ATE149498T1 - Radicicol-derivate, ihre herstellung und ihre antitumorwirkung - Google Patents

Radicicol-derivate, ihre herstellung und ihre antitumorwirkung

Info

Publication number
ATE149498T1
ATE149498T1 AT91305111T AT91305111T ATE149498T1 AT E149498 T1 ATE149498 T1 AT E149498T1 AT 91305111 T AT91305111 T AT 91305111T AT 91305111 T AT91305111 T AT 91305111T AT E149498 T1 ATE149498 T1 AT E149498T1
Authority
AT
Austria
Prior art keywords
production
antitumor effect
radicicol derivatives
radicicol
derivatives
Prior art date
Application number
AT91305111T
Other languages
English (en)
Inventor
Yukio Sugimura
Kimio Iino
Yoshio Tsujita
Yoko Shimada
Tomowo Kobayashi
Takeshi Kagasaki
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE149498T1 publication Critical patent/ATE149498T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
AT91305111T 1990-06-06 1991-06-06 Radicicol-derivate, ihre herstellung und ihre antitumorwirkung ATE149498T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14629990 1990-06-06

Publications (1)

Publication Number Publication Date
ATE149498T1 true ATE149498T1 (de) 1997-03-15

Family

ID=15404539

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91305111T ATE149498T1 (de) 1990-06-06 1991-06-06 Radicicol-derivate, ihre herstellung und ihre antitumorwirkung

Country Status (12)

Country Link
US (1) US5597846A (de)
EP (1) EP0460950B1 (de)
KR (1) KR920000763A (de)
CN (1) CN1035381C (de)
AT (1) ATE149498T1 (de)
CA (1) CA2044018A1 (de)
CS (1) CS172591A3 (de)
DE (1) DE69124844D1 (de)
HU (1) HUT60743A (de)
IE (1) IE911915A1 (de)
PT (1) PT97884B (de)
WO (1) WO1991018905A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731343A (en) * 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
ES2149468T3 (es) * 1995-04-26 2000-11-01 Kyowa Hakko Kogyo Kk Derivados de radicicol.
WO1998018780A1 (fr) 1996-10-25 1998-05-07 Kyowa Hakko Kogyo Co., Ltd. Derives de radicicol
EP1140069A1 (de) * 1998-12-24 2001-10-10 Novation Pharmaceuticals Inc. Verbindungen, welche die mrna-stabilität beeinflussen, sowie deren medizinische verwendung
KR20030046397A (ko) * 2000-07-28 2003-06-12 슬로안-케테링인스티튜트퍼캔서리서치 세포증식성 질환 및 바이러스 감염의 치료 방법
US7115651B2 (en) 2000-08-25 2006-10-03 Sloan-Kettering Institute For Cancer Research Macrocycles and uses thereof
US7825094B2 (en) * 2001-05-23 2010-11-02 Sloan-Kettering Institute For Cancer Research Method of treatment for cancers associated with elevated HER 2 levels
WO2005061481A1 (en) * 2003-12-19 2005-07-07 Sloan-Kettering Institute For Cancer Research Novel ma crocycles and uses thereof
CN101588799B (zh) * 2006-08-11 2013-09-11 斯特拉斯堡大学 用作激酶抑制剂和hsp90抑制剂的大环化合物
US20110190237A1 (en) * 2008-01-15 2011-08-04 Nexgenix Pharmaceuticals Macrocyclic Prodrug Compounds Useful as Therapeutics
JP5935055B2 (ja) * 2008-02-21 2016-06-15 オンコシナジー・インコーポレイテッド 治療薬として有用な大環状プロドラッグ化合物
WO2009132010A1 (en) * 2008-04-21 2009-10-29 Chevron Phillips Chemical Company Lp Methods and systems for making thiol compounds from terminal olefinic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE903997C (de) * 1934-12-08 1954-02-15 Aeg Einrichtung zur UEberwachung von zeitlich in veraenderlicher Staerke geleisteter Arbeit
CH441623A (de) * 1964-05-20 1967-08-15 Sandoz Ag Verfahren zur Herstellung neuer Antibiotica
US4166764A (en) * 1978-02-01 1979-09-04 W. R. Grace & Co. Production of monorden
DE2903997A1 (de) * 1978-02-01 1979-09-06 Grace W R & Co Verfahren zur herstellung von monorden und monordenderivaten
US4228079A (en) * 1978-10-30 1980-10-14 W. R. Grace & Co. Dialkoxy monorden derivatives

Also Published As

Publication number Publication date
PT97884A (pt) 1992-03-31
US5597846A (en) 1997-01-28
KR920000763A (ko) 1992-01-29
PT97884B (pt) 1998-10-30
CA2044018A1 (en) 1991-12-07
CN1059720A (zh) 1992-03-25
EP0460950B1 (de) 1997-03-05
HUT60743A (en) 1992-10-28
EP0460950A1 (de) 1991-12-11
CS172591A3 (en) 1992-04-15
DE69124844D1 (de) 1997-04-10
CN1035381C (zh) 1997-07-09
IE911915A1 (en) 1991-12-18
WO1991018905A1 (en) 1991-12-12
HU911893D0 (en) 1991-12-30

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