ATE117303T1 - Imidazo(1,2-c>chinazolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents

Imidazo(1,2-c>chinazolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Info

Publication number
ATE117303T1
ATE117303T1 AT91400645T AT91400645T ATE117303T1 AT E117303 T1 ATE117303 T1 AT E117303T1 AT 91400645 T AT91400645 T AT 91400645T AT 91400645 T AT91400645 T AT 91400645T AT E117303 T1 ATE117303 T1 AT E117303T1
Authority
AT
Austria
Prior art keywords
optionally substituted
imidazo
amino
hydrogen
production
Prior art date
Application number
AT91400645T
Other languages
English (en)
Inventor
Jean-Jacques Bourguignon
Camille-Georges Wermuth
De La Faverie Jean-Fran Renaud
Catherine Thollon
Alain Lombet
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE117303T1 publication Critical patent/ATE117303T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT91400645T 1990-03-09 1991-03-08 Imidazo(1,2-c>chinazolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. ATE117303T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003003A FR2659329B1 (fr) 1990-03-09 1990-03-09 Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
ATE117303T1 true ATE117303T1 (de) 1995-02-15

Family

ID=9394556

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91400645T ATE117303T1 (de) 1990-03-09 1991-03-08 Imidazo(1,2-c>chinazolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.

Country Status (16)

Country Link
US (1) US5128338A (de)
EP (1) EP0446141B1 (de)
JP (1) JPH07103122B2 (de)
AT (1) ATE117303T1 (de)
AU (1) AU633408B2 (de)
CA (1) CA2037812A1 (de)
DE (1) DE69106746T2 (de)
DK (1) DK0446141T3 (de)
ES (1) ES2069841T3 (de)
FR (1) FR2659329B1 (de)
GR (1) GR3015514T3 (de)
IE (1) IE66181B1 (de)
NZ (1) NZ237363A (de)
OA (1) OA09488A (de)
PT (1) PT96982A (de)
ZA (1) ZA911726B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
US5792766A (en) 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
US6417220B2 (en) 1996-10-01 2002-07-09 Daiichi Pharmaceutical Co., Ltd. Mitochondrial membrane stabilizer
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
ES2268894T3 (es) 1998-12-18 2007-03-16 Scios Inc. Agonistas y antagonistas de receptores de benzodiazepina de tipo periferico.
EP1607744A3 (de) * 1998-12-18 2009-09-30 Scios Inc. Behandlung von zystenbildenden Erkrankungen mit Kombinationen enthaltend PTBR-Agonisten
US6380183B1 (en) * 1998-12-18 2002-04-30 Scios, Inc. Treatment of diseases involving cyst formation
US20050009812A1 (en) * 2001-10-05 2005-01-13 Takuya Seko Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
KR100864364B1 (ko) * 2005-12-13 2008-10-17 주식회사 엘지화학 신규한 이미다조퀴나졸린 유도체, 이의 제조방법 및 이를이용한 유기전기소자
ES2904267T3 (es) * 2012-06-18 2022-04-04 Dart Neuroscience Llc Composiciones farmacéuticas de derivados de 6H-pirido[3.2-e][1.2.4]triazolo[1,5-c]pirimidina-5-ona y[1.2.4]triazolo[1,5-c]pteridina-5(6H)-ona como inhibidores de PDE1 para el tratamiento, por ejemplo, de trastornosneurológicos
JP6420400B2 (ja) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129653A (en) * 1977-01-05 1978-12-12 Ortho Pharmaceutical Corporation Substituted pyrrolo [1,2-c] quinazolines and pharmaceutical compositions and methods employing them
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
NZ237363A (en) 1992-12-23
AU633408B2 (en) 1993-01-28
EP0446141A1 (de) 1991-09-11
ZA911726B (en) 1991-12-24
OA09488A (fr) 1992-11-15
ES2069841T3 (es) 1995-05-16
FR2659329A1 (fr) 1991-09-13
AU7274591A (en) 1991-09-12
PT96982A (pt) 1991-10-31
DE69106746T2 (de) 1995-08-31
JPH07103122B2 (ja) 1995-11-08
DK0446141T3 (da) 1995-05-15
EP0446141B1 (de) 1995-01-18
JPH04217682A (ja) 1992-08-07
DE69106746D1 (de) 1995-03-02
IE66181B1 (en) 1995-12-13
CA2037812A1 (fr) 1991-09-10
FR2659329B1 (fr) 1994-06-03
US5128338A (en) 1992-07-07
IE910770A1 (en) 1991-09-11
GR3015514T3 (en) 1995-06-30

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee