DE68928127D1 - 2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung - Google Patents

2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung

Info

Publication number
DE68928127D1
DE68928127D1 DE68928127T DE68928127T DE68928127D1 DE 68928127 D1 DE68928127 D1 DE 68928127D1 DE 68928127 T DE68928127 T DE 68928127T DE 68928127 T DE68928127 T DE 68928127T DE 68928127 D1 DE68928127 D1 DE 68928127D1
Authority
DE
Germany
Prior art keywords
compounds
stands
methylidene
preparation
nucleoside compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928127T
Other languages
English (en)
Other versions
DE68928127T2 (de
Inventor
Tohru Ueda
Takuma Sasaki
Akira - - - Matsuda
Keiji Yamagami
Akihiro Fujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Welfide Corp
Original Assignee
Yamasa Shoyu KK
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK, Welfide Corp filed Critical Yamasa Shoyu KK
Application granted granted Critical
Publication of DE68928127D1 publication Critical patent/DE68928127D1/de
Publication of DE68928127T2 publication Critical patent/DE68928127T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE68928127T 1988-08-25 1989-08-23 2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung Expired - Fee Related DE68928127T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21206188 1988-08-25

Publications (2)

Publication Number Publication Date
DE68928127D1 true DE68928127D1 (de) 1997-07-17
DE68928127T2 DE68928127T2 (de) 1997-09-25

Family

ID=16616219

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68917060T Expired - Fee Related DE68917060T2 (de) 1988-08-25 1989-08-23 2'-Methylidenpyrimidin-Nukleoside, ihre Verwendung und Verfahren zu ihrer Herstellung.
DE68928127T Expired - Fee Related DE68928127T2 (de) 1988-08-25 1989-08-23 2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE68917060T Expired - Fee Related DE68917060T2 (de) 1988-08-25 1989-08-23 2'-Methylidenpyrimidin-Nukleoside, ihre Verwendung und Verfahren zu ihrer Herstellung.

Country Status (7)

Country Link
US (1) US5705630A (de)
EP (2) EP0566162B1 (de)
KR (1) KR0136869B1 (de)
AT (2) ATE109154T1 (de)
CA (1) CA1319685C (de)
DE (2) DE68917060T2 (de)
ES (1) ES2057031T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9020930D0 (en) * 1990-09-26 1990-11-07 Wellcome Found Pharmaceutical combinations
US5340816A (en) * 1990-10-18 1994-08-23 E. R. Squibb & Sons, Inc. Hydroxymethyl(methylenecyclopentyl) purines and pyrimidines
US5206244A (en) * 1990-10-18 1993-04-27 E. R. Squibb & Sons, Inc. Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
US5665711A (en) * 1995-12-12 1997-09-09 Yoshitomi Pharmaceutical Industries, Ltd. Antitumor composition for oral administration
EP1270008B1 (de) * 2001-05-31 2006-07-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Kondensierte trizyklische Derivate des Guanosins zur Behandlung von Tumoren
KR100481356B1 (ko) * 2002-10-17 2005-04-07 이수화학 주식회사 2'-ｏ-치환된 뉴클레오시드의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE124702T1 (de) * 1987-03-19 1995-07-15 Yamasa Shoyu Kk 2'-alkyliden-pyrimidin-nukleosid-derivate, verfahren zur herstellung und verwendung.

Also Published As

Publication number Publication date
ATE109154T1 (de) 1994-08-15
EP0360018B1 (de) 1994-07-27
KR0136869B1 (ko) 1998-04-25
CA1319685C (en) 1993-06-29
EP0360018A1 (de) 1990-03-28
EP0566162A1 (de) 1993-10-20
DE68917060D1 (de) 1994-09-01
ATE154359T1 (de) 1997-06-15
DE68928127T2 (de) 1997-09-25
ES2057031T3 (es) 1994-10-16
EP0566162B1 (de) 1997-06-11
US5705630A (en) 1998-01-06
DE68917060T2 (de) 1994-12-08
KR900003195A (ko) 1990-03-26

Similar Documents

Publication Publication Date Title
HUT62310A (en) Process for producing pyrimidine nucleoside derivatives and antitumorous pharmaceutical compositions comprising same
ES8603501A1 (es) Un procedimiento para preparar un derivado de 1,8-naftiridina
HUT47128A (en) Process for producing oxetanocins and pharmaceutical compositions comprising such compounds
DE68928127D1 (de) 2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung
EP0289746A3 (en) 1,4-dihydropyridine derivatives and pharmaceutical composition thereof
ES8706610A1 (es) Proceso para preparar un derivado de aminoalcohol.
DE3368050D1 (en) Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them
ATE148128T1 (de) Anthracyclinglycosid-derivate und verfahren zu ihrer herstellung
ATE69448T1 (de) Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
HUT40793A (en) Process for preparing hexene-carboxylic acid derivatives
ES8203917A1 (es) Un procedimiento para la preparacion de un derivado de nu- cleosido de adenina
ES8306733A1 (es) Derivados de anilina y sus sales.
DE68926016D1 (de) Halogeno-4-Methylpyrazole und Verfahren zu ihrer Herstellung
ATE95177T1 (de) Naphthothiazepin-derivate und verfahren zu ihrer herstellung.
EP0312245A3 (de) Polyzyklische Verbindungen und diese enthaltende pharmazeutische Zubereitungen
ES485333A1 (es) Procedimiento para preparar derivados 5,6,7,8-tetrahidro-4 (3h)-quinazolinonicos y sus sales
ES8102115A1 (es) Procedimiento de preparacion de derivados de la xantona
TH4957EX (th) อนุพันธ์ต่าง ๆ ของพิริมิดีน และกรรมวิธีสำหรับการเตรียมสารชนิดเดียวกันนี้

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee