DE69023682T2 - Gefriergetrocknete Polymerdispersionen und ihre Anwendung zur Darstellung von Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe. - Google Patents

Gefriergetrocknete Polymerdispersionen und ihre Anwendung zur Darstellung von Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe.

Info

Publication number
DE69023682T2
DE69023682T2 DE69023682T DE69023682T DE69023682T2 DE 69023682 T2 DE69023682 T2 DE 69023682T2 DE 69023682 T DE69023682 T DE 69023682T DE 69023682 T DE69023682 T DE 69023682T DE 69023682 T2 DE69023682 T2 DE 69023682T2
Authority
DE
Germany
Prior art keywords
freeze
polymer dispersions
preparation
active ingredients
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69023682T
Other languages
English (en)
Other versions
DE69023682D1 (de
Inventor
Dev K Mehra
Chimanal I Patel
Clayton I Bridges
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FMC Corp
Original Assignee
FMC Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FMC Corp filed Critical FMC Corp
Publication of DE69023682D1 publication Critical patent/DE69023682D1/de
Application granted granted Critical
Publication of DE69023682T2 publication Critical patent/DE69023682T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
DE69023682T 1989-03-23 1990-03-22 Gefriergetrocknete Polymerdispersionen und ihre Anwendung zur Darstellung von Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe. Expired - Fee Related DE69023682T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32793489A 1989-03-23 1989-03-23

Publications (2)

Publication Number Publication Date
DE69023682D1 DE69023682D1 (de) 1996-01-04
DE69023682T2 true DE69023682T2 (de) 1996-04-18

Family

ID=23278720

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69023682T Expired - Fee Related DE69023682T2 (de) 1989-03-23 1990-03-22 Gefriergetrocknete Polymerdispersionen und ihre Anwendung zur Darstellung von Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe.

Country Status (8)

Country Link
US (1) US5326572A (de)
EP (1) EP0388954B1 (de)
AT (1) ATE130511T1 (de)
CA (1) CA2012853A1 (de)
DE (1) DE69023682T2 (de)
DK (1) DK0388954T3 (de)
ES (1) ES2079389T3 (de)
GR (1) GR3018970T3 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
SE9203594D0 (sv) * 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
DE4324474A1 (de) * 1993-07-21 1995-01-26 Henkel Kgaa Verwendung ausgewählter Polyvinylacetat-Dispersionen für die Oberflächenverfestigung von Sand und/oder Erdreich
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
DE4413350A1 (de) 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
DE4423078B4 (de) * 1994-07-01 2005-01-13 Awd.Pharma Gmbh & Co. Kg Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
US5684121A (en) * 1994-12-06 1997-11-04 Isp Investments Inc. N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution
WO1996019200A1 (fr) * 1994-12-19 1996-06-27 Daiichi Pharmaceutical Co., Ltd. Preparation granulaire a liberation prolongee et procede de production
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
US5985313A (en) * 1997-10-22 1999-11-16 New York Blood Center, Inc. Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR101476574B1 (ko) 1999-10-29 2014-12-24 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
US7829148B2 (en) * 2006-02-07 2010-11-09 Fmc Corporation Coating process to produce controlled release coatings
US20070281016A1 (en) * 2006-06-06 2007-12-06 Endo Pharmaceuticals Inc., A Delaware Corporation Sustained release oxycodone composition with acrylic polymer and surfactant
EP2068840A2 (de) * 2006-07-21 2009-06-17 LAB International SRL Hydrophobes missbrauchssicheres ausgabesystem
US9555167B2 (en) * 2006-12-11 2017-01-31 3M Innovative Properties Company Biocompatible antimicrobial compositions
US20080200890A1 (en) * 2006-12-11 2008-08-21 3M Innovative Properties Company Antimicrobial disposable absorbent articles
US11084908B1 (en) 2018-08-31 2021-08-10 Evonik Operations Gmbh Process for preparing a polymer powder
CN114456404B (zh) * 2022-01-24 2024-02-13 哈尔滨工业大学 一种液态金属柔性可穿戴器件及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800463A (en) * 1953-05-14 1957-07-23 Shawinigan Resins Corp Polyvinyl acetate powder and process of making the same
US2809192A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Method of making cellulose esters in the form of small, dense, spherical particles
US3942261A (en) * 1973-12-21 1976-03-09 Toyo Ink Manufacturing Co., Ltd. Method for producing powder paint
US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
AU569277B2 (en) * 1983-03-03 1988-01-28 Dow Chemical Company, The Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents
US4652442A (en) * 1983-07-05 1987-03-24 Arcana Chem. Pharm. Fabrik Gesellschaft M.B.H. Process of producing a sustained release preparation containing indomethacin or niomethacin
BR8806902A (pt) * 1987-04-16 1989-10-31 Christian Bindschaedler Processo para preparacao de um po de polimero insoluvel em agua que pode ser redispersado em uma fase liquida,po resultante e sua utilizacao
US4960814A (en) * 1988-06-13 1990-10-02 Eastman Kodak Company Water-dispersible polymeric compositions

Also Published As

Publication number Publication date
ATE130511T1 (de) 1995-12-15
DE69023682D1 (de) 1996-01-04
EP0388954A3 (de) 1992-09-09
ES2079389T3 (es) 1996-01-16
EP0388954A2 (de) 1990-09-26
EP0388954B1 (de) 1995-11-22
GR3018970T3 (en) 1996-05-31
DK0388954T3 (da) 1995-12-18
CA2012853A1 (en) 1990-09-23
US5326572A (en) 1994-07-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee