DE69004214T2 - Arzneimittel mit verzögerter freisetzung und ph-gesteuerten membranüberzügen. - Google Patents
Arzneimittel mit verzögerter freisetzung und ph-gesteuerten membranüberzügen.Info
- Publication number
- DE69004214T2 DE69004214T2 DE90909219T DE69004214T DE69004214T2 DE 69004214 T2 DE69004214 T2 DE 69004214T2 DE 90909219 T DE90909219 T DE 90909219T DE 69004214 T DE69004214 T DE 69004214T DE 69004214 T2 DE69004214 T2 DE 69004214T2
- Authority
- DE
- Germany
- Prior art keywords
- delayed release
- medicinal products
- membrane coatings
- controlled membrane
- coatings
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000003111 delayed effect Effects 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000012528 membrane Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/354,105 US4983401A (en) | 1989-05-22 | 1989-05-22 | Sustained release pharmaceutical preparations having pH controlled membrane coatings |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69004214D1 DE69004214D1 (de) | 1993-12-02 |
DE69004214T2 true DE69004214T2 (de) | 1994-03-03 |
Family
ID=23391895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE90909219T Expired - Fee Related DE69004214T2 (de) | 1989-05-22 | 1990-05-18 | Arzneimittel mit verzögerter freisetzung und ph-gesteuerten membranüberzügen. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4983401A (de) |
EP (1) | EP0425659B1 (de) |
JP (1) | JPH07103015B2 (de) |
AR (1) | AR244089A1 (de) |
DD (1) | DD298350A5 (de) |
DE (1) | DE69004214T2 (de) |
HU (1) | HU215128B (de) |
WO (1) | WO1990014077A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
PH27186A (en) * | 1989-09-07 | 1993-04-16 | Ciba Geigy Ag | Double-coated granules of disodium pamidronate |
IT1246382B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
JP2558396B2 (ja) * | 1990-06-28 | 1996-11-27 | 田辺製薬株式会社 | 放出制御型製剤 |
US5102668A (en) * | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
JP3011752B2 (ja) * | 1990-10-23 | 2000-02-21 | フロイント産業株式会社 | 徐放性製剤およびその製造方法 |
US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
US5656296A (en) * | 1992-04-29 | 1997-08-12 | Warner-Lambert Company | Dual control sustained release drug delivery systems and methods for preparing same |
US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
JP3149125B2 (ja) * | 1995-05-01 | 2001-03-26 | 信越化学工業株式会社 | 固形腸溶製剤のコーティング用基剤 |
US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
US5773031A (en) * | 1996-02-27 | 1998-06-30 | L. Perrigo Company | Acetaminophen sustained-release formulation |
US5656746A (en) * | 1996-03-28 | 1997-08-12 | The Proctor & Gamble Company | Temporary wet strength polymers from oxidized reaction product of polyhydroxy polymer and 1,2-disubstituted carboxylic alkene |
US5698688A (en) * | 1996-03-28 | 1997-12-16 | The Procter & Gamble Company | Aldehyde-modified cellulosic fibers for paper products having high initial wet strength |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US5679559A (en) * | 1996-07-03 | 1997-10-21 | University Of Utah Research Foundation | Cationic polymer and lipoprotein-containing system for gene delivery |
PT946145E (pt) * | 1996-12-20 | 2008-10-17 | Mcneil Ppc Inc | Fármacos antitússicos libertados por resinas de troca iónica |
EP0951278A2 (de) * | 1997-01-03 | 1999-10-27 | ELAN CORPORATION, Plc | Minitablette formulierung zur verzögerte freigabe von cisapride |
PL337799A1 (en) * | 1997-07-01 | 2000-09-11 | Pfizer Prod Inc | Sertralin dosage forms of retarded release |
IL152330A0 (en) | 1997-07-01 | 2003-05-29 | Pfizer | Sertraline salts and sustained-release dosage forms of sertraline |
US6008027A (en) * | 1997-07-17 | 1999-12-28 | Langner; Bruce J. | Enteric polymer coated capsule containing dried bacterial culture for supplying lactase |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
US6126967A (en) * | 1998-09-03 | 2000-10-03 | Ascent Pediatrics | Extended release acetaminophen particles |
JPWO2002034268A1 (ja) * | 2000-10-23 | 2004-03-04 | 小野薬品工業株式会社 | 5−アセチル−4,6−ジメチル−2−[2−[4−(2−メトキシフェニル)ピペラジニル]エチルアミノ]ピリミジン・三塩酸塩を有効成分として含有する徐放性製剤 |
US6663896B1 (en) * | 2001-08-01 | 2003-12-16 | Alvin S. Blum | Delayed release aspirin for vascular obstruction prophylaxis |
US6500454B1 (en) * | 2001-10-04 | 2002-12-31 | Eurand Pharmaceuticals Ltd. | Timed, sustained release systems for propranolol |
US9358214B2 (en) * | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
ES2282492T3 (es) * | 2001-11-30 | 2007-10-16 | Pfizer Products Inc. | Composiciones farmaceuticas de liberacion controlada orales de 5,8,14-triazatetraciclo (10.3.1.0(2,11).0(4,9)-hexadeca-2(11)3,5,7,9-pentaeno. |
US6663888B2 (en) * | 2001-12-14 | 2003-12-16 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
US20050025824A1 (en) * | 2001-12-14 | 2005-02-03 | Eurand Pharmaceuticals Ltd. | Pulsatile release histamine H2 antagonist dosage form |
US20030133982A1 (en) * | 2001-12-20 | 2003-07-17 | Heimlich John M. | Zero-order sustained release dosage forms and method of making same |
GB0203296D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
US7022342B2 (en) | 2002-03-28 | 2006-04-04 | Andrx Corporation, Inc. | Controlled release oral dosage form of beta-adrenergic blocking agents |
US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
US20060003004A1 (en) * | 2002-10-25 | 2006-01-05 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
AU2004207578B2 (en) * | 2003-01-28 | 2007-06-28 | Collegium Pharmaceutical, Inc. | Multiparticulate compositions of milnacipran for oral administration |
US8747895B2 (en) * | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) * | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
CA2584957C (en) | 2004-10-21 | 2015-08-25 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
US20060228487A1 (en) * | 2005-04-11 | 2006-10-12 | J. Rettenmaier & Söehne GmbH + Co. KG | Methods of combining active agents with augmented microcrystalline cellulose |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US7577125B2 (en) | 2005-07-08 | 2009-08-18 | Microsoft Corporation | Direct wireless client to client communication |
US20070141147A1 (en) * | 2005-12-21 | 2007-06-21 | Auriga Laboratories, Inc. | Sequential release pharmaceutical formulations |
JP2009525992A (ja) * | 2006-02-10 | 2009-07-16 | スポーツコム デンマーク アプス | コーティングを施した錠剤、その製造方法、及び関連する使用 |
DE102007026037A1 (de) * | 2007-06-04 | 2008-12-11 | Lts Lohmann Therapie-Systeme Ag | Gastroretentives System mit Alginat-Körper |
EP2406296A1 (de) | 2009-03-09 | 2012-01-18 | Council of Scientific & Industrial Research | Ph-sensitives pfropfcopolymer |
WO2011067667A2 (en) | 2009-12-02 | 2011-06-09 | Eurand Pharmaceuticals Limited | Fexofenadine microcapsules and compositions containing them |
BR112013003331A2 (pt) * | 2010-08-13 | 2017-07-11 | l kraft Daniel | sistemas e métodos para a produção de produtos de fármacos personalizados |
US10265245B2 (en) | 2011-08-27 | 2019-04-23 | Daniel L. Kraft | Portable drug dispenser |
KR102170110B1 (ko) | 2011-12-08 | 2020-10-28 | 알콘 인코포레이티드 | 흡인 및 관주 회로를 위하여 선택적으로 가동 가능한 밸브 요소 |
US9549850B2 (en) | 2013-04-26 | 2017-01-24 | Novartis Ag | Partial venting system for occlusion surge mitigation |
CA3018328A1 (en) | 2014-10-31 | 2016-04-30 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
US11028186B2 (en) | 2016-06-17 | 2021-06-08 | Nec Corporation | Cellulose derivative, cellulose resin composition, molded body and product using same |
US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3091567A (en) * | 1961-02-17 | 1963-05-28 | Nat Starch Chem Corp | Encapsulating agents with controlled water repellency |
US3155590A (en) * | 1962-08-02 | 1964-11-03 | Ncr Co | Encapsulation process and its product |
US3341416A (en) * | 1963-12-11 | 1967-09-12 | Ncr Co | Encapsulation of aspirin in ethylcellulose and its product |
US3531418A (en) * | 1965-08-18 | 1970-09-29 | Ncr Co | En masse encapsulation process |
US3488418A (en) * | 1965-11-18 | 1970-01-06 | Sterling Drug Inc | Sustained relief analgesic composition |
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
BE785702A (fr) * | 1971-07-14 | 1972-10-16 | Roehm Gmbh | Produits de revetement de formes medicamenteuses et leur utilisation |
US4025613A (en) * | 1971-07-19 | 1977-05-24 | Richard G. Powers | Timed-release aspirin |
US3878276A (en) * | 1972-05-24 | 1975-04-15 | Us Interior | Cellulose acetate blend membranes |
DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
JPS53108269A (en) * | 1977-02-09 | 1978-09-20 | Nec Corp | Non hit change-over switch |
CH645391A5 (de) * | 1978-02-21 | 1984-09-28 | Ciba Geigy Ag | Polymere mit succinylobernsteinsaeureester-resten. |
US4205060A (en) * | 1978-12-20 | 1980-05-27 | Pennwalt Corporation | Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use |
JPS5611687A (en) * | 1980-06-02 | 1981-02-05 | Fujitsu Ltd | Semiconductor memory unit |
DE3039073A1 (de) * | 1980-10-16 | 1982-05-19 | Röhm GmbH, 6100 Darmstadt | Umhuelltes acetylsalicylsaeurepraeparat |
US4377481A (en) * | 1980-11-14 | 1983-03-22 | Abcor, Inc. | Blended, polymeric, matrix membrane and process of making and using same |
JPS5867616A (ja) * | 1981-10-15 | 1983-04-22 | Tanabe Seiyaku Co Ltd | 腸溶性マイクロカプセル |
US4663050A (en) * | 1982-01-18 | 1987-05-05 | Standard Oil Company | Semipermeable membranes prepared from polymers containing adjacent, pendent carboxy groups |
JPS62103012A (ja) * | 1985-10-23 | 1987-05-13 | Eisai Co Ltd | 多重顆粒 |
SE460946B (sv) * | 1987-03-16 | 1989-12-11 | Lejus Medical Ab | En multipel-unit-dos komposition av kinidinglukonat |
-
1989
- 1989-05-22 US US07/354,105 patent/US4983401A/en not_active Expired - Fee Related
-
1990
- 1990-05-18 JP JP2508987A patent/JPH07103015B2/ja not_active Expired - Fee Related
- 1990-05-18 WO PCT/US1990/002898 patent/WO1990014077A1/en active IP Right Grant
- 1990-05-18 DE DE90909219T patent/DE69004214T2/de not_active Expired - Fee Related
- 1990-05-18 EP EP90909219A patent/EP0425659B1/de not_active Expired - Lifetime
- 1990-05-18 HU HU904735A patent/HU215128B/hu not_active IP Right Cessation
- 1990-05-22 DD DD90340916A patent/DD298350A5/de unknown
- 1990-05-22 AR AR90316902A patent/AR244089A1/es active
Also Published As
Publication number | Publication date |
---|---|
AR244089A1 (es) | 1993-10-29 |
HUT62784A (en) | 1993-06-28 |
DD298350A5 (de) | 1992-02-20 |
JPH04501428A (ja) | 1992-03-12 |
EP0425659A1 (de) | 1991-05-08 |
JPH07103015B2 (ja) | 1995-11-08 |
WO1990014077A1 (en) | 1990-11-29 |
US4983401A (en) | 1991-01-08 |
HU904735D0 (en) | 1992-04-28 |
EP0425659B1 (de) | 1993-10-27 |
DE69004214D1 (de) | 1993-12-02 |
HU215128B (hu) | 1998-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |