ATE130511T1 - Gefriergetrocknete polymerdispersionen und ihre anwendung zur darstellung von arzneimittelzubereitungen mit protrahierter wirkstoffabgabe. - Google Patents

Gefriergetrocknete polymerdispersionen und ihre anwendung zur darstellung von arzneimittelzubereitungen mit protrahierter wirkstoffabgabe.

Info

Publication number
ATE130511T1
ATE130511T1 AT90105437T AT90105437T ATE130511T1 AT E130511 T1 ATE130511 T1 AT E130511T1 AT 90105437 T AT90105437 T AT 90105437T AT 90105437 T AT90105437 T AT 90105437T AT E130511 T1 ATE130511 T1 AT E130511T1
Authority
AT
Austria
Prior art keywords
freeze
polymer dispersions
preparation
application
active ingredients
Prior art date
Application number
AT90105437T
Other languages
English (en)
Inventor
Dev K Mehra
Chimanal I Patel
Clayton I Bridges
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Application granted granted Critical
Publication of ATE130511T1 publication Critical patent/ATE130511T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90105437T 1989-03-23 1990-03-22 Gefriergetrocknete polymerdispersionen und ihre anwendung zur darstellung von arzneimittelzubereitungen mit protrahierter wirkstoffabgabe. ATE130511T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32793489A 1989-03-23 1989-03-23

Publications (1)

Publication Number Publication Date
ATE130511T1 true ATE130511T1 (de) 1995-12-15

Family

ID=23278720

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90105437T ATE130511T1 (de) 1989-03-23 1990-03-22 Gefriergetrocknete polymerdispersionen und ihre anwendung zur darstellung von arzneimittelzubereitungen mit protrahierter wirkstoffabgabe.

Country Status (8)

Country Link
US (1) US5326572A (de)
EP (1) EP0388954B1 (de)
AT (1) ATE130511T1 (de)
CA (1) CA2012853A1 (de)
DE (1) DE69023682T2 (de)
DK (1) DK0388954T3 (de)
ES (1) ES2079389T3 (de)
GR (1) GR3018970T3 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
SE9203594D0 (sv) * 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
IL110014A (en) 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
DE4324474A1 (de) * 1993-07-21 1995-01-26 Henkel Kgaa Verwendung ausgewählter Polyvinylacetat-Dispersionen für die Oberflächenverfestigung von Sand und/oder Erdreich
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
DE4413350A1 (de) 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
DE4423078B4 (de) * 1994-07-01 2005-01-13 Awd.Pharma Gmbh & Co. Kg Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
US5684121A (en) * 1994-12-06 1997-11-04 Isp Investments Inc. N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution
ATE251896T1 (de) * 1994-12-19 2003-11-15 Daiichi Seiyaku Co Granulat-präparate mit kontinuierlicher freisetzung und verfahren zur herstellung
US5985313A (en) * 1997-10-22 1999-11-16 New York Blood Center, Inc. Method for decreasing the frequency of transmission of viral infections using cellulose acetate phthalate or hydroxypropyl methylcellulose phthalate excipients
US6165493A (en) * 1997-10-22 2000-12-26 New York Blood Center, Inc. "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections"
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR100889069B1 (ko) 1999-10-29 2009-03-17 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
BR0115382A (pt) 2000-10-30 2003-09-16 Euro Celtique Sa Formulações para liberação controlada de hidrocodona, método de produzir analgesia efetiva, processo de preparação de uma forma farmacêutica de um sólido oral de liberação controlada, liberação controlada da forma farmacêutica oral e uso da forma farmacêutica
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
US7829148B2 (en) * 2006-02-07 2010-11-09 Fmc Corporation Coating process to produce controlled release coatings
US20070281016A1 (en) * 2006-06-06 2007-12-06 Endo Pharmaceuticals Inc., A Delaware Corporation Sustained release oxycodone composition with acrylic polymer and surfactant
US20080075768A1 (en) * 2006-07-21 2008-03-27 Vaughn Jason M Hydrophobic opioid abuse deterrent delivery system using opioid antagonists
US20080200890A1 (en) * 2006-12-11 2008-08-21 3M Innovative Properties Company Antimicrobial disposable absorbent articles
US9555167B2 (en) * 2006-12-11 2017-01-31 3M Innovative Properties Company Biocompatible antimicrobial compositions
CN112638995B (zh) 2018-08-31 2024-03-19 赢创运营有限公司 制备聚合物粉末的方法
CN114456404B (zh) * 2022-01-24 2024-02-13 哈尔滨工业大学 一种液态金属柔性可穿戴器件及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800463A (en) * 1953-05-14 1957-07-23 Shawinigan Resins Corp Polyvinyl acetate powder and process of making the same
US2809192A (en) * 1954-05-25 1957-10-08 Atlantic Res Corp Method of making cellulose esters in the form of small, dense, spherical particles
US3942261A (en) * 1973-12-21 1976-03-09 Toyo Ink Manufacturing Co., Ltd. Method for producing powder paint
US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
AU569277B2 (en) * 1983-03-03 1988-01-28 Dow Chemical Company, The Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents
US4652442A (en) * 1983-07-05 1987-03-24 Arcana Chem. Pharm. Fabrik Gesellschaft M.B.H. Process of producing a sustained release preparation containing indomethacin or niomethacin
US4968350A (en) * 1987-04-16 1990-11-06 Christian Bindschaedler Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof
US4960814A (en) * 1988-06-13 1990-10-02 Eastman Kodak Company Water-dispersible polymeric compositions

Also Published As

Publication number Publication date
EP0388954A3 (de) 1992-09-09
EP0388954A2 (de) 1990-09-26
DK0388954T3 (da) 1995-12-18
CA2012853A1 (en) 1990-09-23
ES2079389T3 (es) 1996-01-16
US5326572A (en) 1994-07-05
DE69023682T2 (de) 1996-04-18
EP0388954B1 (de) 1995-11-22
DE69023682D1 (de) 1996-01-04
GR3018970T3 (en) 1996-05-31

Similar Documents

Publication Publication Date Title
ATE130511T1 (de) Gefriergetrocknete polymerdispersionen und ihre anwendung zur darstellung von arzneimittelzubereitungen mit protrahierter wirkstoffabgabe.
US5044091B1 (en) Method of preparing a freeze-dried formulation of a drug
EP0158277A3 (de) Implantierbare Zubereitungen von regulatorischen Peptiden mit gesteuerter Freisetzung und Verfahren zur ihrer Herstellung
ATE109000T1 (de) System zur freisetzung von medikamenten und dessen herstellungsmethode.
SE8104661L (sv) Stabil mikrokristallin form av cisplatin, forfarande for framstellning derav samt stabil, steril torrblandningsberedning derav
NO870558D0 (no) Fremgangsmaate for fremstilling av et langsomt frigivende farmasoeytisk preparat.
ATE421318T1 (de) Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben
JP6816015B2 (ja) タンパク質またはペプチド伝達用の溶解性マイクロニドル
ATE72629T1 (de) Cyclosporin enthaltende pharmazeutische zubereitung.
NZ501950A (en) Medicinal compositions for application to mucosa
DE3789965D1 (de) Mikrogranuläre zubereitung zur verabreichung biologisch aktiver stoffe in den eingeweideregionen von tieren.
KR890007789A (ko) 수용성 펩타이드 및 단백질의 생체분해 가능한 마이크로캡슐의 제조방법 및 이 방법에 의해 수득되는 마이크로캡슐
DE3876756D1 (de) Vorrichtung zur gesteuerten freigabe und verabreichung von wirkstoffen an tierisches gewebe.
EP0800828A4 (de) Transmucosale zubereitung
DK1009380T3 (da) Fremgangsmåde til fremstilling af farmaceutiske formuleringer
FR2613223B1 (fr) Forme galenique se presentant sous la forme de grains hydrosolubles, en particulier a base d'un extrait sec de ginkgo biloba, et son procede de preparation
HUP9902032A2 (hu) Peszticid készítmény
ES2018737A6 (es) Composicion plaguicida mejorada y procedimiento para su preparacion.
EP0680763A3 (de) Stabile Präparation zur Behandlung von Störungen der Blutgerinnung, die ein aktiviertes Blutgerinnungsfaktor und Lipidvesikeln enthält
NO912748D0 (no) Fremgangsmaate for fremstilling av vandige blandingsmicelleloesninger.
ATE132877T1 (de) Emulgatorfreie emulsionspolymere in pharmazeutischen zubereitungen mit verzögerter wirkstofffreigabe und ihre herstellung
CA2025315A1 (en) Protein-containing aqueous solutions
ATE111731T1 (de) Pharmazeutische zubereitung zur rektalen verabreichung.
JPS5517326A (en) Creamy drug for external use, and its preparation
JPH0393716A (ja) 可溶性コラーゲンパウダーを担体とする粒状医薬徐放剤の製造方法

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee