DE69210875D1 - Piperidinderivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung - Google Patents

Piperidinderivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung

Info

Publication number
DE69210875D1
DE69210875D1 DE69210875T DE69210875T DE69210875D1 DE 69210875 D1 DE69210875 D1 DE 69210875D1 DE 69210875 T DE69210875 T DE 69210875T DE 69210875 T DE69210875 T DE 69210875T DE 69210875 D1 DE69210875 D1 DE 69210875D1
Authority
DE
Germany
Prior art keywords
group
alkyl group
cyclo
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69210875T
Other languages
English (en)
Other versions
DE69210875T2 (de
Inventor
Samir Jegham
Gerard Defosse
Thomas Purcell
Johannes Schoemaker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of DE69210875D1 publication Critical patent/DE69210875D1/de
Application granted granted Critical
Publication of DE69210875T2 publication Critical patent/DE69210875T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
DE69210875T 1991-04-03 1992-03-23 Piperidinderivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung Expired - Fee Related DE69210875T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9104009A FR2674855B1 (fr) 1991-04-03 1991-04-03 Derives de piperidine, leur preparation et leur application en therapeutique.

Publications (2)

Publication Number Publication Date
DE69210875D1 true DE69210875D1 (de) 1996-06-27
DE69210875T2 DE69210875T2 (de) 1996-12-05

Family

ID=9411394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69210875T Expired - Fee Related DE69210875T2 (de) 1991-04-03 1992-03-23 Piperidinderivate, Verfahren zu deren Herstellung und deren therapeutische Anwendung

Country Status (19)

Country Link
US (1) US5280030A (de)
EP (1) EP0507650B1 (de)
JP (1) JPH0788378B2 (de)
KR (1) KR920019778A (de)
CN (1) CN1065459A (de)
AT (1) ATE138375T1 (de)
AU (1) AU646332B2 (de)
CA (1) CA2064924A1 (de)
CS (1) CS100192A3 (de)
DE (1) DE69210875T2 (de)
FI (1) FI921459A (de)
FR (1) FR2674855B1 (de)
HU (1) HUT62573A (de)
IE (1) IE921048A1 (de)
IL (1) IL101472A0 (de)
MX (1) MX9201507A (de)
NO (1) NO921281L (de)
NZ (1) NZ242214A (de)
PL (1) PL294088A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993014745A1 (en) * 1992-01-23 1993-08-05 Smithkline Beecham Plc Use of 5-ht4 receptor antagonists as medicaments for treating migraine
US5380858A (en) * 1992-04-01 1995-01-10 The University Of Toledo Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
FR2710915B1 (fr) * 1993-10-04 1995-11-24 Synthelabo Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
FR2731707B1 (fr) * 1995-03-13 1997-04-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2731708B1 (fr) * 1995-03-13 1997-04-30 Synthelabo Derives de piperidine, leur procede de preparation et leur application en therapeutique
FR2765221B1 (fr) * 1997-06-25 1999-07-30 Synthelabo Derives de 4-[(1h-imidazol-4-yl)piperidin-1-yl]anilide, leur preparation et leur application en therapeutique
FR2765580B1 (fr) * 1997-07-01 1999-08-06 Synthelabo Derives de (1h-imidazol-4-yl)piperidine, leur preparation et leur application en therapeutique
FR2772377B1 (fr) * 1997-12-12 2000-01-07 Synthelabo Derives de 1-(1-h-imidazol-2-yl)pyrrolidines et 1-(1-h-imidazol-2-ylpiperidines), leur preparation et leur application en therapeutique
GB9918425D0 (en) * 1999-08-04 1999-10-06 Novartis Ag Organic compounds
US6887870B1 (en) * 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
AU2002346216B2 (en) * 1999-12-27 2005-12-08 Japan Tobacco Inc. Fused cyclic compounds and medicinal use thereof
US6770666B2 (en) 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
ID30204A (id) * 1999-12-27 2001-11-15 Japan Tobacco Inc Senyawa-senyawa cincin terfusi dan penggunaannya sebagai obat
US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
AR035543A1 (es) * 2001-06-26 2004-06-16 Japan Tobacco Inc Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con
CN1829709A (zh) * 2003-08-01 2006-09-06 健亚生物科技公司 对抗黄病毒的双环咪唑衍生物
WO2006076529A1 (en) * 2005-01-14 2006-07-20 Genelabs Technologies, Inc. Indole derivatives for treating viral infections
ES2523459T3 (es) 2005-02-25 2014-11-26 Raqualia Pharma Inc Derivados de benzisoxazol
US9006268B2 (en) * 2010-06-11 2015-04-14 Merck Sharp & Dohme Corp. Prolylcarboxypeptidase inhibitors
DK2688648T3 (en) 2011-03-23 2016-03-14 Raqualia Pharma Inc 5-HT 4 receptor agonist as a prokinetic agent
CA2880299A1 (en) * 2012-07-27 2014-01-30 Bial - Portela & Ca, S.A. Process for the synthesis of substituted urea compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
FR2579596B1 (fr) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
US4879301A (en) * 1987-04-28 1989-11-07 Hoei Pharmaceutical Co., Ltd. Antiallergic and antiinflammatory benzothiazolinone derivatives
FR2658823B1 (fr) * 1990-02-27 1992-04-30 Adir Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .

Also Published As

Publication number Publication date
HUT62573A (en) 1993-05-28
FI921459A0 (fi) 1992-04-02
EP0507650B1 (de) 1996-05-22
JPH05112563A (ja) 1993-05-07
JPH0788378B2 (ja) 1995-09-27
NZ242214A (en) 1993-05-26
IL101472A0 (en) 1992-12-30
FR2674855B1 (fr) 1994-01-14
CA2064924A1 (en) 1992-10-04
NO921281L (no) 1992-10-05
NO921281D0 (no) 1992-04-02
IE921048A1 (en) 1992-10-07
US5280030A (en) 1994-01-18
MX9201507A (es) 1992-10-01
KR920019778A (ko) 1992-11-20
FR2674855A1 (fr) 1992-10-09
CS100192A3 (en) 1992-10-14
AU1398992A (en) 1992-10-08
HU9201116D0 (en) 1992-06-29
ATE138375T1 (de) 1996-06-15
EP0507650A1 (de) 1992-10-07
CN1065459A (zh) 1992-10-21
DE69210875T2 (de) 1996-12-05
PL294088A1 (de) 1993-02-08
AU646332B2 (en) 1994-02-17
FI921459A (fi) 1992-10-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee