DE69019691T2 - Asymmetrische hydrierung von alpha-arylpropensäuren. - Google Patents

Asymmetrische hydrierung von alpha-arylpropensäuren.

Info

Publication number
DE69019691T2
DE69019691T2 DE69019691T DE69019691T DE69019691T2 DE 69019691 T2 DE69019691 T2 DE 69019691T2 DE 69019691 T DE69019691 T DE 69019691T DE 69019691 T DE69019691 T DE 69019691T DE 69019691 T2 DE69019691 T2 DE 69019691T2
Authority
DE
Germany
Prior art keywords
alpha
propenic
acids
alpha aryl
asymmetric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69019691T
Other languages
English (en)
Other versions
DE69019691D1 (de
Inventor
Albert Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/369,875 external-priority patent/US4994607A/en
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of DE69019691D1 publication Critical patent/DE69019691D1/de
Publication of DE69019691T2 publication Critical patent/DE69019691T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0073—Rhodium compounds
    • C07F15/008—Rhodium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
DE69019691T 1989-06-22 1990-06-22 Asymmetrische hydrierung von alpha-arylpropensäuren. Expired - Fee Related DE69019691T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/369,875 US4994607A (en) 1989-06-22 1989-06-22 Asymmetric catalytic hydrogenation of α-arylpropenic acids
US07/487,465 US5202474A (en) 1989-06-22 1990-03-02 Asymmetric catalytic hydrogenation of α-arylpropenoic acids
PCT/US1990/003563 WO1990015790A1 (en) 1989-06-22 1990-06-22 Improved asymmetric catalytic hydrogenation of alpha-arylpropenoic acids

Publications (2)

Publication Number Publication Date
DE69019691D1 DE69019691D1 (de) 1995-06-29
DE69019691T2 true DE69019691T2 (de) 1995-12-21

Family

ID=27004732

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69019691T Expired - Fee Related DE69019691T2 (de) 1989-06-22 1990-06-22 Asymmetrische hydrierung von alpha-arylpropensäuren.

Country Status (11)

Country Link
US (1) US5202474A (de)
EP (2) EP0433424B1 (de)
JP (1) JPH04500370A (de)
AT (1) ATE123014T1 (de)
AU (1) AU633119B2 (de)
CA (1) CA2029882A1 (de)
DE (1) DE69019691T2 (de)
DK (1) DK0433424T3 (de)
ES (1) ES2026438T3 (de)
RU (1) RU2086532C1 (de)
WO (1) WO1990015790A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198561A (en) * 1989-06-22 1993-03-30 Monsanto Company Ruthenium-BINAP asymmetric hydrogenation catalyst
US5233084A (en) * 1989-06-22 1993-08-03 Monsanto Company Method for preparing α-arylpropionic acids
US5935892A (en) * 1994-02-22 1999-08-10 California Institute Of Technology Supported phase catalyst
US5736480A (en) * 1994-02-22 1998-04-07 California Institute Of Technology Supported phase chiral sulfonated BINAP catalyst solubilized in alcohol and method of asymmetric hydrogenation
FR2734823B1 (fr) * 1995-05-29 1997-07-18 Rhone Poulenc Chimie Nouveaux complexes metalliques optiquement actifs et leur utilisation en catalyse asymetrique
JPH11514290A (ja) * 1995-10-13 1999-12-07 カー．ウ．ロイフェン レサーチ エン デフェロプメント 実質的に鏡像異性体として純粋な生成物を得るためのキラルな固形触媒、その製法及びその利用
JPH1059992A (ja) * 1996-08-15 1998-03-03 Takasago Internatl Corp 新規ルテニウム錯体
JP3919268B2 (ja) * 1996-11-08 2007-05-23 高砂香料工業株式会社 ルテニウム−光学活性ホスフィン錯体、その製法およびこれを用いた光学活性４−メチル−２−オキセタノンの製造方法
US6239285B1 (en) 1998-02-06 2001-05-29 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
RU2009126571A (ru) 2006-12-12 2011-01-20 Биал-Портела Энд Ка, С.А. (Pt) Каталитический способ асимметричной гидрогенизации
CN105384623B (zh) * 2015-10-16 2018-01-19 上海交通大学 手性α‑取代丙酸类化合物的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207241A (en) * 1967-01-13 1980-06-10 Syntex Corporation 2-Naphthyl acetic acid derivatives and compositions and methods thereof
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3998966A (en) * 1971-11-04 1976-12-21 Syntex Corporation Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof
US4008281A (en) * 1973-12-03 1977-02-15 Monsanto Company Asymmetric catalysis
SU731892A3 (ru) * 1974-10-15 1980-04-30 Монсанто Компани (Фирма) Способ получени оптических изомеров -замещенных -ациламидопропионовых кислот
IT1110479B (it) * 1978-05-22 1985-12-23 Montedison Spa Processo per la preparazione dell acido 2-(6-metossi-2-naftil)-propionico
IT1109200B (it) * 1979-02-20 1985-12-16 Montedison Spa Processo per la preparazione di esteri di acidi arilacetici da alfa-alo-alchilarilchetoni
US4542237A (en) * 1981-04-30 1985-09-17 Syntex Pharmaceuticals International Limited Manufacture of alpha-arylalkanoic acids and precursors
US4409397A (en) * 1982-05-06 1983-10-11 Shell Oil Company Asymmetric hydrogenation of tetra-substituted olefinic acids and derivatives
JPS5951234A (ja) * 1982-09-16 1984-03-24 Nippon Soda Co Ltd ２−アセチル−６−メトキシナフタレンの製造方法
DE3345660A1 (de) * 1983-12-16 1985-06-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gewinnung von d(+)naproxen
JPS6163690A (ja) * 1984-09-04 1986-04-01 Takasago Corp ルテニウム−ホスフイン錯体
US4601797A (en) * 1984-12-19 1986-07-22 Monsanto Company Electrochemical carboxylation of p-isobutylacetophenone and other aryl ketones
DE3778857D1 (de) * 1986-11-14 1992-06-11 Takasago Perfumery Co Ltd Katalytische produktion von optisch aktiven carbonsaeuren.
JPS63145291A (ja) * 1986-12-09 1988-06-17 Takasago Corp ルテニウム−ホスフイン錯体
JPS63145292A (ja) * 1986-12-09 1988-06-17 Takasago Corp ルテニウム−ホスフイン錯体

Also Published As

Publication number Publication date
DK0433424T3 (da) 1995-10-16
JPH04500370A (ja) 1992-01-23
WO1990015790A1 (en) 1990-12-27
ES2026438T3 (es) 1995-08-01
EP0433424B1 (de) 1995-05-24
ES2026438T1 (es) 1992-05-01
EP0433424A1 (de) 1991-06-26
AU5930690A (en) 1991-01-08
DE69019691D1 (de) 1995-06-29
EP0633238A3 (de) 1995-02-08
AU633119B2 (en) 1993-01-21
ATE123014T1 (de) 1995-06-15
CA2029882A1 (en) 1990-12-23
RU2086532C1 (ru) 1997-08-10
EP0633238A2 (de) 1995-01-11
US5202474A (en) 1993-04-13

Similar Documents

Publication Publication Date Title
ATE125245T1 (de) Verfahren zur herstellung von 3-hydroxyalkanalen.
ATE90931T1 (de) Verfahren zur herstellung von carbonsaeuren.
DE69019691D1 (de) Asymmetrische hydrierung von alpha-arylpropensäuren.
AT380008B (de) Verfahren zur herstellung von mono- oder biscarbonylverbindungen
DE3789098D1 (de) Verfahren zur Nachhydrierung von Sucrose-Polyestern.
DE3869236D1 (de) Verfahren zur herstellung von bariumtitanaten.
DE3770073D1 (de) Katalysator fuer die herstellung von alpha,beta-aethylenisch ungesaettigten monocarboxylsaeuren.
ATE104265T1 (de) Herstellung von 1,1,1-2-tetrafluorethan.
ATE42550T1 (de) Verfahren zur herstellung von tetronsaeure.
ATE46341T1 (de) Verfahren zur herstellung von optisch aktivem 1benzyl-3,4-bis-(diphenylphosphino)-pyrrolidin.
ATE51217T1 (de) Verfahren zur herstellung von nonadecandiolen.
DE3770699D1 (de) Sequentielles doppelkatalysatorverfahren zur herstellung von sorbitol aus hydrolysierter staerkeloesung.
DE69318026D1 (de) Verfahren zur herstellung von phenylterephthalsäure
ATE98623T1 (de) Verfahren zur herstellung von 1,4-butandiol.
ATE59628T1 (de) Verfahren zur herstellung von 2.2.2.trifluor|thanol.
ATE111457T1 (de) Verfahren zur herstellung von di-(p- glycidoxicyclohexyl)-methan.
ATE85612T1 (de) Verbessertes verfahren zur katalytischen hydrierung von dahnp und zur herstellung von dafhp.
DE59008491D1 (de) Verfahren zur herstellung von säurefesten katalysatoren für die direkte hydrierung von carbonsäuren zu alkoholen.
ATE78T1 (de) Verfahren zur herstellung von triphenylphosphin.
ATE100148T1 (de) Verfahren zur herstellung von hochgradig ungesaettigten fettsaeuren.
DE69000265T2 (de) Verfahren zur selektiven hydrogenolyse von perhalogenethanderivaten.
ATE6933T1 (de) Verfahren zur herstellung von 4aminobutters[ureamid.
DE59001237D1 (de) Verfahren zur herstellung von cis-dihydronopol.
ATE73125T1 (de) Verfahren zur herstellung von dialkylaminoethylaminen.
DE59108052D1 (de) Verfahren zur Herstellung von Procain

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee