ES2183890T3 - Uso del factor de crecimiento de hepatocitos para in estimular la proliferacion y diferenciacion de celulas hematopoyeticas. - Google Patents

Uso del factor de crecimiento de hepatocitos para in estimular la proliferacion y diferenciacion de celulas hematopoyeticas.

Info

Publication number
ES2183890T3
ES2183890T3 ES95941620T ES95941620T ES2183890T3 ES 2183890 T3 ES2183890 T3 ES 2183890T3 ES 95941620 T ES95941620 T ES 95941620T ES 95941620 T ES95941620 T ES 95941620T ES 2183890 T3 ES2183890 T3 ES 2183890T3
Authority
ES
Spain
Prior art keywords
hepatocits
proliferation
differentiation
growth factor
stimulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95941620T
Other languages
English (en)
Inventor
Paolo M Comoglio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe SpA
Original Assignee
Dompe SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe SpA filed Critical Dompe SpA
Application granted granted Critical
Publication of ES2183890T3 publication Critical patent/ES2183890T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Abstract

USO DEL FACTOR DE CRECIMIENTO DE HEPATOCITOS PARA LA PREPARACION DE MEDICAMENTOS UTILES PARA INDUCIR LA PROLIFERACION Y DIFERENCIACION DE CELULAS HEMOPOYETICAS, ESPECIALMENTE PROGENITORES DE CELULAS HEMOPOYETICAS EROTROIDES Y MULTIPOTENTES.
ES95941620T 1994-11-24 1995-11-22 Uso del factor de crecimiento de hepatocitos para in estimular la proliferacion y diferenciacion de celulas hematopoyeticas. Expired - Lifetime ES2183890T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI942382A IT1271088B (it) 1994-11-24 1994-11-24 Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche

Publications (1)

Publication Number Publication Date
ES2183890T3 true ES2183890T3 (es) 2003-04-01

Family

ID=11369904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95941620T Expired - Lifetime ES2183890T3 (es) 1994-11-24 1995-11-22 Uso del factor de crecimiento de hepatocitos para in estimular la proliferacion y diferenciacion de celulas hematopoyeticas.

Country Status (12)

Country Link
US (1) US5968501A (es)
EP (1) EP0793503B1 (es)
JP (1) JP3874024B2 (es)
AT (1) ATE225183T1 (es)
AU (1) AU707259B2 (es)
CA (1) CA2205914C (es)
DE (1) DE69528473T2 (es)
DK (1) DK0793503T3 (es)
ES (1) ES2183890T3 (es)
IT (1) IT1271088B (es)
PT (1) PT793503E (es)
WO (1) WO1996015802A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2519975C (en) * 2003-04-08 2013-07-02 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
WO2006040615A2 (en) * 2003-06-11 2006-04-20 Jan Remmereit Differenciation of stem cells for therapeutic use
CN1929856B (zh) * 2004-03-09 2010-11-10 克霖固鲁制药股份有限公司 促进诱导血管分化的含肝细胞生长因子的制剂
JP4797186B2 (ja) * 2004-10-08 2011-10-19 剛史 汐田 末梢血中への造血幹細胞動員剤
US9664671B2 (en) 2012-07-24 2017-05-30 Nissan Chemical Industries, Ltd. Culture medium composition and method of culturing cell or tissue using thereof
US10017805B2 (en) 2012-08-23 2018-07-10 Nissan Chemical Industries, Ltd. Enhancing ingredients for protein production from various cells
EP2987852A4 (en) * 2013-04-17 2016-09-07 Nissan Chemical Ind Ltd MIDDLE COMPOSITION AND PROCESS FOR PRODUCING RED GLOBLES USING THE SAME

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
DE69133492T2 (de) * 1990-06-11 2006-08-10 Nakamura, Toshikazu Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
DE69131069T2 (de) * 1990-07-13 1999-07-15 Snow Brand Milk Products Co Ltd Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung
EP0550769B1 (en) * 1991-07-26 2000-04-05 Toray Industries, Inc. Use of hepatocyte growth factors for the manufacture of a hemopoietic stem cell augmenting agent
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
US5599703A (en) * 1993-10-28 1997-02-04 The United States Of America As Represented By The Secretary Of The Navy In vitro amplification/expansion of CD34+ stem and progenitor cells

Also Published As

Publication number Publication date
DE69528473T2 (de) 2003-07-10
ITMI942382A1 (it) 1996-05-24
ITMI942382A0 (it) 1994-11-24
ATE225183T1 (de) 2002-10-15
CA2205914C (en) 2009-04-07
DK0793503T3 (da) 2003-02-03
AU707259B2 (en) 1999-07-08
EP0793503B1 (en) 2002-10-02
IT1271088B (it) 1997-05-26
WO1996015802A1 (en) 1996-05-30
JPH10509951A (ja) 1998-09-29
EP0793503A1 (en) 1997-09-10
DE69528473D1 (de) 2002-11-07
JP3874024B2 (ja) 2007-01-31
CA2205914A1 (en) 1996-05-30
PT793503E (pt) 2003-02-28
US5968501A (en) 1999-10-19
AU4299696A (en) 1996-06-17

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