DE68914161T2 - Herstellung von prodrogen. - Google Patents

Herstellung von prodrogen.

Info

Publication number
DE68914161T2
DE68914161T2 DE68914161T DE68914161T DE68914161T2 DE 68914161 T2 DE68914161 T2 DE 68914161T2 DE 68914161 T DE68914161 T DE 68914161T DE 68914161 T DE68914161 T DE 68914161T DE 68914161 T2 DE68914161 T2 DE 68914161T2
Authority
DE
Germany
Prior art keywords
products
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68914161T
Other languages
English (en)
Other versions
DE68914161D1 (de
Inventor
Caroline Springer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Campaign Technology Ltd
Original Assignee
Cancer Research Campaign Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Campaign Technology Ltd filed Critical Cancer Research Campaign Technology Ltd
Publication of DE68914161D1 publication Critical patent/DE68914161D1/de
Application granted granted Critical
Publication of DE68914161T2 publication Critical patent/DE68914161T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
DE68914161T 1988-09-05 1989-09-05 Herstellung von prodrogen. Expired - Fee Related DE68914161T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888820850A GB8820850D0 (en) 1988-09-05 1988-09-05 Improvements relating to pro-drugs
PCT/GB1989/001042 WO1990002729A1 (en) 1988-09-05 1989-09-05 Improvements relating to the production of prodrugs

Publications (2)

Publication Number Publication Date
DE68914161D1 DE68914161D1 (de) 1994-04-28
DE68914161T2 true DE68914161T2 (de) 1994-10-20

Family

ID=10643118

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68914161T Expired - Fee Related DE68914161T2 (de) 1988-09-05 1989-09-05 Herstellung von prodrogen.

Country Status (6)

Country Link
US (1) US5359120A (de)
EP (1) EP0433360B1 (de)
JP (1) JP2642998B2 (de)
DE (1) DE68914161T2 (de)
GB (1) GB8820850D0 (de)
WO (1) WO1990002729A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314960D0 (en) * 1992-07-23 1993-09-01 Zeneca Ltd Chemical compounds
GB9415167D0 (en) 1994-07-27 1994-09-14 Springer Caroline J Improvements relating to cancer therapy
GB9907414D0 (en) 1999-03-31 1999-05-26 Cancer Res Campaign Tech Improvements relating to prodrugs
GB0220319D0 (en) 2002-09-02 2002-10-09 Cancer Res Campaign Tech Enzyme activated self-immolative nitrogen mustard drugs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750155A (en) * 1953-03-17 1956-06-13 Nat Res Dev Substituted alanines

Also Published As

Publication number Publication date
JPH04500517A (ja) 1992-01-30
WO1990002729A1 (en) 1990-03-22
JP2642998B2 (ja) 1997-08-20
US5359120A (en) 1994-10-25
EP0433360B1 (de) 1994-03-23
DE68914161D1 (de) 1994-04-28
EP0433360A1 (de) 1991-06-26
GB8820850D0 (en) 1988-10-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee