DE69225960D1 - Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen - Google Patents

Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen

Info

Publication number
DE69225960D1
DE69225960D1 DE69225960T DE69225960T DE69225960D1 DE 69225960 D1 DE69225960 D1 DE 69225960D1 DE 69225960 T DE69225960 T DE 69225960T DE 69225960 T DE69225960 T DE 69225960T DE 69225960 D1 DE69225960 D1 DE 69225960D1
Authority
DE
Germany
Prior art keywords
monoclonal antibodies
methods
antibodies against
against possible
hcv envelope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69225960T
Other languages
English (en)
Other versions
DE69225960T2 (de
Inventor
Mary Gibadlo
Joan Tyner
Larry Mimms
David Vallari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69225960D1 publication Critical patent/DE69225960D1/de
Publication of DE69225960T2 publication Critical patent/DE69225960T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69225960T 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen Expired - Lifetime DE69225960T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64847591A 1991-01-31 1991-01-31
PCT/US1992/000687 WO1992013892A1 (en) 1991-01-31 1992-01-30 Monoclonal antibodies to putative hcv envelope region and methods for using same

Publications (2)

Publication Number Publication Date
DE69225960D1 true DE69225960D1 (de) 1998-07-23
DE69225960T2 DE69225960T2 (de) 1999-01-21

Family

ID=24600936

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69225960T Expired - Lifetime DE69225960T2 (de) 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen

Country Status (11)

Country Link
EP (1) EP0569537B1 (de)
JP (1) JP3483555B2 (de)
KR (1) KR930703361A (de)
AT (1) ATE167522T1 (de)
AU (1) AU662517B2 (de)
CA (1) CA2101534C (de)
DE (1) DE69225960T2 (de)
DK (1) DK0569537T3 (de)
ES (1) ES2118129T3 (de)
HK (1) HK1012838A1 (de)
WO (1) WO1992013892A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227547B1 (en) 1991-06-24 2011-08-29 Novartis Vaccines & Diagnostic Hepatitis c virus (hcv) polypeptides
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
ES2174957T5 (es) * 1994-07-29 2006-12-16 Innogenetics N.V. Proteinas purificadas de envoltura de virus de la hepatitis c para uso diagnostico y terapeutico.
EP0947525A1 (de) * 1998-03-27 1999-10-06 Innogenetics N.V. Epitope in der viralen Hüllproteine und spezifische Antikörper gegen diese Epitope: Verwendung für die detektion von viralantigene im empfängergewebe
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
ATE352785T1 (de) * 1999-07-28 2007-02-15 Novartis Vaccines & Diagnostic Verfahren zum nachweis von hepatitis c antigenen
KR101518081B1 (ko) 2007-02-21 2015-05-06 유니버시티 오브 매사추세츠 Ｃ형 간염 바이러스(ｈｃｖ)에 대한 인간 항체 및 이것의 용도
CA2694397A1 (en) 2007-07-25 2009-01-29 Japan As Represented By Director-General Of National Institute Of Infect Ious Diseases Antibody having inhibitory activity on infection with hepatitis c virus (hcv) and use thereof
WO2010038789A1 (ja) 2008-09-30 2010-04-08 東レ株式会社 Ｃ型肝炎ウイルスのエンベロープタンパク質２に結合する抗体及びそれを用いたｃ型肝炎ウイルスの遺伝子型の同定方法
EP2495256A4 (de) 2009-10-30 2013-09-25 Toray Industries Antikörper mit hemmender wirkung auf infektionen mit hepatitis-c-virus (hcv) und seine verwendung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982002774A1 (en) * 1981-02-11 1982-08-19 Baxter Travenol Lab Non-a,non-b hepatitis virus
IE62868B1 (en) * 1987-11-18 1995-03-08 Chiron Corp Hepatitis C virus
UA50829C2 (uk) * 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
EP0527786A1 (de) * 1990-04-03 1993-02-24 Southwest Foundation For Biomedical Research Gereinigtes hcv und proteine und peptide von hcv
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DE59109221D1 (de) * 1990-11-03 2001-11-15 Dade Behring Marburg Gmbh HCV-spezifische Peptide, Mittel dazu und ihre Verwendung
DE69131046T2 (de) * 1990-11-07 1999-10-21 Abbott Lab Monoklonale antikörper gegen den hepatitis c-virus und verfahren diese zu benutzen

Also Published As

Publication number Publication date
CA2101534C (en) 2004-01-20
EP0569537B1 (de) 1998-06-17
AU662517B2 (en) 1995-09-07
WO1992013892A1 (en) 1992-08-20
DK0569537T3 (da) 1999-04-06
EP0569537A1 (de) 1993-11-18
EP0569537A4 (en) 1994-10-05
KR930703361A (ko) 1993-11-29
ATE167522T1 (de) 1998-07-15
JP3483555B2 (ja) 2004-01-06
DE69225960T2 (de) 1999-01-21
JPH06505389A (ja) 1994-06-23
CA2101534A1 (en) 1992-08-01
HK1012838A1 (en) 1999-08-06
AU1362792A (en) 1992-09-07
ES2118129T3 (es) 1998-09-16

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