DE69024626D1 - Peptidderivate, wertvoll als Antagonisten von Bombesin und Gastrin-freisetzendem Peptid - Google Patents

Peptidderivate, wertvoll als Antagonisten von Bombesin und Gastrin-freisetzendem Peptid

Info

Publication number
DE69024626D1
DE69024626D1 DE69024626T DE69024626T DE69024626D1 DE 69024626 D1 DE69024626 D1 DE 69024626D1 DE 69024626 T DE69024626 T DE 69024626T DE 69024626 T DE69024626 T DE 69024626T DE 69024626 D1 DE69024626 D1 DE 69024626D1
Authority
DE
Germany
Prior art keywords
bombesin
grp
derivatives
antagonists
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69024626T
Other languages
English (en)
Other versions
DE69024626T2 (de
Inventor
Judson V Edwards
Bradford O Fanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69024626D1 publication Critical patent/DE69024626D1/de
Publication of DE69024626T2 publication Critical patent/DE69024626T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57572Gastrin releasing peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086Bombesin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69024626T 1989-11-22 1990-11-22 Peptidderivate, wertvoll als Antagonisten von Bombesin und Gastrin-freisetzendem Peptid Expired - Fee Related DE69024626T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44054789A 1989-11-22 1989-11-22
US60383090A 1990-10-31 1990-10-31

Publications (2)

Publication Number Publication Date
DE69024626D1 true DE69024626D1 (de) 1996-02-15
DE69024626T2 DE69024626T2 (de) 1996-05-15

Family

ID=27032451

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024626T Expired - Fee Related DE69024626T2 (de) 1989-11-22 1990-11-22 Peptidderivate, wertvoll als Antagonisten von Bombesin und Gastrin-freisetzendem Peptid

Country Status (16)

Country Link
EP (1) EP0434979B1 (de)
JP (1) JP2927936B2 (de)
KR (1) KR910009730A (de)
CN (1) CN1051914A (de)
AT (1) ATE132501T1 (de)
AU (1) AU638775B2 (de)
CA (1) CA2030212A1 (de)
DE (1) DE69024626T2 (de)
ES (1) ES2084635T3 (de)
FI (1) FI905741A (de)
HU (1) HUT55798A (de)
IE (1) IE904211A1 (de)
IL (1) IL96402A0 (de)
NO (1) NO905038L (de)
NZ (1) NZ236114A (de)
PT (1) PT95953A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5723578A (en) * 1987-09-24 1998-03-03 The Administrators Of Tulane Educational Fund Peptide analogs of bombesin
US5834433A (en) * 1990-07-26 1998-11-10 Merrell Pharmaceuticals Inc. Compounds and pharmaceutical uses of peptides of bombesin and GRP
JP3350701B2 (ja) * 1991-05-23 2002-11-25 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシン類似体類
JPH07505865A (ja) * 1992-02-07 1995-06-29 メレルダウファーマスーティカルズ インコーポレイテッド ボンベシンのフェニルアラニン類似体類
US5410018A (en) * 1994-02-25 1995-04-25 Oregon Regional Primate Research Center Bombesin-related peptides
IL140845A0 (en) * 1998-07-14 2002-02-10 Corixa Corp Compositions for therapy and diagnosis of prostate cancer
EP2662087A1 (de) 2003-04-22 2013-11-13 Ipsen Pharma Somatostatin-vektoren
CN100372869C (zh) * 2006-04-18 2008-03-05 河北师范大学 棕点湍蛙抗微生物多肽及其在制药中的应用
CN101445554B (zh) * 2008-12-26 2012-06-27 辽宁师范大学 林蛙抗癌肽及其制备方法
CN110133300B (zh) * 2012-03-18 2022-02-25 镜株式会社 疾病样品分析装置、分析系统及分析方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド

Also Published As

Publication number Publication date
AU6679390A (en) 1991-05-30
JP2927936B2 (ja) 1999-07-28
EP0434979A1 (de) 1991-07-03
EP0434979B1 (de) 1996-01-03
PT95953A (pt) 1991-09-13
HUT55798A (en) 1991-06-28
FI905741A0 (fi) 1990-11-21
IE904211A1 (en) 1991-05-22
JPH03261800A (ja) 1991-11-21
IL96402A0 (en) 1991-08-16
AU638775B2 (en) 1993-07-08
KR910009730A (ko) 1991-06-28
NO905038L (no) 1991-05-23
CN1051914A (zh) 1991-06-05
ES2084635T3 (es) 1996-05-16
CA2030212A1 (en) 1991-05-23
HU907234D0 (en) 1991-05-28
DE69024626T2 (de) 1996-05-15
ATE132501T1 (de) 1996-01-15
NO905038D0 (no) 1990-11-21
FI905741A (fi) 1991-05-23
NZ236114A (en) 1993-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee