DE69023992D1 - Festes Matrixsystem zur transdermalen Arzneimittelfreisetzung. - Google Patents

Festes Matrixsystem zur transdermalen Arzneimittelfreisetzung.

Info

Publication number
DE69023992D1
DE69023992D1 DE69023992T DE69023992T DE69023992D1 DE 69023992 D1 DE69023992 D1 DE 69023992D1 DE 69023992 T DE69023992 T DE 69023992T DE 69023992 T DE69023992 T DE 69023992T DE 69023992 D1 DE69023992 D1 DE 69023992D1
Authority
DE
Germany
Prior art keywords
drug release
matrix
transdermal drug
matrix system
fixed matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69023992T
Other languages
English (en)
Other versions
DE69023992T2 (de
Inventor
Chia-Ming Chiang
Renee Ann Tenzel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23604513&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69023992(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cygnus Therapeutic Systems filed Critical Cygnus Therapeutic Systems
Publication of DE69023992D1 publication Critical patent/DE69023992D1/de
Application granted granted Critical
Publication of DE69023992T2 publication Critical patent/DE69023992T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
DE69023992T 1989-09-08 1990-09-03 Festes Matrixsystem zur transdermalen Arzneimittelfreisetzung. Revoked DE69023992T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40563089A 1989-09-08 1989-09-08

Publications (2)

Publication Number Publication Date
DE69023992D1 true DE69023992D1 (de) 1996-01-18
DE69023992T2 DE69023992T2 (de) 1996-04-25

Family

ID=23604513

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69023992T Revoked DE69023992T2 (de) 1989-09-08 1990-09-03 Festes Matrixsystem zur transdermalen Arzneimittelfreisetzung.

Country Status (15)

Country Link
EP (1) EP0416842B1 (de)
JP (3) JP2718433B2 (de)
AT (1) ATE131074T1 (de)
AU (1) AU644815B2 (de)
CA (1) CA2065311C (de)
DE (1) DE69023992T2 (de)
DK (1) DK0416842T3 (de)
ES (1) ES2081352T3 (de)
FI (1) FI107708B (de)
GR (1) GR3019124T3 (de)
IE (1) IE71048B1 (de)
NO (1) NO303262B1 (de)
NZ (1) NZ235068A (de)
PT (1) PT95245B (de)
WO (1) WO1991003219A1 (de)

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US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
US6110488A (en) * 1986-08-28 2000-08-29 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US6117448A (en) * 1986-08-28 2000-09-12 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US5820876A (en) 1986-08-28 1998-10-13 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system
US6139868A (en) * 1986-08-28 2000-10-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US6126963A (en) * 1986-08-28 2000-10-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
USRE37934E1 (en) 1986-08-28 2002-12-10 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5246706A (en) * 1991-07-19 1993-09-21 Cygnus Therapeutic Systems Device for administering bimakalim transdermally
DE4229820C2 (de) * 1992-09-07 1998-12-03 Jenapharm Gmbh Pharmazeutische Zubereitung auf Gestagen-Basis
EP0705097B2 (de) * 1993-06-25 2004-01-14 Alza Corporation Einarbeitung eines poly-n-vinylamids in ein transdermales system
US5460820B1 (en) † 1993-08-03 1999-08-03 Theratech Inc Method for providing testosterone and optionally estrogen replacement therapy to women
US5554381A (en) * 1993-08-09 1996-09-10 Cygnus, Inc. Low flux matrix system for delivering potent drugs transdermally
DE4333595A1 (de) * 1993-10-01 1995-04-06 Labtec Gmbh Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut
GR1002079B (en) * 1994-07-26 1995-12-05 Lavipharm A E System of a special structure and composition for the rapid transdermal administration of oestrogens.
AU3723695A (en) * 1994-09-14 1996-03-29 Minnesota Mining And Manufacturing Company Transdermal device for delivery of levonorgestrel
US5780050A (en) * 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
DE19526864A1 (de) * 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
DE19548332A1 (de) * 1995-12-22 1997-07-10 Rotta Res Bv Hormonpflaster
DE19631084A1 (de) 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
DE19701949A1 (de) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermales therapeutisches System
JP4477152B2 (ja) * 1997-05-16 2010-06-09 株式会社共和 ストーマ用又は瘡傷用の皮膚保護材
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
JP3528739B2 (ja) 2000-02-16 2004-05-24 日産自動車株式会社 エンジンの排気浄化装置
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
CN1198621C (zh) * 2000-11-17 2005-04-27 帝人株式会社 含有雌二醇的贴剂
RU2708563C2 (ru) * 2001-03-16 2019-12-10 Алза Корпорейшн Трансдермальный пластырь для введения фентанила
DE10141652B4 (de) * 2001-08-24 2011-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
JP4194277B2 (ja) 2002-01-25 2008-12-10 久光製薬株式会社 架橋ポリマーを主成分とする粘着性成形体の製造方法
CN101080244B (zh) 2004-12-15 2011-06-08 尼普洛外用药品株式会社 医用贴剂
DE102004062182B4 (de) * 2004-12-20 2007-06-06 Bayer Schering Pharma Ag Transdermales Pflaster mit Progesteron A-Spezifische Liganden (PRASL) als Wirkstoff
ES2536206T3 (es) 2008-02-27 2015-05-21 Hisamitsu Pharmaceutical Co., Inc. Parche medicinal
FR2992325B1 (fr) 2012-06-26 2015-05-22 Ab7 Innovation Matrice sequencee multifonctionnelle monopolymerique en polyurethane coule et procede de fabrication
JP6125547B2 (ja) * 2013-04-24 2017-05-10 あすか製薬株式会社 無定形レボノルゲストレル、固体分散体及びそれらの製造方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632740A (en) * 1968-06-13 1972-01-04 Johnson & Johnson Topical device for the therapeutic management of dermatological lesions with steroids
US3769071A (en) * 1971-06-04 1973-10-30 Minnesota Mining & Mfg Pressure sensitive adhesive tape comprising 5-fluorouracil
US3896789A (en) * 1974-06-10 1975-07-29 Riker Laboratories Inc Retinoic acid dipensing pressure sensitive dermotological tape
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
JPS57142258A (en) * 1981-02-27 1982-09-02 Nitto Electric Ind Co Drug containing tape preparation
JPS57179271A (en) * 1981-04-28 1982-11-04 Sekisui Chem Co Ltd Remedial adhesive tape or sheet
JPS6066759A (ja) * 1983-09-21 1985-04-16 日東電工株式会社 医薬製剤
JPS60123417A (ja) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd 薬物投与部材
GB2156215B (en) * 1984-03-05 1988-03-02 Nitto Electric Ind Co Percutaneous absorption type adhesive pharmaceutical preparation
US4655768A (en) * 1984-07-06 1987-04-07 Avery International Corporation Bandage for sustained delivery of drugs
DE3581188D1 (de) * 1984-07-24 1991-02-07 Key Pharma Klebende schicht zur transdermalen freigabe.
AU563054B2 (en) * 1984-10-24 1987-06-25 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneous tape of isdn
JPS61280426A (ja) * 1985-06-04 1986-12-11 Ikeda Mohandou:Kk 消炎鎮痛用貼付剤
EP0223524B1 (de) * 1985-11-08 1991-10-23 Nitto Denko Corporation Verwendung von Heftpflastern für die Haut und perkutanen Präparaten
US4759816A (en) * 1986-07-07 1988-07-26 Schoeller Technical Papers, Inc. Strippable film for adhesive coating and laminating
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
JP2931002B2 (ja) * 1988-02-26 1999-08-09 ライカー ラボラトリース インコーポレーテッド 皮膚透過エストラジオールデリバリーシステム

Also Published As

Publication number Publication date
GR3019124T3 (en) 1996-05-31
NO920832D0 (no) 1992-03-03
PT95245B (pt) 2001-05-31
JP2000026284A (ja) 2000-01-25
JPH09100227A (ja) 1997-04-15
JPH05500510A (ja) 1993-02-04
FI920960A0 (fi) 1992-03-04
NZ235068A (en) 1993-05-26
NO920832L (no) 1992-03-03
CA2065311C (en) 2000-01-11
WO1991003219A1 (en) 1991-03-21
CA2065311A1 (en) 1991-03-09
PT95245A (pt) 1991-08-14
EP0416842A1 (de) 1991-03-13
DE69023992T2 (de) 1996-04-25
IE71048B1 (en) 1997-01-15
ATE131074T1 (de) 1995-12-15
DK0416842T3 (da) 1996-01-02
AU6441590A (en) 1991-04-08
ES2081352T3 (es) 1996-03-01
EP0416842B1 (de) 1995-12-06
NO303262B1 (no) 1998-06-22
FI107708B (fi) 2001-09-28
IE903259A1 (en) 1991-03-13
JP2718433B2 (ja) 1998-02-25
AU644815B2 (en) 1993-12-23
JP2974969B2 (ja) 1999-11-10

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: CYGNUS, INC., DOVER, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: ORTHO-MCNEIL PHARMACEUTICAL, INC., RARITAN, N.J.,

8328 Change in the person/name/address of the agent

Free format text: BOEHMERT & BOEHMERT, 80336 MUENCHEN

8331 Complete revocation