DE69120026D1 - Verfahren zur Leukozytenklassifizierung unter Verwendung der Duchflusszytometrie - Google Patents

Verfahren zur Leukozytenklassifizierung unter Verwendung der Duchflusszytometrie

Info

Publication number
DE69120026D1
DE69120026D1 DE69120026T DE69120026T DE69120026D1 DE 69120026 D1 DE69120026 D1 DE 69120026D1 DE 69120026 T DE69120026 T DE 69120026T DE 69120026 T DE69120026 T DE 69120026T DE 69120026 D1 DE69120026 D1 DE 69120026D1
Authority
DE
Germany
Prior art keywords
procedure
flow cytometry
leukocyte classification
leukocyte
classification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69120026T
Other languages
English (en)
Other versions
DE69120026T2 (de
Inventor
Yasunori Maekawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Publication of DE69120026D1 publication Critical patent/DE69120026D1/de
Application granted granted Critical
Publication of DE69120026T2 publication Critical patent/DE69120026T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69120026T 1990-11-16 1991-11-12 Verfahren zur Leukozytenklassifizierung unter Verwendung der Duchflusszytometrie Expired - Fee Related DE69120026T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2310730A JP2941041B2 (ja) 1990-11-16 1990-11-16 フローサイトメトリーによる白血球の分類方法

Publications (2)

Publication Number Publication Date
DE69120026D1 true DE69120026D1 (de) 1996-07-11
DE69120026T2 DE69120026T2 (de) 1996-11-28

Family

ID=18008791

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120026T Expired - Fee Related DE69120026T2 (de) 1990-11-16 1991-11-12 Verfahren zur Leukozytenklassifizierung unter Verwendung der Duchflusszytometrie

Country Status (5)

Country Link
US (1) US5434081A (de)
EP (1) EP0485945B1 (de)
JP (1) JP2941041B2 (de)
AU (1) AU641566B2 (de)
DE (1) DE69120026T2 (de)

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DE69327775T2 (de) * 1992-11-19 2000-06-21 Sysmex Corp., Kobe Verfahren zur Vorbehandlung für Blutanalyse
AU701948B2 (en) * 1994-10-20 1999-02-11 Sysmex Corporation Reagent for analyzing solid components in urine and method for analyzing solid components by employing the same
US5691204A (en) * 1995-04-21 1997-11-25 Abbott Laboratories Compositions and methods for the rapid analysis of reticulocytes
EP1222451A1 (de) * 1999-10-20 2002-07-17 Becton, Dickinson and Company Vorrichtung und verfahren mit verwendung von nicht-kohärentes licht emittierenden halbleitervorrichtungen als lichtquellen für die teilchendetektion in einem durchflusszytometer
US6813017B1 (en) 1999-10-20 2004-11-02 Becton, Dickinson And Company Apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
AU2001298078A1 (en) * 2000-12-21 2003-09-02 Cerus Corporation Methods for inactivation of pathogens in biological materials
US7547444B1 (en) * 2003-03-03 2009-06-16 Mycosol, Inc. Methods for controlling fungi and bacteria
EP1718966B1 (de) * 2004-02-27 2013-04-24 Beckman Coulter, Inc. Verfahren zum nachweis von malaria und anderen infektionen mit parasiten
JP4509607B2 (ja) * 2004-03-17 2010-07-21 シスメックス株式会社 細胞分析装置および方法
US7264794B2 (en) * 2004-12-17 2007-09-04 The General Hospital Methods of in vivo cytometry
US7491502B2 (en) * 2004-12-17 2009-02-17 The General Hospital Corporation In vivo flow cytometry system and method
US8523882B2 (en) 2005-04-14 2013-09-03 Ethicon Endo-Surgery, Inc. Clip advancer mechanism with alignment features
US7261724B2 (en) * 2005-04-14 2007-08-28 Ethicon Endo-Surgery, Inc. Surgical clip advancement mechanism
US7297149B2 (en) 2005-04-14 2007-11-20 Ethicon Endo-Surgery, Inc. Surgical clip applier methods
US8038686B2 (en) 2005-04-14 2011-10-18 Ethicon Endo-Surgery, Inc. Clip applier configured to prevent clip fallout
US7686820B2 (en) 2005-04-14 2010-03-30 Ethicon Endo-Surgery, Inc. Surgical clip applier ratchet mechanism
US7288098B2 (en) * 2005-04-14 2007-10-30 Ethicon Endo-Surgery, Inc. Force limiting mechanism for medical instrument
US7740641B2 (en) 2005-04-14 2010-06-22 Ethicon Endo-Surgery, Inc. Clip applier with migrational resistance features
JP4745030B2 (ja) * 2005-11-15 2011-08-10 シスメックス株式会社 血液分析装置
JP5032792B2 (ja) * 2006-05-22 2012-09-26 浜松ホトニクス株式会社 細胞選別装置
US20110060232A1 (en) * 2007-05-04 2011-03-10 The General Hospital Corporation Retinal flow cytometry
WO2009120964A2 (en) 2008-03-27 2009-10-01 The General Hospital Corporation In vivo flow cytometry based on cellular autofluorescence
JP5547914B2 (ja) * 2008-08-18 2014-07-16 有限会社 ミクロデント 感染炎症免疫応答計測診断装置
US8267945B2 (en) 2009-10-09 2012-09-18 Ethicon Endo-Surgery, Inc. Clip advancer with lockout mechanism
US8262679B2 (en) 2009-10-09 2012-09-11 Ethicon Endo-Surgery, Inc. Clip advancer
EP2768418B1 (de) 2011-10-19 2017-07-19 Ethicon Endo-Surgery, Inc. Klammerapplikator zur verwendung mit einem chirurgischen roboter
WO2013082029A1 (en) 2011-11-28 2013-06-06 California Institute Of Technology Compositions and methods for leukocyte differential counting
JP6284225B2 (ja) * 2014-03-11 2018-02-28 国立大学法人山口大学 二光子吸収化合物
CN112047876B (zh) * 2020-07-26 2021-07-27 浙江工业大学 红色双光子荧光aie化合物及其合成和应用
CN112362435A (zh) * 2020-11-05 2021-02-12 深圳安侣医学科技有限公司 细胞染色试剂及细胞染色方法
CN113049557A (zh) * 2021-03-12 2021-06-29 广州江元医疗科技有限公司 一种生殖道分泌物多重荧光染色液及其制备方法和应用
CN113959947A (zh) * 2021-10-25 2022-01-21 山东大学 基于二维光散射的单颗粒多模态流式成像检测装置及方法

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US3684377A (en) * 1970-07-13 1972-08-15 Bio Physics Systems Inc Method for analysis of blood by optical analysis of living cells
US4027971A (en) * 1973-01-08 1977-06-07 Philip Kolman Method of simultaneously counting blood cells
US3916205A (en) * 1973-05-31 1975-10-28 Block Engineering Differential counting of leukocytes and other cells
US4345027A (en) * 1980-12-12 1982-08-17 The United States Of America As Represented By The United States Department Of Energy Fluorometric method of quantitative cell mutagenesis
US4637986A (en) * 1983-08-22 1987-01-20 Ortho Diagnostic Systems, Inc. Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
JPS6073356A (ja) * 1983-09-29 1985-04-25 Toa Medical Electronics Co Ltd 血液分析用試薬
US4812394A (en) * 1983-10-18 1989-03-14 University Of California Flow cytomeric measurement of DNA and incorporated nucleoside analogs
US4628026A (en) * 1983-11-15 1986-12-09 Dietlind Gardell Method and apparatus for automated double fluorochromization analysis in lymphocytotoxicity testing
US4902613A (en) * 1984-05-14 1990-02-20 Becton, Dickinson And Company Lysing agent for analysis of peripheral blood cells
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US4727020A (en) * 1985-02-25 1988-02-23 Becton, Dickinson And Company Method for analysis of subpopulations of blood cells
US4978624A (en) * 1985-09-06 1990-12-18 Technicon Instruments Corporation Reagent for the determination of a differential white blood cell count
US4968629A (en) * 1986-08-20 1990-11-06 Hematology Marketing Associates, Inc. Blood diluent for automatic and semi-automatic determination of white cells and method of utilizing same
US5175109A (en) * 1986-09-10 1992-12-29 Toa Medical Electronics Co., Ltd. Reagent for classifying leukocytes by flow cytometry
US5039613A (en) * 1986-11-27 1991-08-13 Toa Medical Electronics Co., Ltd. Reagents used in a method of classifying leukocytes by flow cytometry
US5084378A (en) * 1987-11-30 1992-01-28 The United States Of America As Represented By The United States Department Of Energy Enhanced detection of fluorescence quenching in labeled cells
US4959301A (en) * 1988-04-22 1990-09-25 Massachusetts Institute Of Technology Process for rapidly enumerating viable entities
DE3814811A1 (de) * 1988-05-02 1989-11-16 Merck Patent Gmbh Verfahren und mittel zur differenzierung und bestimmung von leukozyten
US5057413A (en) * 1988-06-13 1991-10-15 Becton, Dickinson And Company Method for discriminating between intact and damaged cells in a sample
JP3098273B2 (ja) * 1991-05-14 2000-10-16 シスメックス株式会社 尿中の細胞分析装置

Also Published As

Publication number Publication date
JPH04184168A (ja) 1992-07-01
JP2941041B2 (ja) 1999-08-25
US5434081A (en) 1995-07-18
AU8774191A (en) 1992-05-21
AU641566B2 (en) 1993-09-23
EP0485945B1 (de) 1996-06-05
EP0485945A3 (en) 1993-02-03
EP0485945A2 (de) 1992-05-20
DE69120026T2 (de) 1996-11-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee