DE69125595D1 - Kombination von hyaluronsäure mit einem medizinischen bestandteil, und seine herstellung - Google Patents

Kombination von hyaluronsäure mit einem medizinischen bestandteil, und seine herstellung

Info

Publication number
DE69125595D1
DE69125595D1 DE69125595T DE69125595T DE69125595D1 DE 69125595 D1 DE69125595 D1 DE 69125595D1 DE 69125595 T DE69125595 T DE 69125595T DE 69125595 T DE69125595 T DE 69125595T DE 69125595 D1 DE69125595 D1 DE 69125595D1
Authority
DE
Germany
Prior art keywords
production
combination
hyaluronic acid
medical ingredient
ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69125595T
Other languages
English (en)
Other versions
DE69125595T2 (de
Inventor
Kazuo Akima
Yuhei Iwata
Kayoko Matsuo
Nobutoshi Watari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Application granted granted Critical
Publication of DE69125595D1 publication Critical patent/DE69125595D1/de
Publication of DE69125595T2 publication Critical patent/DE69125595T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
DE69125595T 1990-10-18 1991-10-18 Kombination von hyaluronsäure mit einem medizinischen bestandteil, und seine herstellung Expired - Fee Related DE69125595T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28062890 1990-10-18
JP15961191 1991-06-03
PCT/JP1991/001431 WO1992006714A1 (en) 1990-10-18 1991-10-18 Combination of hyaluronic acid with medicinal ingredient and production thereof

Publications (2)

Publication Number Publication Date
DE69125595D1 true DE69125595D1 (de) 1997-05-15
DE69125595T2 DE69125595T2 (de) 1997-11-13

Family

ID=26486349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125595T Expired - Fee Related DE69125595T2 (de) 1990-10-18 1991-10-18 Kombination von hyaluronsäure mit einem medizinischen bestandteil, und seine herstellung

Country Status (5)

Country Link
EP (1) EP0506976B1 (de)
AU (1) AU652784B2 (de)
CA (1) CA2070672C (de)
DE (1) DE69125595T2 (de)
WO (1) WO1992006714A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994019376A1 (en) * 1993-02-26 1994-09-01 Drug Delivery System Institute, Ltd. Polysaccharide derivative and drug carrier
KR20010025040A (ko) * 1998-05-20 2001-03-26 나가야마 오사무 관절질환 치료제 및 히알루론산의 결합체
ITPD980169A1 (it) * 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
JP2001081103A (ja) * 1999-09-13 2001-03-27 Denki Kagaku Kogyo Kk ヒアルロン酸結合薬剤
DE10151158B4 (de) * 2001-10-19 2004-07-29 Esplora GmbH c/o TU Darmstadt Institut für Biochemie Verbindungen zur Markierung von Zellmembranproteinen
ITPD20020271A1 (it) * 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
KR101142583B1 (ko) * 2004-01-07 2012-05-11 세이가가쿠 고교 가부시키가이샤 히알루론산 유도체 및 그것을 포함하는 약제
ITPD20050056A1 (it) 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
ITPD20050242A1 (it) * 2005-08-03 2007-02-04 Fidia Farmaceutici Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico
EP2242514B1 (de) * 2008-01-30 2015-09-30 University Of Kansas Wirkstoffträger für intralymphatische chemotherapie
EP2279006B1 (de) * 2008-04-22 2014-10-22 FIDIA FARMACEUTICI S.p.A. Therapeutische anwendung von pharmazeutischen zubereitungen mit antitumoralen arzneimitteln, die an hyaluronsäure gebunden sind, bei der behandlung von neoplasien
WO2012118189A1 (ja) 2011-03-03 2012-09-07 中外製薬株式会社 アミノ－カルボン酸により修飾されたヒアルロン酸誘導体
CA2884142C (en) 2012-09-05 2020-11-10 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid derivative having amino acid and steryl group introduced thereinto
US11512147B2 (en) 2017-11-15 2022-11-29 Chugai Seiyaku Kabushiki Kaisha Hyaluronic acid derivative modified with polyethylene glycol

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045163B2 (ja) * 1977-07-01 1985-10-08 協和醗酵工業株式会社 新規組成物
JPS61229816A (ja) * 1985-04-04 1986-10-14 Koken:Kk 医薬徐放剤
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
US4808576A (en) * 1986-04-28 1989-02-28 Mobay Corporation Remote administration of hyaluronic acid to mammals
JPS63264427A (ja) * 1986-12-17 1988-11-01 Green Cross Corp:The 制癌作用物質複合体
US4857505A (en) * 1987-03-09 1989-08-15 American Cyanamid Company Sustained release compositions for parenteral administration and their use
GB8713662D0 (en) * 1987-06-11 1987-07-15 Skandigen Ab Hyaluronic acid derivatives
JPH01287041A (ja) * 1988-05-13 1989-11-17 Rooman Kogyo:Kk 徐放性製剤
SE8804164A0 (sv) * 1988-11-17 1990-05-18 Per Prisell Farmaceutisk beredning
JPH02231078A (ja) * 1989-03-03 1990-09-13 Ube Ind Ltd ヒアルロン酸修飾スーパーオキシドジスムターゼ
EP0416250A3 (en) * 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid
CA1340994C (en) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease

Also Published As

Publication number Publication date
AU8714091A (en) 1992-05-20
EP0506976B1 (de) 1997-04-09
CA2070672A1 (en) 1992-04-19
EP0506976A4 (en) 1993-03-24
CA2070672C (en) 2002-10-08
WO1992006714A1 (en) 1992-04-30
DE69125595T2 (de) 1997-11-13
AU652784B2 (en) 1994-09-08
EP0506976A1 (de) 1992-10-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee