DE69133492D1 - Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung - Google Patents
Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner HerstellungInfo
- Publication number
- DE69133492D1 DE69133492D1 DE69133492T DE69133492T DE69133492D1 DE 69133492 D1 DE69133492 D1 DE 69133492D1 DE 69133492 T DE69133492 T DE 69133492T DE 69133492 T DE69133492 T DE 69133492T DE 69133492 D1 DE69133492 D1 DE 69133492D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- growth factor
- recombinant human
- hepatocyte growth
- human hepatocyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101000898034 Homo sapiens Hepatocyte growth factor Proteins 0.000 title 1
- 102000057308 human HGF Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15247490 | 1990-06-11 | ||
JP15247490 | 1990-06-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69133492D1 true DE69133492D1 (de) | 2006-01-05 |
DE69133492T2 DE69133492T2 (de) | 2006-08-10 |
Family
ID=15541307
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1991630494 Expired - Lifetime DE69130494T2 (de) | 1990-06-11 | 1991-06-07 | Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung |
DE1991633492 Expired - Lifetime DE69133492T2 (de) | 1990-06-11 | 1991-06-07 | Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1991630494 Expired - Lifetime DE69130494T2 (de) | 1990-06-11 | 1991-06-07 | Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung |
Country Status (3)
Country | Link |
---|---|
EP (2) | EP0461560B1 (de) |
JP (1) | JP2000300282A (de) |
DE (2) | DE69130494T2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362716A (en) * | 1989-12-27 | 1994-11-08 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines |
US5328837A (en) * | 1992-05-18 | 1994-07-12 | Genentech, Inc. | Hepatocyte growth factor protease domain variants |
US5316921A (en) * | 1992-05-18 | 1994-05-31 | Genentech, Inc. | Single-chain hepatocyte growth factor variants |
CA2118012A1 (en) * | 1992-05-18 | 1993-11-25 | Paul J. Godowski | Hepatocyte growth factor variants |
DK0821969T3 (da) * | 1992-07-16 | 2007-03-26 | Daiichi Seiyaku Co | Medicinsk sammensætning omfattende TCF-II |
JPH07507328A (ja) * | 1992-12-28 | 1995-08-10 | 雪印乳業株式会社 | Tcf変異体 |
IT1271088B (it) * | 1994-11-24 | 1997-05-26 | Dompe Spa | Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche |
KR100725199B1 (ko) | 1995-08-29 | 2007-08-16 | 안제스에무지 가부시키가이샤 | 에이치지에프유전자를함유하는약제 |
JP4006058B2 (ja) | 1997-03-11 | 2007-11-14 | 第一三共株式会社 | 多臓器不全予防及び/又は治療剤 |
CA2253629A1 (en) | 1997-03-14 | 1998-09-24 | Snow Brand Milk Products Co., Ltd. | Agent for preventing and/or treating cachexia |
EP1074264B1 (de) * | 1998-04-28 | 2008-09-17 | Toshikazu Nakamura | Inhibitoren für die gefässneubildung |
ATE395087T1 (de) | 1999-10-08 | 2008-05-15 | Anges Mg Inc | Hgf zur gentherapie der karidomyopathie |
CA2410762C (en) | 2000-05-31 | 2013-10-15 | Masashi Miyake | Feline hepatocyte growth factor |
EP1297841B1 (de) * | 2000-06-02 | 2010-05-05 | Takeda Pharmaceutical Company Limited | Promotor der proliferation und inhibitor der apoptose pankreatischer langerhans beta-zellen und screening von anwärter-verbindungen für medikamente |
US7129064B2 (en) | 2000-06-22 | 2006-10-31 | Nippon Zenyaku Kogyo Ltd. | Canine hepatocyte growth factor |
KR20020097319A (ko) * | 2001-06-20 | 2002-12-31 | 윤재승 | 사람 간세포 성장인자 코딩 벡터, 형질전환 균주 및이로부터 발현된 재조합 단백질 |
CN103880955A (zh) | 2003-07-18 | 2014-06-25 | 安姆根有限公司 | 肝细胞生长因子的特异性结合物 |
JP4728807B2 (ja) * | 2003-09-03 | 2011-07-20 | 敏一 中村 | ヒト組換えhgfを含有する皮膚潰瘍予防治癒剤 |
WO2010041716A1 (ja) | 2008-10-10 | 2010-04-15 | クリングルファーマ株式会社 | 腱骨移行部組織または靭帯骨移行部組織の再生促進剤 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4713339A (en) * | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
EP0293785A3 (de) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Klonierung und Expression von transformierendem Affenwachstumsfaktor-SS 1 |
NZ232813A (en) * | 1989-03-10 | 1992-08-26 | Snow Brand Milk Products Co Ltd | Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons |
CA2022752C (en) * | 1989-08-11 | 1998-07-07 | Naomi Kitamura | Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor |
JPH03204899A (ja) * | 1989-09-21 | 1991-09-06 | Otsuka Pharmaceut Co Ltd | ヒト肝再生因子、そのdna塩基配列、該配列を含むプラスミド及び形質転換体並びにリコンビナント肝再生因子 |
-
1991
- 1991-06-07 EP EP91109369A patent/EP0461560B1/de not_active Expired - Lifetime
- 1991-06-07 DE DE1991630494 patent/DE69130494T2/de not_active Expired - Lifetime
- 1991-06-07 DE DE1991633492 patent/DE69133492T2/de not_active Expired - Lifetime
- 1991-06-07 EP EP98108130A patent/EP0859009B1/de not_active Expired - Lifetime
-
2000
- 2000-04-07 JP JP2000107213A patent/JP2000300282A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE69130494D1 (de) | 1998-12-24 |
EP0859009B1 (de) | 2005-11-30 |
JP2000300282A (ja) | 2000-10-31 |
EP0461560A1 (de) | 1991-12-18 |
DE69133492T2 (de) | 2006-08-10 |
EP0461560B1 (de) | 1998-11-18 |
EP0859009A3 (de) | 1998-08-26 |
DE69130494T2 (de) | 1999-07-08 |
EP0859009A2 (de) | 1998-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: NAKAMURA, TOSHIKAZU, KYOTO, JP |
|
8364 | No opposition during term of opposition |