CA1111453A - Polyether compounds, their production and their medicinal use - Google Patents

Polyether compounds, their production and their medicinal use

Info

Publication number
CA1111453A
CA1111453A CA307,799A CA307799A CA1111453A CA 1111453 A CA1111453 A CA 1111453A CA 307799 A CA307799 A CA 307799A CA 1111453 A CA1111453 A CA 1111453A
Authority
CA
Canada
Prior art keywords
compound
process according
reaction
ethylene oxide
alkali metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA307,799A
Other languages
English (en)
French (fr)
Inventor
Gerd Steinert
Harald Horstmann
Rudiger Sitt
Hans P. Krause
Walter Puls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA1111453A publication Critical patent/CA1111453A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
    • C08G65/2606—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups
    • C08G65/2609—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups containing aliphatic hydroxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyethers (AREA)
CA307,799A 1977-07-21 1978-07-20 Polyether compounds, their production and their medicinal use Expired CA1111453A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2732929.9 1977-07-21
DE19772732929 DE2732929A1 (de) 1977-07-21 1977-07-21 Polyaether, verfahren zu ihrer herstellung sowie ihre verwendung als lipidabsorptionshemmer

Publications (1)

Publication Number Publication Date
CA1111453A true CA1111453A (en) 1981-10-27

Family

ID=6014492

Family Applications (1)

Application Number Title Priority Date Filing Date
CA307,799A Expired CA1111453A (en) 1977-07-21 1978-07-20 Polyether compounds, their production and their medicinal use

Country Status (13)

Country Link
EP (1) EP0000704A1 (es)
JP (1) JPS5422497A (es)
AU (1) AU3806878A (es)
CA (1) CA1111453A (es)
DE (1) DE2732929A1 (es)
DK (1) DK324678A (es)
ES (1) ES471900A1 (es)
FI (1) FI782284A (es)
IL (1) IL55160A0 (es)
IT (1) IT1097831B (es)
NO (1) NO782332L (es)
PT (1) PT68307A (es)
ZA (1) ZA784129B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6383500B1 (en) 1996-06-27 2002-05-07 Washington University Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2850058A1 (de) * 1978-11-18 1980-05-29 Bayer Ag Polyaether-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2916668A1 (de) * 1979-04-25 1980-11-13 Basf Ag Formmassen, enthaltend styrolacrylnitril-copolymerisate und aethylenoxid-/pro- pylenoxid-dreiblockcopolymerisate, verwendung derselben und formteile aus solchen mischungen
JPS6030650B2 (ja) 1979-10-26 1985-07-17 日本油脂株式会社 座薬基剤組成物
DE3234084A1 (de) * 1982-09-14 1984-03-15 B. Braun Melsungen Ag, 3508 Melsungen Pharmazeutische zubereitungen zur behandlung von unerwuenschten verwachsungen sowie deren verwendung
DE3420708C1 (de) * 1984-06-02 1985-07-18 Hoechst Ag, 6230 Frankfurt Modifizierte Polyethylenglykole
AU1396588A (en) * 1987-02-20 1988-09-14 Emory University Antiinfective compounds and method of use
US5674911A (en) * 1987-02-20 1997-10-07 Cytrx Corporation Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
US5811088A (en) * 1987-02-20 1998-09-22 Emory University Antiinfective compounds and methods of use
US7202225B1 (en) 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
CA2106474C (en) 1991-03-19 2004-02-10 R. Martin Emanuele Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US6933286B2 (en) 1991-03-19 2005-08-23 R. Martin Emanuele Therapeutic delivery compositions and methods of use thereof
USRE38558E1 (en) 1991-03-19 2004-07-20 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB610505A (en) * 1944-02-08 1948-10-18 Carbide & Carbon Chem Corp A method for making polyoxyalkylene glycols
FR1116M (fr) * 1961-02-02 1962-02-12 Bernard Andre Francois Mirande Utilisation de substances tensio-actives provenant de la condensation de l'oxyde d'éthylene sur les propylenes-glycols dans la résorption des oedemes locaux ou tissulaires systématisés.
ES334486A1 (es) * 1965-12-23 1967-11-01 Smith Kline & French Laboratories Un procedimiento para la preparacion de una composicion farmaceutica que comprende la mezcla de un polimero de polioxipropileno-polioxietileno.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6383500B1 (en) 1996-06-27 2002-05-07 Washington University Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications
US6491903B1 (en) 1996-06-27 2002-12-10 Washington University Particles comprising amphiphilic copolymers

Also Published As

Publication number Publication date
ZA784129B (en) 1979-07-25
DK324678A (da) 1979-01-22
EP0000704A1 (de) 1979-02-21
NO782332L (no) 1979-01-23
JPS5422497A (en) 1979-02-20
IT1097831B (it) 1985-08-31
AU3806878A (en) 1980-01-17
IT7825897A0 (it) 1978-07-19
FI782284A (fi) 1979-01-22
DE2732929A1 (de) 1979-02-01
ES471900A1 (es) 1979-02-01
IL55160A0 (en) 1978-09-29
PT68307A (de) 1978-08-01

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Legal Events

Date Code Title Description
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