DE69124844D1 - Radicicol-Derivate, ihre Herstellung und ihre Antitumorwirkung - Google Patents

Radicicol-Derivate, ihre Herstellung und ihre Antitumorwirkung

Info

Publication number
DE69124844D1
DE69124844D1 DE69124844T DE69124844T DE69124844D1 DE 69124844 D1 DE69124844 D1 DE 69124844D1 DE 69124844 T DE69124844 T DE 69124844T DE 69124844 T DE69124844 T DE 69124844T DE 69124844 D1 DE69124844 D1 DE 69124844D1
Authority
DE
Germany
Prior art keywords
production
tumor effects
radicicol derivatives
radicicol
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69124844T
Other languages
English (en)
Inventor
Yukio Sugimura
Kimio Iino
Yoshio Tsujita
Yoko Shimada
Tomowo Kobayashi
Takeshi Kagasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE69124844D1 publication Critical patent/DE69124844D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69124844T 1990-06-06 1991-06-06 Radicicol-Derivate, ihre Herstellung und ihre Antitumorwirkung Expired - Lifetime DE69124844D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14629990 1990-06-06

Publications (1)

Publication Number Publication Date
DE69124844D1 true DE69124844D1 (de) 1997-04-10

Family

ID=15404539

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69124844T Expired - Lifetime DE69124844D1 (de) 1990-06-06 1991-06-06 Radicicol-Derivate, ihre Herstellung und ihre Antitumorwirkung

Country Status (12)

Country Link
US (1) US5597846A (de)
EP (1) EP0460950B1 (de)
KR (1) KR920000763A (de)
CN (1) CN1035381C (de)
AT (1) ATE149498T1 (de)
CA (1) CA2044018A1 (de)
CS (1) CS172591A3 (de)
DE (1) DE69124844D1 (de)
HU (1) HUT60743A (de)
IE (1) IE911915A1 (de)
PT (1) PT97884B (de)
WO (1) WO1991018905A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731343A (en) * 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
AU700840B2 (en) * 1995-04-26 1999-01-14 Kyowa Hakko Kogyo Co. Ltd. Radicicol derivatives
ATE266017T1 (de) 1996-10-25 2004-05-15 Kyowa Hakko Kogyo Kk Radicicolderivate
US6635671B1 (en) 1998-12-24 2003-10-21 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
US6946456B2 (en) * 2000-07-28 2005-09-20 Sloan-Kettering Institute For Cancer Research Methods for treating cell proliferative disorders and viral infections
EP1315732B1 (de) 2000-08-25 2006-06-07 Sloan-Kettering Institute For Cancer Research Radicicol und monocillin und ihre analogen und ihre anwendungen
WO2002094196A2 (en) * 2001-05-23 2002-11-28 Sloan Kettering Institute For Cancer Research Method of treatment for cancers associated with elevated
US20080108694A1 (en) * 2003-12-19 2008-05-08 Samuel J Danishefsky Novel Macrocycles and Uses Thereof
CN103539769B (zh) * 2006-08-11 2016-03-16 斯特拉斯堡大学 用作激酶抑制剂和hsp90抑制剂的大环化合物
WO2009105755A2 (en) 2008-02-21 2009-08-27 Nexgenix Pharmaceuticals Macrocyclic prodrug compounds useful as therapeutics
US20110190237A1 (en) * 2008-01-15 2011-08-04 Nexgenix Pharmaceuticals Macrocyclic Prodrug Compounds Useful as Therapeutics
WO2009132010A1 (en) * 2008-04-21 2009-10-29 Chevron Phillips Chemical Company Lp Methods and systems for making thiol compounds from terminal olefinic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE903997C (de) * 1934-12-08 1954-02-15 Aeg Einrichtung zur UEberwachung von zeitlich in veraenderlicher Staerke geleisteter Arbeit
CH441623A (de) * 1964-05-20 1967-08-15 Sandoz Ag Verfahren zur Herstellung neuer Antibiotica
DE2903997A1 (de) * 1978-02-01 1979-09-06 Grace W R & Co Verfahren zur herstellung von monorden und monordenderivaten
US4166764A (en) * 1978-02-01 1979-09-04 W. R. Grace & Co. Production of monorden
US4228079A (en) * 1978-10-30 1980-10-14 W. R. Grace & Co. Dialkoxy monorden derivatives

Also Published As

Publication number Publication date
US5597846A (en) 1997-01-28
WO1991018905A1 (en) 1991-12-12
CN1035381C (zh) 1997-07-09
CA2044018A1 (en) 1991-12-07
PT97884B (pt) 1998-10-30
PT97884A (pt) 1992-03-31
HUT60743A (en) 1992-10-28
CN1059720A (zh) 1992-03-25
IE911915A1 (en) 1991-12-18
CS172591A3 (en) 1992-04-15
KR920000763A (ko) 1992-01-29
ATE149498T1 (de) 1997-03-15
EP0460950B1 (de) 1997-03-05
HU911893D0 (en) 1991-12-30
EP0460950A1 (de) 1991-12-11

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Legal Events

Date Code Title Description
8332 No legal effect for de