DE69218471T2 - Verfahren zur Herstellung von biologisch aktiven Reagentien aus Succinimid enthaltenden Polymeren, analytisches Element und Verwendungsmethoden - Google Patents

Verfahren zur Herstellung von biologisch aktiven Reagentien aus Succinimid enthaltenden Polymeren, analytisches Element und Verwendungsmethoden

Info

Publication number
DE69218471T2
DE69218471T2 DE69218471T DE69218471T DE69218471T2 DE 69218471 T2 DE69218471 T2 DE 69218471T2 DE 69218471 T DE69218471 T DE 69218471T DE 69218471 T DE69218471 T DE 69218471T DE 69218471 T2 DE69218471 T2 DE 69218471T2
Authority
DE
Germany
Prior art keywords
biologically active
methods
reagents
preparation
polymers containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69218471T
Other languages
English (en)
Other versions
DE69218471D1 (de
Inventor
Richard Calvin Sutton
Ignazio Salvatore Ponticello
Susan Jean Danielson
Marsha Denise Bale Oenick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Johnson and Johnson Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Clinical Diagnostics Inc filed Critical Johnson and Johnson Clinical Diagnostics Inc
Application granted granted Critical
Publication of DE69218471D1 publication Critical patent/DE69218471D1/de
Publication of DE69218471T2 publication Critical patent/DE69218471T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S524/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S524/90—Antigen-antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69218471T 1991-01-25 1992-01-21 Verfahren zur Herstellung von biologisch aktiven Reagentien aus Succinimid enthaltenden Polymeren, analytisches Element und Verwendungsmethoden Expired - Lifetime DE69218471T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/646,303 US5308749A (en) 1991-01-25 1991-01-25 Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use

Publications (2)

Publication Number Publication Date
DE69218471D1 DE69218471D1 (de) 1997-04-30
DE69218471T2 true DE69218471T2 (de) 1997-07-03

Family

ID=24592533

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69218471T Expired - Lifetime DE69218471T2 (de) 1991-01-25 1992-01-21 Verfahren zur Herstellung von biologisch aktiven Reagentien aus Succinimid enthaltenden Polymeren, analytisches Element und Verwendungsmethoden

Country Status (11)

Country Link
US (1) US5308749A (de)
EP (1) EP0496473B1 (de)
JP (1) JP3110839B2 (de)
KR (1) KR100209072B1 (de)
AT (1) ATE150871T1 (de)
CA (1) CA2058515C (de)
DE (1) DE69218471T2 (de)
FI (1) FI102921B (de)
HK (1) HK115297A (de)
IE (2) IE920215A1 (de)
TW (1) TW218037B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2290364A1 (de) 1996-04-25 2011-03-02 BioArray Solutions Ltd. Lichtgesteuerte elektrokinetische Anordnung von Partikeln in der Nähe von Oberflächen
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6107357A (en) * 1999-11-16 2000-08-22 International Business Machines Corporatrion Dielectric compositions and method for their manufacture
US6342454B1 (en) * 1999-11-16 2002-01-29 International Business Machines Corporation Electronic devices with dielectric compositions and method for their manufacture
AU7299301A (en) 2000-06-21 2002-01-02 Bioarray Solutions Ltd Multianalyte molecular analysis using application-specific random particle arrays
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US20020019004A1 (en) * 2000-08-03 2002-02-14 Albert Orfao Method for isolating molecules, cells and other particles which are specifically bound to a large particle
US6685983B2 (en) 2001-03-14 2004-02-03 International Business Machines Corporation Defect-free dielectric coatings and preparation thereof using polymeric nitrogenous porogens
US6670285B2 (en) 2001-03-14 2003-12-30 International Business Machines Corporation Nitrogen-containing polymers as porogens in the preparation of highly porous, low dielectric constant materials
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
EP2722395B1 (de) 2001-10-15 2018-12-19 Bioarray Solutions Ltd Gemultiplexte Analyse polymorphischer Stellen durch gleichzeitige Abfrage und enzymvermittelte Detektion
JP2004075823A (ja) * 2002-08-15 2004-03-11 Fuji Xerox Co Ltd 非架橋重合体粒子の製造方法
JP4178872B2 (ja) * 2002-08-15 2008-11-12 富士ゼロックス株式会社 架橋重合体粒子の製造方法
JP4218281B2 (ja) * 2002-08-21 2009-02-04 富士ゼロックス株式会社 機能性重合体粒子の製造方法
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
WO2004104172A2 (en) * 2003-05-15 2004-12-02 Bioarray Solutions, Ltd. Hybridization-mediated analysis of polymorphisms
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
WO2005031305A2 (en) 2003-09-22 2005-04-07 Bioarray Solutions, Ltd. Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
JP2007521017A (ja) 2003-10-28 2007-08-02 バイオアレイ ソリューションズ リミテッド 固定化捕捉プローブを用いる遺伝子発現分析法の最適化
AU2004287069B2 (en) 2003-10-29 2009-07-16 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US6969579B1 (en) * 2004-12-21 2005-11-29 Eastman Kodak Company Solvent resistant imageable element
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
JP2007041935A (ja) 2005-08-04 2007-02-15 Hosiden Corp メモリカード用アダプタ
JP2014102194A (ja) * 2012-11-21 2014-06-05 Sumitomo Bakelite Co Ltd 高分子物質、および高分子物質で表面が被覆された担体

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264766A (en) * 1877-09-19 1981-04-28 Hoffmann-La Roche Inc. Immunological diagnostic reagents
US3857931A (en) * 1971-02-01 1974-12-31 Hoffmann La Roche Latex polymer reagents for diagnostic tests
CH601364A5 (en) * 1975-06-18 1978-07-14 Ciba Geigy Ag Polymers crosslinkable by electromagnetic radiation
US4138383A (en) * 1975-11-24 1979-02-06 California Institute Of Technology Preparation of small bio-compatible microspheres
CA1101330A (en) * 1977-09-19 1981-05-19 Ernst A. Fischer Immunological material bonded to carboxylated latex polymer and process for making it
US4278651A (en) * 1978-09-27 1981-07-14 Becton Dickinson & Company Supported receptor and use thereof in an assay
JPS6021370B2 (ja) * 1979-11-05 1985-05-27 富士写真フイルム株式会社 写真感光材料
DE3116995A1 (de) * 1981-04-29 1982-11-25 Röhm GmbH, 6100 Darmstadt Latex zur immobilisierung von biologisch wirksamen substanzen
JPS589688A (ja) * 1981-07-06 1983-01-20 Toyobo Co Ltd 安定な酵素組成物
US4680338A (en) * 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
US4997772A (en) * 1987-09-18 1991-03-05 Eastman Kodak Company Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use
CA1300499C (en) * 1987-08-03 1992-05-12 Susan J. Danielson Water-insoluble reagent, elements containing same and methods of use
US4855219A (en) * 1987-09-18 1989-08-08 Eastman Kodak Company Photographic element having polymer particles covalently bonded to gelatin
DE3921498A1 (de) * 1988-09-28 1990-03-29 Bayer Ag Polymer-gebundene-farbstoffe, verfahren zu deren herstellung und verwendung
US5043062A (en) * 1989-02-21 1991-08-27 Eastman Kodak Company High performance affinity chromatography column comprising non-porous, nondisperse polymeric packing material
US4921654A (en) * 1989-09-18 1990-05-01 Cuno, Incorporated Low protein binding membrane

Also Published As

Publication number Publication date
FI102921B1 (fi) 1999-03-15
HK115297A (en) 1997-08-29
FI920329A (fi) 1992-07-26
EP0496473A3 (en) 1993-01-13
EP0496473A2 (de) 1992-07-29
JP3110839B2 (ja) 2000-11-20
IE920215A1 (en) 1992-07-29
KR100209072B1 (ko) 1999-07-15
JPH0560759A (ja) 1993-03-12
FI920329A0 (fi) 1992-01-24
TW218037B (de) 1993-12-21
ATE150871T1 (de) 1997-04-15
KR920015133A (ko) 1992-08-26
IE980447A1 (en) 2000-11-15
US5308749A (en) 1994-05-03
EP0496473B1 (de) 1997-03-26
CA2058515C (en) 2000-01-18
FI102921B (fi) 1999-03-15
DE69218471D1 (de) 1997-04-30

Similar Documents

Publication Publication Date Title
DE69218471T2 (de) Verfahren zur Herstellung von biologisch aktiven Reagentien aus Succinimid enthaltenden Polymeren, analytisches Element und Verwendungsmethoden
ATE129347T1 (de) Biologisch aktive reagenzien aus carboxylgruppenhaltigen polymerisaten, analytisches element und verfahren zur verwendung.
DE69114394T2 (de) Analytisches Element mit biologisch aktivem Reagens und Verfahren zur Verwendung des Reagens.
DE69409788T2 (de) Methoden fuer analyse/ trennung
EP0458841A4 (en) Method for the use and synthesis of peptides
DE69112216T2 (de) Radialeinlassvorrichtung zur trennung von partikeln.
DK0397113T3 (da) Fremgangsmåde til påvisning af specifikt bindingsdygtige stoffer i legemsvæsker
DE3369078D1 (en) Surface-grafted particulate support, its preparation and adsorbents for affinity-chromatography comprising this support, and its use, especially in biology
DE68929334D1 (de) Verfahren zumm Assay von Endotoxin-Konzentration
PL287102A1 (en) Agent for chromatographic separation containing a ligand, method for manufactoring the agent and a method for appylying the agent to separate synthetic or natural particles from a liquid mixture
DE68925588T2 (de) Verfahren zur aktivierung von polymeren trägern und damit hergestellte zusammensetzungen zur verwendung in der affinitätschromatographie
ATE191568T1 (de) Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
DE59206261D1 (de) Definierte Beschichtung mit rekombinanten Fusionsproteinen aus konstantem Fusionspartner und variablem Antigenanteil in diagnostischen Testsystemen
CA2075695A1 (en) Monoclonal antibodies to sulfonated polymers
CA2053618A1 (en) Assay of Substances Using Flow Cytometry
ATE182215T1 (de) Verfahren zur bestimmung von rheumafaktoren und mittel zur durchführung des verfahrens
CA2081879A1 (en) Monoclonal antibodies to polyacrylate polymers
EP0096520A3 (de) Antigennachweis:Rheumatoide Arthritis
ES2033445T3 (es) Nuevo procedimiento de dosificacion simultaneo de por lo menos dos subconjuntos de apolipoproteinas contenidas en un medio biologico.
ATA253989A (de) Vorrichtung zur anreicherung von analyten aus flüssigen proben

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN