IT1271088B - Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche - Google Patents

Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche

Info

Publication number
IT1271088B
IT1271088B ITMI942382A ITMI942382A IT1271088B IT 1271088 B IT1271088 B IT 1271088B IT MI942382 A ITMI942382 A IT MI942382A IT MI942382 A ITMI942382 A IT MI942382A IT 1271088 B IT1271088 B IT 1271088B
Authority
IT
Italy
Prior art keywords
hematopoietic cells
proliferation
differentiation
growth factor
hepatocyte growth
Prior art date
Application number
ITMI942382A
Other languages
English (en)
Inventor
Paolo Comoglio
Original Assignee
Dompe Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Spa filed Critical Dompe Spa
Publication of ITMI942382A0 publication Critical patent/ITMI942382A0/it
Priority to ITMI942382A priority Critical patent/IT1271088B/it
Priority to PCT/EP1995/004589 priority patent/WO1996015802A1/en
Priority to AU42996/96A priority patent/AU707259B2/en
Priority to DK95941620T priority patent/DK0793503T3/da
Priority to ES95941620T priority patent/ES2183890T3/es
Priority to DE69528473T priority patent/DE69528473T2/de
Priority to CA002205914A priority patent/CA2205914C/en
Priority to EP95941620A priority patent/EP0793503B1/en
Priority to US08/836,896 priority patent/US5968501A/en
Priority to PT95941620T priority patent/PT793503E/pt
Priority to AT95941620T priority patent/ATE225183T1/de
Priority to JP51657696A priority patent/JP3874024B2/ja
Publication of ITMI942382A1 publication Critical patent/ITMI942382A1/it
Application granted granted Critical
Publication of IT1271088B publication Critical patent/IT1271088B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Abstract

Si descrive l'uso del fattore di crescita degli epatociti per la preparazione dei medicamenti utili per indurre la proliferazione e la differenziazione di cellule emopoietiche, in particolare di progenitori di cellule emopoietiche multipotenti e eritroidi.
ITMI942382A 1994-11-24 1994-11-24 Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche IT1271088B (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
ITMI942382A IT1271088B (it) 1994-11-24 1994-11-24 Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche
CA002205914A CA2205914C (en) 1994-11-24 1995-11-22 Use of the hepatocyte growth factor to induce proliferation and differentiation of hemopoietic cells
US08/836,896 US5968501A (en) 1994-11-24 1995-11-22 Hepatocyte growth factor--induced proliferation and differentiation of erythroid cells
DK95941620T DK0793503T3 (da) 1994-11-24 1995-11-22 Anvendelse af hepatocyt-vækstfaktor til inducering af profilerering og differentiering af hemotopoietiske celler
ES95941620T ES2183890T3 (es) 1994-11-24 1995-11-22 Uso del factor de crecimiento de hepatocitos para in estimular la proliferacion y diferenciacion de celulas hematopoyeticas.
DE69528473T DE69528473T2 (de) 1994-11-24 1995-11-22 Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
PCT/EP1995/004589 WO1996015802A1 (en) 1994-11-24 1995-11-22 Use of the hepatocyte growth factor to induce proliferation and differentiation of hemopoietic cells
EP95941620A EP0793503B1 (en) 1994-11-24 1995-11-22 Use of the hepatocyte growth factor to induce proliferation and differentiation of hemopoietic cells
AU42996/96A AU707259B2 (en) 1994-11-24 1995-11-22 Use of the hepatocyte growth factor to induce proliferation and differentiation of hemopoietic cells
PT95941620T PT793503E (pt) 1994-11-24 1995-11-22 Uso do factor de crescimento dos hepatocitos para induzir a proliferacao e diferenciacao de celulas henatopoieticas
AT95941620T ATE225183T1 (de) 1994-11-24 1995-11-22 Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
JP51657696A JP3874024B2 (ja) 1994-11-24 1995-11-22 造血細胞の増殖および分化を誘導するための肝細胞増殖因子の使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI942382A IT1271088B (it) 1994-11-24 1994-11-24 Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche

Publications (3)

Publication Number Publication Date
ITMI942382A0 ITMI942382A0 (it) 1994-11-24
ITMI942382A1 ITMI942382A1 (it) 1996-05-24
IT1271088B true IT1271088B (it) 1997-05-26

Family

ID=11369904

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI942382A IT1271088B (it) 1994-11-24 1994-11-24 Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche

Country Status (12)

Country Link
US (1) US5968501A (it)
EP (1) EP0793503B1 (it)
JP (1) JP3874024B2 (it)
AT (1) ATE225183T1 (it)
AU (1) AU707259B2 (it)
CA (1) CA2205914C (it)
DE (1) DE69528473T2 (it)
DK (1) DK0793503T3 (it)
ES (1) ES2183890T3 (it)
IT (1) IT1271088B (it)
PT (1) PT793503E (it)
WO (1) WO1996015802A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004227205B2 (en) * 2003-04-08 2010-06-10 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
EP1702062A2 (en) * 2003-06-11 2006-09-20 Jan Remmereit Differentiation of stem cells for therapeutic use
CN1929856B (zh) * 2004-03-09 2010-11-10 克霖固鲁制药股份有限公司 促进诱导血管分化的含肝细胞生长因子的制剂
JP4797186B2 (ja) * 2004-10-08 2011-10-19 剛史 汐田 末梢血中への造血幹細胞動員剤
US9664671B2 (en) 2012-07-24 2017-05-30 Nissan Chemical Industries, Ltd. Culture medium composition and method of culturing cell or tissue using thereof
US10017805B2 (en) 2012-08-23 2018-07-10 Nissan Chemical Industries, Ltd. Enhancing ingredients for protein production from various cells
EP2987852A4 (en) * 2013-04-17 2016-09-07 Nissan Chemical Ind Ltd MIDDLE COMPOSITION AND PROCESS FOR PRODUCING RED GLOBLES USING THE SAME

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
EP0859009B1 (en) * 1990-06-11 2005-11-30 Toshikazu Nakamura Recombinant human hepatocyte growth factor and method for production thereof
DE69131069T2 (de) * 1990-07-13 1999-07-15 Snow Brand Milk Products Co Ltd Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung
WO1993003061A1 (en) * 1991-07-26 1993-02-18 Toray Industries, Incorporated Hematopoietic stem cell multiplier
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
US5599703A (en) * 1993-10-28 1997-02-04 The United States Of America As Represented By The Secretary Of The Navy In vitro amplification/expansion of CD34+ stem and progenitor cells

Also Published As

Publication number Publication date
WO1996015802A1 (en) 1996-05-30
DE69528473D1 (de) 2002-11-07
JPH10509951A (ja) 1998-09-29
AU4299696A (en) 1996-06-17
ATE225183T1 (de) 2002-10-15
JP3874024B2 (ja) 2007-01-31
ITMI942382A0 (it) 1994-11-24
CA2205914A1 (en) 1996-05-30
DE69528473T2 (de) 2003-07-10
AU707259B2 (en) 1999-07-08
DK0793503T3 (da) 2003-02-03
ES2183890T3 (es) 2003-04-01
PT793503E (pt) 2003-02-28
CA2205914C (en) 2009-04-07
EP0793503B1 (en) 2002-10-02
ITMI942382A1 (it) 1996-05-24
US5968501A (en) 1999-10-19
EP0793503A1 (en) 1997-09-10

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971126