TW TW081108267A patent/TW209215B/zh active
-
1994
- 1994-09-07 US US08/301,996 patent/US5449814A/en not_active Expired - Lifetime
-
1995
- 1995-04-18 US US08/423,346 patent/US5731455A/en not_active Expired - Fee Related
- 1995-05-22 US US08/445,506 patent/US5502216A/en not_active Expired - Fee Related
- 1995-06-30 HU HU95P/P00635P patent/HU211296A9/hu unknown
-
1996
- 1996-07-04 GR GR960401618T patent/GR3020461T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0701991T3 (da) | 1999-09-13 |
TW209215B (de) | 1993-07-11 |
DE69211994D1 (de) | 1996-08-08 |
ATE139990T1 (de) | 1996-07-15 |
EP0701991B1 (de) | 1999-01-20 |
US5502216A (en) | 1996-03-26 |
JP2839805B2 (ja) | 1998-12-16 |
ATE175954T1 (de) | 1999-02-15 |
KR100252428B1 (ko) | 2000-04-15 |
KR930703236A (ko) | 1993-11-29 |
JPH05310634A (ja) | 1993-11-22 |
US5449814A (en) | 1995-09-12 |
EP0597107A4 (de) | 1994-02-03 |
DE69211994T2 (de) | 1997-02-20 |
EP0597107A1 (de) | 1994-05-18 |
HU211296A9 (en) | 1995-11-28 |
WO1993008155A1 (en) | 1993-04-29 |
DK0597107T3 (da) | 1996-07-29 |
GR3020461T3 (en) | 1996-10-31 |
EP0701991A1 (de) | 1996-03-20 |
ES2091488T3 (es) | 1996-11-01 |
EP0597107B1 (de) | 1996-07-03 |
ES2129733T3 (es) | 1999-06-16 |
US5731455A (en) | 1998-03-24 |
US5420333A (en) | 1995-05-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |