ES2118129T3 - Anticuerpos monoclonales contra las regiones de cubierta putativas del virus vhc y procedimientos de utilizacion de estos. - Google Patents

Anticuerpos monoclonales contra las regiones de cubierta putativas del virus vhc y procedimientos de utilizacion de estos.

Info

Publication number
ES2118129T3
ES2118129T3 ES92906219T ES92906219T ES2118129T3 ES 2118129 T3 ES2118129 T3 ES 2118129T3 ES 92906219 T ES92906219 T ES 92906219T ES 92906219 T ES92906219 T ES 92906219T ES 2118129 T3 ES2118129 T3 ES 2118129T3
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
putative
procedures
antibodies against
cover regions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92906219T
Other languages
English (en)
Inventor
Mary S Gibadlo
Joan D Tyner
Larry T Mimms
David S Vallari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2118129T3 publication Critical patent/ES2118129T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

ANTICUERPOS MONOCLONALES QUE SE UNEN ESPECIFICAMENTE A LA REGION ENVOLVENTE DEL VIRUS DE LA HEPATITIS C PUTATIVO (HCV). TAMBIEN SE PRESENTAN LAS LINEAS CELULARES DE HIBRIDOMAS QUE SEGREGAN ESTOS ANTICUERPOS MONOCLONALES, LOS METODOS PARA LA UTILIZACION DE ESTOS ANTICUERPOS MONOCLONALES Y LOS KITS DE ENSAYO QUE CONTIENEN ESTOS ANTICUERPOS MONOCLONALES.
ES92906219T 1991-01-31 1992-01-30 Anticuerpos monoclonales contra las regiones de cubierta putativas del virus vhc y procedimientos de utilizacion de estos. Expired - Lifetime ES2118129T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64847591A 1991-01-31 1991-01-31

Publications (1)

Publication Number Publication Date
ES2118129T3 true ES2118129T3 (es) 1998-09-16

Family

ID=24600936

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92906219T Expired - Lifetime ES2118129T3 (es) 1991-01-31 1992-01-30 Anticuerpos monoclonales contra las regiones de cubierta putativas del virus vhc y procedimientos de utilizacion de estos.

Country Status (11)

Country Link
EP (1) EP0569537B1 (es)
JP (1) JP3483555B2 (es)
KR (1) KR930703361A (es)
AT (1) ATE167522T1 (es)
AU (1) AU662517B2 (es)
CA (1) CA2101534C (es)
DE (1) DE69225960T2 (es)
DK (1) DK0569537T3 (es)
ES (1) ES2118129T3 (es)
HK (1) HK1012838A1 (es)
WO (1) WO1992013892A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2188583T3 (es) * 1991-06-24 2003-07-01 Chiron Corp Polipeptidos para el virus de la hepatitis c (hcv).
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
BR9506059A (pt) * 1994-07-29 1997-10-28 Innogenetics Nv Proteinas envelopes purificadas de virus c para uso de diagnóstico e terapêutico
EP0947525A1 (en) * 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
EP1295126B1 (en) * 1999-07-28 2007-01-24 Novartis Vaccines and Diagnostics, Inc. Hepatitis c viral antigen immunoassay detection systems
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
MX2009008706A (es) 2007-02-21 2009-09-14 Univ Massachusetts Anticuerpos humanos contra el virus de la hepatitis c (hcv) y usos de los mismos.
EP2177535A4 (en) 2007-07-25 2010-08-25 Jp Nat Inst Infectious Disease ANTIBODIES WITH HEMMETAL EFFECT ON INFECTIONS WITH HEPATITIS C VIRUS (HCV) AND ITS USE
DK2862876T3 (en) 2008-09-30 2016-05-23 Toray Industries Antibody binding to envelope protein 2 of hepatitis C virus and method for identifying the genotype of hepatitis C virus using the same
US8592559B2 (en) 2009-10-30 2013-11-26 Toray Industries, Inc. Antibody having activity of inhibiting hepatitis C virus (HCV) infection and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982002774A1 (en) * 1981-02-11 1982-08-19 Baxter Travenol Lab Non-a,non-b hepatitis virus
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
AU7672991A (en) * 1990-04-03 1991-10-30 Southwest Foundation For Biomedical Research Purified hcv and hcv proteins and peptides
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DE59109221D1 (de) * 1990-11-03 2001-11-15 Dade Behring Marburg Gmbh HCV-spezifische Peptide, Mittel dazu und ihre Verwendung
CA2095735C (en) * 1990-11-07 2004-02-03 Smriti U. Mehta Monoclonal antibodies to hepatitis c virus and method for using same

Also Published As

Publication number Publication date
EP0569537B1 (en) 1998-06-17
CA2101534A1 (en) 1992-08-01
EP0569537A1 (en) 1993-11-18
ATE167522T1 (de) 1998-07-15
DK0569537T3 (da) 1999-04-06
DE69225960D1 (de) 1998-07-23
EP0569537A4 (en) 1994-10-05
WO1992013892A1 (en) 1992-08-20
JPH06505389A (ja) 1994-06-23
KR930703361A (ko) 1993-11-29
HK1012838A1 (en) 1999-08-06
CA2101534C (en) 2004-01-20
DE69225960T2 (de) 1999-01-21
JP3483555B2 (ja) 2004-01-06
AU662517B2 (en) 1995-09-07
AU1362792A (en) 1992-09-07

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