DE69130494D1 - Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung - Google Patents

Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung

Info

Publication number
DE69130494D1
DE69130494D1 DE69130494T DE69130494T DE69130494D1 DE 69130494 D1 DE69130494 D1 DE 69130494D1 DE 69130494 T DE69130494 T DE 69130494T DE 69130494 T DE69130494 T DE 69130494T DE 69130494 D1 DE69130494 D1 DE 69130494D1
Authority
DE
Germany
Prior art keywords
production
growth factor
recombinant human
hepatocyte growth
human hepatocyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69130494T
Other languages
English (en)
Other versions
DE69130494T2 (de
Inventor
Toshikazu Nakamura
Michio Hagiya
Tatsuya Seki
Manabu Shimonishi
Shin Shimizu
Izumi Ihara
Mariko Sakaguchi
Osamu Asami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69130494D1 publication Critical patent/DE69130494D1/de
Application granted granted Critical
Publication of DE69130494T2 publication Critical patent/DE69130494T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1991630494 1990-06-11 1991-06-07 Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung Expired - Lifetime DE69130494T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15247490 1990-06-11

Publications (2)

Publication Number Publication Date
DE69130494D1 true DE69130494D1 (de) 1998-12-24
DE69130494T2 DE69130494T2 (de) 1999-07-08

Family

ID=15541307

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1991630494 Expired - Lifetime DE69130494T2 (de) 1990-06-11 1991-06-07 Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
DE1991633492 Expired - Lifetime DE69133492T2 (de) 1990-06-11 1991-06-07 Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1991633492 Expired - Lifetime DE69133492T2 (de) 1990-06-11 1991-06-07 Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung

Country Status (3)

Country Link
EP (2) EP0461560B1 (de)
JP (1) JP2000300282A (de)
DE (2) DE69130494T2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
US5316921A (en) * 1992-05-18 1994-05-31 Genentech, Inc. Single-chain hepatocyte growth factor variants
CA2118012A1 (en) * 1992-05-18 1993-11-25 Paul J. Godowski Hepatocyte growth factor variants
DK0821969T3 (da) * 1992-07-16 2007-03-26 Daiichi Seiyaku Co Medicinsk sammensætning omfattende TCF-II
JPH07507328A (ja) * 1992-12-28 1995-08-10 雪印乳業株式会社 Ｔｃｆ変異体
IT1271088B (it) * 1994-11-24 1997-05-26 Dompe Spa Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche
KR100725199B1 (ko) 1995-08-29 2007-08-16 안제스에무지 가부시키가이샤 에이치지에프유전자를함유하는약제
JP4006058B2 (ja) 1997-03-11 2007-11-14 第一三共株式会社 多臓器不全予防及び／又は治療剤
CA2253629A1 (en) 1997-03-14 1998-09-24 Snow Brand Milk Products Co., Ltd. Agent for preventing and/or treating cachexia
EP1074264B1 (de) * 1998-04-28 2008-09-17 Toshikazu Nakamura Inhibitoren für die gefässneubildung
ATE395087T1 (de) 1999-10-08 2008-05-15 Anges Mg Inc Hgf zur gentherapie der karidomyopathie
CA2410762C (en) 2000-05-31 2013-10-15 Masashi Miyake Feline hepatocyte growth factor
EP1297841B1 (de) * 2000-06-02 2010-05-05 Takeda Pharmaceutical Company Limited Promotor der proliferation und inhibitor der apoptose pankreatischer langerhans beta-zellen und screening von anwärter-verbindungen für medikamente
US7129064B2 (en) 2000-06-22 2006-10-31 Nippon Zenyaku Kogyo Ltd. Canine hepatocyte growth factor
KR20020097319A (ko) * 2001-06-20 2002-12-31 윤재승 사람 간세포 성장인자 코딩 벡터, 형질전환 균주 및이로부터 발현된 재조합 단백질
CN103880955A (zh) 2003-07-18 2014-06-25 安姆根有限公司 肝细胞生长因子的特异性结合物
JP4728807B2 (ja) * 2003-09-03 2011-07-20 敏一 中村 ヒト組換えｈｇｆを含有する皮膚潰瘍予防治癒剤
WO2010041716A1 (ja) 2008-10-10 2010-04-15 クリングルファーマ株式会社 腱骨移行部組織または靭帯骨移行部組織の再生促進剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713339A (en) * 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
EP0293785A3 (de) * 1987-05-29 1990-05-02 Oncogen Limited Partnership Klonierung und Expression von transformierendem Affenwachstumsfaktor-SS 1
NZ232813A (en) * 1989-03-10 1992-08-26 Snow Brand Milk Products Co Ltd Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons
CA2022752C (en) * 1989-08-11 1998-07-07 Naomi Kitamura Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor
JPH03204899A (ja) * 1989-09-21 1991-09-06 Otsuka Pharmaceut Co Ltd ヒト肝再生因子、そのｄｎａ塩基配列、該配列を含むプラスミド及び形質転換体並びにリコンビナント肝再生因子

Also Published As

Publication number Publication date
DE69133492D1 (de) 2006-01-05
EP0859009B1 (de) 2005-11-30
JP2000300282A (ja) 2000-10-31
EP0461560A1 (de) 1991-12-18
DE69133492T2 (de) 2006-08-10
EP0461560B1 (de) 1998-11-18
EP0859009A3 (de) 1998-08-26
DE69130494T2 (de) 1999-07-08
EP0859009A2 (de) 1998-08-19

Similar Documents

Publication Publication Date Title
DE69130494T2 (de) Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
DE69115939D1 (de) Magnetkopf und Verfahren zu seiner Herstellung
DE69129746T2 (de) Modifiziertes Polysilazan und Verfahren zu seiner Herstellung
DE69214306D1 (de) Organopentasiloxan und Verfahren zu seiner Herstellung
DE69331176D1 (de) Knochenzement und Verfahren zu seiner Herstellung
ATA241690A (de) Schichtwerkstoff fuer gleitelemente und verfahren zu seiner herstellung
ATA102392A (de) Topisches terbinafinpräparat und verfahren zu seiner herstellung
DE59108665D1 (de) Temperaturfühler und verfahren zur herstellung von temperaturfühlerelementen
DE69225439D1 (de) Verdichter und Verfahren zu seiner Herstellung
DE69429323T2 (de) Poröses keramisches material und verfahren zu seiner herstellung
DE69116599D1 (de) Polyisocyanatoisocyanurat, Verfahren zu seiner Herstellung und seine Verwendung
DE3775294D1 (de) Implantatwerkstoff und verfahren zu seiner herstellung.
DE69123896D1 (de) pH-Messelektrode und Verfahren zur Herstellung derselben
DE69301771D1 (de) T-Butyl-R-(-)-4-cyano-3-hydroxybutyrat und Verfahren zu seiner Herstellung
DE59208880D1 (de) Sauerstoff-Sensor und Verfahren zu seiner Herstellung
DE69009711D1 (de) Reissverschluss und Verfahren zu seiner Herstellung.
DE69328243T2 (de) Filter und verfahren zu seiner herstellung
DE69123642D1 (de) MESFET und Verfahren zur Herstellung
DE69322421D1 (de) Gewebe-Prepreg und Verfahren zu seiner Herstellung
ATA22489A (de) Geschirrspülmittel und verfahren zu seiner herstellung
ATE148446T1 (de) Verfahren zur herstellung von 2- alkoxymethylakrolein und seine verwendung zur herstellung von 3-alkoxymethylchinolinen
DE69122851D1 (de) Hitzebeständiger vliesstoff und verfahren zu seiner herstellung
DE59205668D1 (de) Verlorenes Modell und Verfahren zu seiner Herstellung
DE69121006D1 (de) Polyarylat und Verfahren zu seiner Herstellung
DE69129102D1 (de) Reversibel entfaerbarer spritguss und verfahren zu seiner herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition