ES471900A1 - Procedimiento para preparar oxialquilenos polimeros - Google Patents

Procedimiento para preparar oxialquilenos polimeros

Info

Publication number
ES471900A1
ES471900A1 ES471900A ES471900A ES471900A1 ES 471900 A1 ES471900 A1 ES 471900A1 ES 471900 A ES471900 A ES 471900A ES 471900 A ES471900 A ES 471900A ES 471900 A1 ES471900 A1 ES 471900A1
Authority
ES
Spain
Prior art keywords
preparation
absorption inhibitors
lipid absorption
lipid
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471900A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES471900A1 publication Critical patent/ES471900A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
    • C08G65/2606—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups
    • C08G65/2609—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups containing aliphatic hydroxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

Procedimiento para preparar oxialquilenos polímeros, de estructura general: **(fórmula)** en la cual X, Y y Z se eligen de tal modo que resulte un peso molecular de 3.000 a 5.000, la proporción de óxido de propileno sea de un 60 a 80% y la proporción de óxido de etileno de un 20 a 40%; caracterizado porque se hace reaccionar propilenglicol, en presencia de un hidróxido alcalino, primeramente con óxido de propileno y luego con una cantidad correspondiente de óxido de etileno, eliminándose el dióxido alcalino, una vez neutralizado con un ácido mineral, por filtración de la sal.
ES471900A 1977-07-21 1978-07-20 Procedimiento para preparar oxialquilenos polimeros Expired ES471900A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772732929 DE2732929A1 (de) 1977-07-21 1977-07-21 Polyaether, verfahren zu ihrer herstellung sowie ihre verwendung als lipidabsorptionshemmer

Publications (1)

Publication Number Publication Date
ES471900A1 true ES471900A1 (es) 1979-02-01

Family

ID=6014492

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471900A Expired ES471900A1 (es) 1977-07-21 1978-07-20 Procedimiento para preparar oxialquilenos polimeros

Country Status (13)

Country Link
EP (1) EP0000704A1 (es)
JP (1) JPS5422497A (es)
AU (1) AU3806878A (es)
CA (1) CA1111453A (es)
DE (1) DE2732929A1 (es)
DK (1) DK324678A (es)
ES (1) ES471900A1 (es)
FI (1) FI782284A (es)
IL (1) IL55160A0 (es)
IT (1) IT1097831B (es)
NO (1) NO782332L (es)
PT (1) PT68307A (es)
ZA (1) ZA784129B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2850058A1 (de) * 1978-11-18 1980-05-29 Bayer Ag Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2916668A1 (de) * 1979-04-25 1980-11-13 Basf Ag Formmassen, enthaltend styrolacrylnitril-copolymerisate und aethylenoxid-/pro- pylenoxid-dreiblockcopolymerisate, verwendung derselben und formteile aus solchen mischungen
JPS6030650B2 (ja) * 1979-10-26 1985-07-17 日本油脂株式会社 座薬基剤組成物
DE3234084A1 (de) * 1982-09-14 1984-03-15 B. Braun Melsungen Ag, 3508 Melsungen Pharmazeutische zubereitungen zur behandlung von unerwuenschten verwachsungen sowie deren verwendung
DE3420708C1 (de) * 1984-06-02 1985-07-18 Hoechst Ag, 6230 Frankfurt Modifizierte Polyethylenglykole
US5811088A (en) * 1987-02-20 1998-09-22 Emory University Antiinfective compounds and methods of use
DE3875871T2 (de) * 1987-02-20 1993-04-01 Univ Emory Antiinfektioese verbindungen und verfahren zur verwendung.
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
US7202225B1 (en) 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
US6933286B2 (en) 1991-03-19 2005-08-23 R. Martin Emanuele Therapeutic delivery compositions and methods of use thereof
JP2647556B2 (ja) * 1991-03-19 1997-08-27 サイトアーレクス・コーポレーシヨン 改良された生物学的活性を有するポリオキシプロピレン／ポリオキシエチレン共重合体類
USRE38558E1 (en) 1991-03-19 2004-07-20 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
EP0907666A1 (en) 1996-06-27 1999-04-14 G.D. Searle & Co. Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB610505A (en) * 1944-02-08 1948-10-18 Carbide & Carbon Chem Corp A method for making polyoxyalkylene glycols
FR1116M (fr) * 1961-02-02 1962-02-12 Bernard Andre Francois Mirande Utilisation de substances tensio-actives provenant de la condensation de l'oxyde d'éthylene sur les propylenes-glycols dans la résorption des oedemes locaux ou tissulaires systématisés.
ES334486A1 (es) * 1965-12-23 1967-11-01 Smith Kline & French Laboratories Un procedimiento para la preparacion de una composicion farmaceutica que comprende la mezcla de un polimero de polioxipropileno-polioxietileno.

Also Published As

Publication number Publication date
AU3806878A (en) 1980-01-17
JPS5422497A (en) 1979-02-20
ZA784129B (en) 1979-07-25
EP0000704A1 (de) 1979-02-21
FI782284A (fi) 1979-01-22
CA1111453A (en) 1981-10-27
DE2732929A1 (de) 1979-02-01
IT1097831B (it) 1985-08-31
IL55160A0 (en) 1978-09-29
PT68307A (de) 1978-08-01
DK324678A (da) 1979-01-22
IT7825897A0 (it) 1978-07-19
NO782332L (no) 1979-01-23

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