DE69125073T2 - Methode zur Reinigung von Ibuprofen enthaltenden Gemischen - Google Patents

Methode zur Reinigung von Ibuprofen enthaltenden Gemischen

Info

Publication number
DE69125073T2
DE69125073T2 DE69125073T DE69125073T DE69125073T2 DE 69125073 T2 DE69125073 T2 DE 69125073T2 DE 69125073 T DE69125073 T DE 69125073T DE 69125073 T DE69125073 T DE 69125073T DE 69125073 T2 DE69125073 T2 DE 69125073T2
Authority
DE
Germany
Prior art keywords
ibuprofen
crystallization
mixture
mixtures containing
containing ibuprofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69125073T
Other languages
English (en)
Other versions
DE69125073D1 (de
Inventor
Edward G Zey
Thomas H Shockley
Debra A Ryan
Gary L Moss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CNA Holdings LLC
Original Assignee
Hoechst Celanese Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Celanese Corp filed Critical Hoechst Celanese Corp
Application granted granted Critical
Publication of DE69125073D1 publication Critical patent/DE69125073D1/de
Publication of DE69125073T2 publication Critical patent/DE69125073T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69125073T 1990-09-06 1991-09-06 Methode zur Reinigung von Ibuprofen enthaltenden Gemischen Expired - Lifetime DE69125073T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/579,427 US5151551A (en) 1990-09-06 1990-09-06 Method for purification of ibuprofen comprising mixtures

Publications (2)

Publication Number Publication Date
DE69125073D1 DE69125073D1 (de) 1997-04-17
DE69125073T2 true DE69125073T2 (de) 1997-06-19

Family

ID=24316864

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125073T Expired - Lifetime DE69125073T2 (de) 1990-09-06 1991-09-06 Methode zur Reinigung von Ibuprofen enthaltenden Gemischen

Country Status (10)

Country Link
US (1) US5151551A (de)
EP (1) EP0474509B1 (de)
AT (1) ATE149995T1 (de)
BR (1) BR9103858A (de)
CA (1) CA2050709C (de)
DE (1) DE69125073T2 (de)
DK (1) DK0474509T3 (de)
ES (1) ES2100212T3 (de)
GR (1) GR3022805T3 (de)
MX (1) MX9100983A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300301A (en) * 1992-12-02 1994-04-05 Hoechst Celanese Corporation Isolation of ibuprofen from tablets
US20060252938A1 (en) * 2003-04-28 2006-11-09 Basf Aktiengesellschaft Process for the separation of palladium catalyst from crude reaction mixtures of aryl acetic acids obtained by carbonylation
WO2015163832A1 (en) 2014-04-25 2015-10-29 Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. An ibuprofen and famotidine combined composition having improved stability
CN112433016A (zh) * 2020-12-11 2021-03-02 青岛科技大学 检测重排酯含量的液相色谱分析方法
CN114195633A (zh) * 2021-12-24 2022-03-18 浙江新和成股份有限公司 一种布洛芬杂质f的合成方法
CN115286501A (zh) * 2022-08-10 2022-11-04 浙江新和成股份有限公司 一种布洛芬结晶母液的综合利用方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2646792C2 (de) * 1975-10-23 1985-05-09 Mitsubishi Petrochemical Co., Ltd., Tokio/Tokyo Verfahren zur Herstellung einer α-(arylsubstituierten)-Propionsäure und/oder eines Esters derselben
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
US4694100A (en) * 1984-07-14 1987-09-15 Nippon Petrochemicals Company, Ltd. Method for producing α-(p-isobutylphenyl)propionic acid or its alkyl esters
JPH064560B2 (ja) * 1986-02-08 1994-01-19 日本石油化学株式会社 ２−（ｐ−イソブチルフエニル）プロピオン酸またはその塩の回収方法
CA1286316C (en) * 1986-02-08 1991-07-16 Isoo Shimizu Method for refining 2-(aryl substituted)-propionic acid or its salt
JPH0657670B2 (ja) * 1986-06-14 1994-08-03 日本石油化学株式会社 粗イブプロフエンの精製方法
US4981995A (en) * 1987-03-20 1991-01-01 Varadaraj Elango Method for producing ibuprofen
DE3802619C1 (de) * 1988-01-29 1989-09-07 Hoechst Ag, 6230 Frankfurt, De
JPH02152945A (ja) * 1988-12-02 1990-06-12 Daicel Chem Ind Ltd ２−（４−ヒドロキシフェノキシ）プロピオン酸エステルの精製法

Also Published As

Publication number Publication date
ES2100212T3 (es) 1997-06-16
US5151551A (en) 1992-09-29
EP0474509A2 (de) 1992-03-11
EP0474509B1 (de) 1997-03-12
MX9100983A (es) 1992-05-04
EP0474509A3 (en) 1993-07-07
ATE149995T1 (de) 1997-03-15
GR3022805T3 (en) 1997-06-30
DK0474509T3 (da) 1997-05-12
CA2050709C (en) 2002-08-20
DE69125073D1 (de) 1997-04-17
BR9103858A (pt) 1992-05-26
CA2050709A1 (en) 1992-03-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition