ATE92492T1 - Verfahren zur herstellung von 2-betasubstituierten-methyl-penicillinderivaten. - Google Patents

Verfahren zur herstellung von 2-betasubstituierten-methyl-penicillinderivaten.

Info

Publication number
ATE92492T1
ATE92492T1 AT89301925T AT89301925T ATE92492T1 AT E92492 T1 ATE92492 T1 AT E92492T1 AT 89301925 T AT89301925 T AT 89301925T AT 89301925 T AT89301925 T AT 89301925T AT E92492 T1 ATE92492 T1 AT E92492T1
Authority
AT
Austria
Prior art keywords
substituted
chem
beta
compound
preparation
Prior art date
Application number
AT89301925T
Other languages
English (en)
Inventor
Sigeru Torii
Hideo Tanaka
Motoaki Tanaka
Shozo Yamada
Akira Nakai
Original Assignee
Taiho Pharmaceutical Co Ltd
Otsuka Kagaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, Otsuka Kagaku Kk filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE92492T1 publication Critical patent/ATE92492T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • C07D499/06Preparation by forming the ring or condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
AT89301925T 1988-03-01 1989-02-27 Verfahren zur herstellung von 2-betasubstituierten-methyl-penicillinderivaten. ATE92492T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63049038A JP2599610B2 (ja) 1988-03-01 1988-03-01 2β―置換メチルペニシリン誘導体の製造法
EP89301925A EP0331394B1 (de) 1988-03-01 1989-02-27 Verfahren zur Herstellung von 2-beta-substituierten-Methyl-penicillinderivaten

Publications (1)

Publication Number Publication Date
ATE92492T1 true ATE92492T1 (de) 1993-08-15

Family

ID=12819915

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89301925T ATE92492T1 (de) 1988-03-01 1989-02-27 Verfahren zur herstellung von 2-betasubstituierten-methyl-penicillinderivaten.

Country Status (10)

Country Link
US (1) US4898939A (de)
EP (1) EP0331394B1 (de)
JP (1) JP2599610B2 (de)
KR (1) KR910001308B1 (de)
CN (1) CN1022836C (de)
AT (1) ATE92492T1 (de)
AU (1) AU600403B2 (de)
CA (1) CA1339124C (de)
DE (1) DE68907953T2 (de)
ES (1) ES2058499T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6897780B2 (en) * 1993-07-12 2005-05-24 Hill-Rom Services, Inc. Bed status information system for hospital beds
TW200523264A (en) * 2003-10-09 2005-07-16 Otsuka Chemical Co Ltd CMPB crystal and method for producing the same
TW200519119A (en) * 2003-10-10 2005-06-16 Otsuka Chemical Co Ltd PENAM crystal and process for producing the same
CN107033161B (zh) * 2017-05-04 2019-01-01 石家庄万业化工科技有限公司 一种他唑巴坦酸的合成方法
WO2021120063A1 (zh) * 2019-12-18 2021-06-24 凯莱英医药集团(天津)股份有限公司 他唑巴坦中间体的连续合成方法
CN114031629A (zh) * 2021-12-10 2022-02-11 山东安舜制药有限公司 一种合成他唑巴坦中间体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
JPS58225091A (ja) * 1982-06-21 1983-12-27 Taiho Yakuhin Kogyo Kk ペニシリン誘導体及びその製造法
US4464237A (en) * 1982-08-09 1984-08-07 Otsuka Kagaku Yakuhin Kabushiki Kaisha Process for preparing β-lactam derivatives
US4562073A (en) * 1982-12-24 1985-12-31 Taiho Pharmaceutical Company Limited Penicillin derivatives
US4496484A (en) * 1983-04-22 1985-01-29 Taiho Pharmaceutical Company, Limited Penicillin derivatives
CA1239392A (en) * 1983-10-13 1988-07-19 Shigeru Yamabe Penicillin derivatives and process for preparing the same
GB2157286B (en) * 1984-04-12 1987-12-31 Leo Pharm Prod Ltd B-lactam antibiotic potentiators
JPS62294686A (ja) * 1987-05-29 1987-12-22 Taiho Yakuhin Kogyo Kk ペニシラン酸誘導体

Also Published As

Publication number Publication date
JPH01224377A (ja) 1989-09-07
CN1036767A (zh) 1989-11-01
AU3029089A (en) 1989-09-07
DE68907953T2 (de) 1993-11-18
AU600403B2 (en) 1990-08-09
CA1339124C (en) 1997-07-29
JP2599610B2 (ja) 1997-04-09
CN1022836C (zh) 1993-11-24
US4898939A (en) 1990-02-06
EP0331394B1 (de) 1993-08-04
DE68907953D1 (de) 1993-09-09
EP0331394A1 (de) 1989-09-06
KR910001308B1 (ko) 1991-03-02
ES2058499T3 (es) 1994-11-01
KR890014554A (ko) 1989-10-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time