DE69106746T2 - Imidazo[1,2-c]chinazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. - Google Patents

Imidazo[1,2-c]chinazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.

Info

Publication number
DE69106746T2
DE69106746T2 DE69106746T DE69106746T DE69106746T2 DE 69106746 T2 DE69106746 T2 DE 69106746T2 DE 69106746 T DE69106746 T DE 69106746T DE 69106746 T DE69106746 T DE 69106746T DE 69106746 T2 DE69106746 T2 DE 69106746T2
Authority
DE
Germany
Prior art keywords
optionally substituted
amino
hydrogen
imidazo
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69106746T
Other languages
English (en)
Other versions
DE69106746D1 (de
Inventor
Jean-Jacques Bourguignon
Camille-Georges Wermuth
De La Faverie Jean-Fran Renaud
Catherine Thollon
Alain Lombet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69106746D1 publication Critical patent/DE69106746D1/de
Application granted granted Critical
Publication of DE69106746T2 publication Critical patent/DE69106746T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69106746T 1990-03-09 1991-03-08 Imidazo[1,2-c]chinazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. Expired - Fee Related DE69106746T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003003A FR2659329B1 (fr) 1990-03-09 1990-03-09 Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (2)

Publication Number Publication Date
DE69106746D1 DE69106746D1 (de) 1995-03-02
DE69106746T2 true DE69106746T2 (de) 1995-08-31

Family

ID=9394556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69106746T Expired - Fee Related DE69106746T2 (de) 1990-03-09 1991-03-08 Imidazo[1,2-c]chinazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.

Country Status (16)

Country Link
US (1) US5128338A (de)
EP (1) EP0446141B1 (de)
JP (1) JPH07103122B2 (de)
AT (1) ATE117303T1 (de)
AU (1) AU633408B2 (de)
CA (1) CA2037812A1 (de)
DE (1) DE69106746T2 (de)
DK (1) DK0446141T3 (de)
ES (1) ES2069841T3 (de)
FR (1) FR2659329B1 (de)
GR (1) GR3015514T3 (de)
IE (1) IE66181B1 (de)
NZ (1) NZ237363A (de)
OA (1) OA09488A (de)
PT (1) PT96982A (de)
ZA (1) ZA911726B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
US5792766A (en) * 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
WO1998014213A1 (fr) 1996-10-01 1998-04-09 Daiichi Pharmaceutical Co., Ltd. Stabilisateur de la membrane mitochondriale
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
EP1607744A3 (de) * 1998-12-18 2009-09-30 Scios Inc. Behandlung von zystenbildenden Erkrankungen mit Kombinationen enthaltend PTBR-Agonisten
WO2000037085A1 (en) * 1998-12-18 2000-06-29 Scios Inc. Treatment of diseases involving cyst formation
ES2268894T3 (es) 1998-12-18 2007-03-16 Scios Inc. Agonistas y antagonistas de receptores de benzodiazepina de tipo periferico.
EP1438973A4 (de) * 2001-10-05 2005-07-13 Ono Pharmaceutical Co Mittel zur behandlung von stressbedingten erkrankungen mit mitochondrien-benzodiazepin-rezeptorantagonisten
KR100864364B1 (ko) * 2005-12-13 2008-10-17 주식회사 엘지화학 신규한 이미다조퀴나졸린 유도체, 이의 제조방법 및 이를이용한 유기전기소자
BR112014031730B1 (pt) 2012-06-18 2023-05-16 Dart Neuroscience (Cayman) Ltd Compostos ou sais farmaceuticamente aceitáveis dos mesmos e seu uso
JP6420400B2 (ja) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129653A (en) * 1977-01-05 1978-12-12 Ortho Pharmaceutical Corporation Substituted pyrrolo [1,2-c] quinazolines and pharmaceutical compositions and methods employing them
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
ZA911726B (en) 1991-12-24
ES2069841T3 (es) 1995-05-16
AU7274591A (en) 1991-09-12
EP0446141B1 (de) 1995-01-18
DE69106746D1 (de) 1995-03-02
ATE117303T1 (de) 1995-02-15
GR3015514T3 (en) 1995-06-30
FR2659329B1 (fr) 1994-06-03
CA2037812A1 (fr) 1991-09-10
OA09488A (fr) 1992-11-15
IE910770A1 (en) 1991-09-11
US5128338A (en) 1992-07-07
IE66181B1 (en) 1995-12-13
DK0446141T3 (da) 1995-05-15
NZ237363A (en) 1992-12-23
EP0446141A1 (de) 1991-09-11
AU633408B2 (en) 1993-01-28
FR2659329A1 (fr) 1991-09-13
JPH07103122B2 (ja) 1995-11-08
PT96982A (pt) 1991-10-31
JPH04217682A (ja) 1992-08-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee