DE69027020T2 - Immunoassay-Verfahren einschliesslich Deaktivierung von endogener alkalischer Phosphatase - Google Patents

Immunoassay-Verfahren einschliesslich Deaktivierung von endogener alkalischer Phosphatase

Info

Publication number
DE69027020T2
DE69027020T2 DE69027020T DE69027020T DE69027020T2 DE 69027020 T2 DE69027020 T2 DE 69027020T2 DE 69027020 T DE69027020 T DE 69027020T DE 69027020 T DE69027020 T DE 69027020T DE 69027020 T2 DE69027020 T2 DE 69027020T2
Authority
DE
Germany
Prior art keywords
alkaline phosphatase
procedures including
endogenous alkaline
immunoassay procedures
including deactivation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69027020T
Other languages
English (en)
Other versions
DE69027020D1 (de
Inventor
Colleen M Nycz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE69027020D1 publication Critical patent/DE69027020D1/de
Publication of DE69027020T2 publication Critical patent/DE69027020T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating And Analyzing Materials By Characteristic Methods (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69027020T 1990-03-01 1990-12-21 Immunoassay-Verfahren einschliesslich Deaktivierung von endogener alkalischer Phosphatase Expired - Fee Related DE69027020T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/486,650 US5279935A (en) 1990-03-01 1990-03-01 Method of immunossay including deactivation of endogenous alkaline phosphatase

Publications (2)

Publication Number Publication Date
DE69027020D1 DE69027020D1 (de) 1996-06-20
DE69027020T2 true DE69027020T2 (de) 1996-10-31

Family

ID=23932730

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69027020T Expired - Fee Related DE69027020T2 (de) 1990-03-01 1990-12-21 Immunoassay-Verfahren einschliesslich Deaktivierung von endogener alkalischer Phosphatase

Country Status (12)

Country Link
US (1) US5279935A (de)
EP (1) EP0444302B1 (de)
JP (1) JPH06105254B2 (de)
AT (1) ATE138201T1 (de)
AU (1) AU625790B2 (de)
CA (1) CA2030649A1 (de)
DE (1) DE69027020T2 (de)
DK (1) DK0444302T3 (de)
ES (1) ES2087118T3 (de)
FI (1) FI911013A (de)
GR (1) GR3020247T3 (de)
IE (1) IE904127A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2023850A1 (en) * 1989-09-28 1991-03-29 Randal A. Hoke Stabilizing reagent for membrane immunoassay
DE69127383T2 (de) * 1990-01-19 1998-03-05 Mina Ltd Gerät und Verfahren zur Untersuchung von Blut und zur Fingerabdruck-Identifikation
ES2123774T3 (es) * 1993-02-17 1999-01-16 Dade Behring Inc Metodo y composicion para la reduccion de la fosfatasa alcalina endogena.
US5516647A (en) * 1993-11-05 1996-05-14 Abbott Laboratories Compounds useful as alkaline phosphatase inhibitors and therapeutic agents
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US5874216A (en) 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
JP4992068B2 (ja) * 2000-01-27 2012-08-08 メディミューン,エルエルシー 超高親和性中和抗体
EP2341075A1 (de) * 2000-03-01 2011-07-06 MedImmune, LLC Anti-rsv-f-protein-antikörper
JP2004500859A (ja) 2000-05-31 2004-01-15 プロメガ コーポレイション キナーゼ及びホスファターゼ用の評価分析法
WO2002010744A1 (fr) * 2000-08-01 2002-02-07 International Reagents Corporation Procede pour pretraiter un echantillon
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
JP3973876B2 (ja) * 2001-10-30 2007-09-12 株式会社三菱化学ヤトロン 新規の細菌分析方法
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
WO2006050166A2 (en) * 2004-10-29 2006-05-11 Medimmune, Inc. Methods of preventing and treating rsv infections and related conditions
EP1978363B1 (de) * 2007-04-03 2010-02-24 Sysmex Corporation Immunassay-Verfahren, Reagenzienkit zur Erkennung einer Alkali-Phosphatase und Reagenzienkit für das Immunassay-Verfahren
JP4830966B2 (ja) * 2007-05-11 2011-12-07 富士レビオ株式会社 不活化アルカリフォスファターゼの製造方法及び酵素免疫測定用の精度向上剤
EP1997830A1 (de) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung
WO2010011860A1 (en) * 2008-07-23 2010-01-28 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
WO2010132447A2 (en) 2009-05-11 2010-11-18 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
WO2011119484A1 (en) 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
JP5716501B2 (ja) * 2011-04-04 2015-05-13 東洋紡株式会社 検体の前処理方法
EP2771349B1 (de) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatikverfahren zur bestimmung von peptidbindungen
EP3418397B1 (de) 2012-01-24 2020-10-07 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
EP3415919B1 (de) 2012-02-07 2020-07-29 Intuitive Biosciences Inc. Für mycobacterium tuberculosis spezifische peptide zur erkennung einer infektion oder immunisierung nichtmenschlicher primaten
US8945827B2 (en) 2013-03-13 2015-02-03 Awareness Technology, Inc. Serological methods and diagnostic tests for syphilis antibodies
CA2983732A1 (en) 2015-04-23 2016-10-27 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Fungal detection using mannan epitope
AU2016301231A1 (en) 2015-08-04 2018-02-22 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (ALTR) necrosis
EP3978619A1 (de) 2015-12-09 2022-04-06 Intuitive Biosciences, Inc. Automatisiertes silberveredelungssystem
WO2017147186A1 (en) 2016-02-22 2017-08-31 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
JP6659406B2 (ja) * 2016-03-04 2020-03-04 田中貴金属工業株式会社 イムノクロマトグラフィー装置
WO2017178554A1 (en) 2016-04-13 2017-10-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1006557B (it) * 1971-09-08 1976-10-20 Bagshawe Kenneth Dawson Cella di reazione particolarmente utile in prove di radioimmunita
US4277560A (en) * 1978-10-24 1981-07-07 Technicon Instruments Corporation Enzyme immunoassays using immobilized reagents in a flowing stream
US4246339A (en) * 1978-11-01 1981-01-20 Millipore Corporation Test device
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4782016A (en) * 1985-01-18 1988-11-01 Eastman Kodak Company Analytical element and method for determination of theophylline by enzyme inhibition
US4656128A (en) * 1985-01-22 1987-04-07 Research Corporation Modified alkaline phosphatase
US4738932A (en) * 1985-12-03 1988-04-19 Advanced Polymer Systems, Inc. Reaginic test for syphilis
JPS62170850A (ja) * 1986-01-23 1987-07-27 Wako Pure Chem Ind Ltd 免疫化学的測定法
US4812293A (en) * 1986-06-30 1989-03-14 Becton, Dickinson And Company Vacuum actuated assay device and method of using same
CA1289876C (en) * 1986-07-15 1991-10-01 Richard R. Anderson Solid phase system incorporating tetrazolium salts for use in ligand-receptor assays
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
IL85018A0 (en) * 1988-01-03 1988-06-30 Orgenics Ltd Stable chromogenic substrate mixture of indoxyl phosphate and tetrazolium salt,method of making and using same in biological and diagnostic assays

Also Published As

Publication number Publication date
JPH06105254B2 (ja) 1994-12-21
ATE138201T1 (de) 1996-06-15
AU625790B2 (en) 1992-07-16
JPH04249768A (ja) 1992-09-04
GR3020247T3 (en) 1996-09-30
FI911013A0 (fi) 1991-02-28
DK0444302T3 (da) 1996-09-02
FI911013A (fi) 1991-09-02
EP0444302A1 (de) 1991-09-04
EP0444302B1 (de) 1996-05-15
AU6701790A (en) 1991-09-05
US5279935A (en) 1994-01-18
DE69027020D1 (de) 1996-06-20
ES2087118T3 (es) 1996-07-16
CA2030649A1 (en) 1991-09-02
IE904127A1 (en) 1991-09-11

Similar Documents

Publication Publication Date Title
DE69027020D1 (de) Immunoassay-Verfahren einschliesslich Deaktivierung von endogener alkalischer Phosphatase
TR24372A (tr) Org.peroksi asit agartma oen-maddelerine dayanan aktivatoer bilesimleri
DE69023951T2 (de) Verfahren zur Herstellung von Kontakten an einer Halbleitervorrichtung.
DE3751420T2 (de) Registrierverfahren und Flüssigkeit unter Verwendung eines wasserlöslichen organischen Lösungsmittels.
ATE236128T1 (de) N-alkylacridancarboxylderivate, geeignet für die detektion von chemilumineszenz
IT7949905A0 (it) Substrato analitico fluorogeno per enzimi proteolitici
DE3789040D1 (de) Wässerige Dispersion von organischen Peroxiden.
DE3781374D1 (de) Fakultatives herausbringen von testmustern.
DE69022255D1 (de) Beta-Lactamasetests mit Gebrauch von chromogenen Niederschlag bildenden Substraten.
DE3789812D1 (de) Poröser wafer zur segmentierten herstellung von bipolymeren.
FI954029A (fi) Kemiluminesoiva reagenssi ja analyysimenetelmä, jossa käytetään substituoitua asetanilidia valon muodostukseen
DK603087D0 (da) Immunokemisk metod tilbestemmelse af stabilt glycosyleret haemoglobin
DE3854209D1 (de) Analyse von organischen Substanzen.
ATE56139T1 (de) Verfahren zur herstellung einer waessrigen pharmazeutischen loesung einer organischen saeure als wirkstoff.
KR900006323A (ko) 시스 3-아미노-4-[2-(2-푸릴)에트-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 말산염.
DE3777934D1 (de) Herstellung von organischen fluessigkeiten.
DE68914108D1 (de) Entwässerung von organischen Sauerstoffverbindungen.
DE3750756D1 (de) Ausführung von Fehlererkennung unter Verwendung eines ungebrauchten Modulo-m-Kodes.
DE3789558D1 (de) Herstellung von organischen Phosphiniten.
DE3875878D1 (de) Mit hoher schnelligkeit betreibbares und zur implementierung als integrierter schaltkreis geeigneter flipflop.
DE69012172D1 (de) Herstellung einer organischen Membrane.
ATE71406T1 (de) Verfahren zur durchfuehrung enzymatischer oxidationen.
KR940004326A (ko) 티록신 또는 트리요오도티로닌의 측정을 위한 방법 및 표준용액
DE3766567D1 (de) Verfahren zur herstellung von alkalimetallbenzolsulfinaten.
DE3761657D1 (de) Verfahren zur herstellung von benzoinsulfonaten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee