ATE154359T1 - 2'-methylidenpyrimidinnukleosidverbindungen, ihre verwendung und verfahren zu ihrer herstellung - Google Patents

2'-methylidenpyrimidinnukleosidverbindungen, ihre verwendung und verfahren zu ihrer herstellung

Info

Publication number
ATE154359T1
ATE154359T1 AT93109165T AT93109165T ATE154359T1 AT E154359 T1 ATE154359 T1 AT E154359T1 AT 93109165 T AT93109165 T AT 93109165T AT 93109165 T AT93109165 T AT 93109165T AT E154359 T1 ATE154359 T1 AT E154359T1
Authority
AT
Austria
Prior art keywords
compounds
stands
production
nucleoside compounds
methylidenepyrimidine
Prior art date
Application number
AT93109165T
Other languages
English (en)
Inventor
Tohru Ueda
Takuma Sasaki
Akira - - - Kita -Jo Matsuda
Keiji Yamagami
Akihiro Fujii
Original Assignee
Yoshitomi Pharmaceutical
Yamasa Shoyu Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical, Yamasa Shoyu Kk filed Critical Yoshitomi Pharmaceutical
Application granted granted Critical
Publication of ATE154359T1 publication Critical patent/ATE154359T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT93109165T 1988-08-25 1989-08-23 2'-methylidenpyrimidinnukleosidverbindungen, ihre verwendung und verfahren zu ihrer herstellung ATE154359T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21206188 1988-08-25

Publications (1)

Publication Number Publication Date
ATE154359T1 true ATE154359T1 (de) 1997-06-15

Family

ID=16616219

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93109165T ATE154359T1 (de) 1988-08-25 1989-08-23 2'-methylidenpyrimidinnukleosidverbindungen, ihre verwendung und verfahren zu ihrer herstellung
AT89115516T ATE109154T1 (de) 1988-08-25 1989-08-23 2'-methylidenpyrimidin-nukleoside, ihre verwendung und verfahren zu ihrer herstellung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89115516T ATE109154T1 (de) 1988-08-25 1989-08-23 2'-methylidenpyrimidin-nukleoside, ihre verwendung und verfahren zu ihrer herstellung.

Country Status (7)

Country Link
US (1) US5705630A (de)
EP (2) EP0360018B1 (de)
KR (1) KR0136869B1 (de)
AT (2) ATE154359T1 (de)
CA (1) CA1319685C (de)
DE (2) DE68917060T2 (de)
ES (1) ES2057031T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9020930D0 (en) * 1990-09-26 1990-11-07 Wellcome Found Pharmaceutical combinations
US5206244A (en) * 1990-10-18 1993-04-27 E. R. Squibb & Sons, Inc. Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
US5340816A (en) * 1990-10-18 1994-08-23 E. R. Squibb & Sons, Inc. Hydroxymethyl(methylenecyclopentyl) purines and pyrimidines
US5665711A (en) * 1995-12-12 1997-09-09 Yoshitomi Pharmaceutical Industries, Ltd. Antitumor composition for oral administration
EP1270008B1 (de) * 2001-05-31 2006-07-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Kondensierte trizyklische Derivate des Guanosins zur Behandlung von Tumoren
KR100481356B1 (ko) * 2002-10-17 2005-04-07 이수화학 주식회사 2'-ｏ-치환된 뉴클레오시드의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910008800B1 (ko) * 1987-03-19 1991-10-21 야마사 쇼오유 가부시끼가이샤 2'-알킬리덴 피리미딘 누클레오시드 유도체, 그 제조법, 및 그 용도

Also Published As

Publication number Publication date
EP0360018B1 (de) 1994-07-27
CA1319685C (en) 1993-06-29
DE68928127T2 (de) 1997-09-25
ES2057031T3 (es) 1994-10-16
US5705630A (en) 1998-01-06
DE68917060D1 (de) 1994-09-01
DE68917060T2 (de) 1994-12-08
ATE109154T1 (de) 1994-08-15
KR900003195A (ko) 1990-03-26
KR0136869B1 (ko) 1998-04-25
EP0566162A1 (de) 1993-10-20
DE68928127D1 (de) 1997-07-17
EP0360018A1 (de) 1990-03-28
EP0566162B1 (de) 1997-06-11

Similar Documents

Publication Publication Date Title
ATE229527T1 (de) Pyrazolopyridylpyrazinon-derivate und ein verfahren zu ihrer herstellung
DE50001411D1 (de) Tris(oxalato)phosphate, verfahren zu deren herstellung und deren verwendung
ATE164582T1 (de) 1-methylcarbapenemderivate und verfahren zu ihrer herstellung
ATE154359T1 (de) 2'-methylidenpyrimidinnukleosidverbindungen, ihre verwendung und verfahren zu ihrer herstellung
DE3578178D1 (de) Beta-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung.
AU1251988A (en) 1,4-dihydropyridine derivatives and pharmaceutical composition thereof
ATE37872T1 (de) Phenylinden-derivate, ihre salze, und verfahren zu ihrer herstellung.
ES8706610A1 (es) Proceso para preparar un derivado de aminoalcohol.
ATE148128T1 (de) Anthracyclinglycosid-derivate und verfahren zu ihrer herstellung
ATE69448T1 (de) Chinolincarbonsaeure-derivate, diese enthaltende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
HUT40793A (en) Process for preparing hexene-carboxylic acid derivatives
DE68926016D1 (de) Halogeno-4-Methylpyrazole und Verfahren zu ihrer Herstellung
ATE95177T1 (de) Naphthothiazepin-derivate und verfahren zu ihrer herstellung.
EP0312245A3 (de) Polyzyklische Verbindungen und diese enthaltende pharmazeutische Zubereitungen
ES485333A1 (es) Procedimiento para preparar derivados 5,6,7,8-tetrahidro-4 (3h)-quinazolinonicos y sus sales
GB2042540B (en) Process for the preparation of xanthone derivatives

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee