DE68918223D1 - Blutfilter, Verfahren und Vorrichtung für hemorheologische Messungen. - Google Patents

Blutfilter, Verfahren und Vorrichtung für hemorheologische Messungen.

Info

Publication number
DE68918223D1
DE68918223D1 DE68918223T DE68918223T DE68918223D1 DE 68918223 D1 DE68918223 D1 DE 68918223D1 DE 68918223 T DE68918223 T DE 68918223T DE 68918223 T DE68918223 T DE 68918223T DE 68918223 D1 DE68918223 D1 DE 68918223D1
Authority
DE
Germany
Prior art keywords
hemorheological
measurements
blood filter
blood
filter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68918223T
Other languages
English (en)
Other versions
DE68918223T2 (de
Inventor
Kazuo Sato
Yuji Kikuchi
Hiroshi Ohki
Toshio Kaneko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mc Laboratory Inc Tokio/tokyo Jp
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17668775&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68918223(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Application granted granted Critical
Publication of DE68918223D1 publication Critical patent/DE68918223D1/de
Publication of DE68918223T2 publication Critical patent/DE68918223T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/134—Devices using two or more apertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0272—Investigating particle size or size distribution with screening; with classification by filtering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
DE68918223T 1988-11-11 1989-11-07 Blutfilter, Verfahren und Vorrichtung für hemorheologische Messungen. Expired - Lifetime DE68918223T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63283687A JP2685544B2 (ja) 1988-11-11 1988-11-11 血液フィルタおよび血液検査方法並びに血液検査装置

Publications (2)

Publication Number Publication Date
DE68918223D1 true DE68918223D1 (de) 1994-10-20
DE68918223T2 DE68918223T2 (de) 1995-02-02

Family

ID=17668775

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68918223T Expired - Lifetime DE68918223T2 (de) 1988-11-11 1989-11-07 Blutfilter, Verfahren und Vorrichtung für hemorheologische Messungen.

Country Status (4)

Country Link
US (1) US5023054A (de)
EP (1) EP0368241B1 (de)
JP (1) JP2685544B2 (de)
DE (1) DE68918223T2 (de)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7340891A (en) * 1990-02-24 1991-09-18 Hatfield Polytechnic Higher Education Corporation (U.K.) Biorheological measurement
AU1570892A (en) * 1991-03-04 1992-10-06 Kensey Nash Corporation Apparatus and method for determining deformability of red blood cells of a living being
US5376878A (en) * 1991-12-12 1994-12-27 Fisher; Timothy C. Multiple-aperture particle counting sizing and deformability-measuring apparatus
US5458852A (en) * 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
US5885527A (en) * 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6156270A (en) 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6767510B1 (en) * 1992-05-21 2004-07-27 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6905882B2 (en) * 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US7524456B1 (en) 1992-05-21 2009-04-28 Biosite Incorporated Diagnostic devices for the controlled movement of reagents without membranes
US5614093A (en) * 1995-08-23 1997-03-25 Aerojet-General Corporation Discrete pore platelet filter manufactured by electropolishing
US6911183B1 (en) * 1995-09-15 2005-06-28 The Regents Of The University Of Michigan Moving microdroplets
US6136171A (en) * 1998-09-18 2000-10-24 The University Of Utah Research Foundation Micromachined electrical field-flow fractionation system
US6169394B1 (en) * 1998-09-18 2001-01-02 University Of The Utah Research Foundation Electrical detector for micro-analysis systems
JP3258985B2 (ja) 1999-08-09 2002-02-18 独立行政法人 食品総合研究所 白血球活性酸素産生量及び酸化ストレスの測定方法
WO2002026114A2 (en) * 2000-09-27 2002-04-04 Bitensky Mark W Cellular diagnostic arrays, methods of using and processes for producing same
TWI241343B (en) * 2000-12-07 2005-10-11 Effector Cell Inst Inc Well unit for detecting cell chemotaxis and separating chemotactic cells
JP3738899B2 (ja) 2000-12-07 2006-01-25 株式会社 エフェクター細胞研究所 微量試料処理装置
AU2002320576A1 (en) * 2001-07-17 2003-03-03 Paolo Gasparini Microstructure for particle and cell separation, identification, sorting, and manipulation
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
TW200506364A (en) 2003-04-09 2005-02-16 Effector Cell Inst Inc Apparatus for detecting cell chemo-taxis
US7542131B2 (en) * 2003-06-23 2009-06-02 Sewon Meditech, Inc. Apparatus for measuring blood cell deformability
GB0329220D0 (en) * 2003-12-17 2004-01-21 Inverness Medical Switzerland System
US20060051265A1 (en) * 2004-09-08 2006-03-09 Health Research, Inc. Apparatus and method for sorting microstructures in a fluid medium
US20090149345A1 (en) * 2005-03-07 2009-06-11 Kuraray Co., Ltd. Microchannel array and method for producing the same, and blood measuring method employing it
KR100760309B1 (ko) 2005-07-06 2007-10-05 한국과학기술원 미소필터를 이용한 미소입자 변형성 분석기
US7993821B2 (en) 2005-08-11 2011-08-09 University Of Washington Methods and apparatus for the isolation and enrichment of circulating tumor cells
US8173413B2 (en) * 2005-08-11 2012-05-08 University Of Washington Separation and concentration of biological cells and biological particles using a one-dimensional channel
JP2007124904A (ja) * 2005-11-01 2007-05-24 Mc Laboratory Inc 細胞マイクロレオロジー観察・測定用ディスポーザブルチップ
US20090053749A1 (en) * 2006-01-09 2009-02-26 Massachusetts Institute Of Technology Method and Apparatus for High Throughput Diagnosis of Diseased Cells With Microchannel Devices
JP4843794B2 (ja) * 2007-01-15 2011-12-21 国立大学法人山口大学 血液細胞の力学的特性計測システム
US8841135B2 (en) 2007-06-20 2014-09-23 University Of Washington Biochip for high-throughput screening of circulating tumor cells
EP2219020A4 (de) * 2007-11-28 2014-02-05 Konica Minolta Opto Inc System und verfahren zur messung der blutfliessfähigkeit
CN101874201B (zh) * 2007-11-28 2012-08-15 柯尼卡美能达精密光学株式会社 血液流动性测量装置及血液流动性测量方法
CA2722396A1 (en) * 2008-04-23 2009-10-29 Parsortix, Inc. Methods and apparatus for segregation of particles
US8611634B2 (en) 2008-04-30 2013-12-17 Konica Minolta Opto, Inc. Blood aggregation ability measuring apparatus
WO2010007856A1 (ja) * 2008-07-16 2010-01-21 コニカミノルタオプト株式会社 血液特性解析システム
JP5117963B2 (ja) * 2008-09-17 2013-01-16 アークレイ株式会社 分析装置
JP5097658B2 (ja) 2008-09-17 2012-12-12 アークレイ株式会社 流量センサの調整方法
JP5118591B2 (ja) 2008-09-17 2013-01-16 アークレイ株式会社 分析装置
JP5097657B2 (ja) 2008-09-17 2012-12-12 アークレイ株式会社 分析方法
WO2010047191A1 (ja) * 2008-10-24 2010-04-29 コニカミノルタオプト株式会社 血球変形能計測装置
WO2010092727A1 (ja) * 2009-02-16 2010-08-19 コニカミノルタオプト株式会社 血液検査装置
WO2010137470A1 (ja) * 2009-05-29 2010-12-02 コニカミノルタオプト株式会社 変形能計測装置及び変形能計測方法
WO2011010570A1 (ja) * 2009-07-24 2011-01-27 コニカミノルタオプト株式会社 凝集量計測装置及び凝集量計測方法
US20120301867A1 (en) * 2009-09-04 2012-11-29 Kanazawa Medical University Recovering nucleated red blood cells and method for concentrating and recovering nucleated red blood cells
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CN102905522A (zh) 2009-10-12 2013-01-30 新健康科学股份有限公司 用于从红细胞中除去氧的氧消耗装置和方法
US10136635B2 (en) 2010-05-05 2018-11-27 New Health Sciences, Inc. Irradiation of red blood cells and anaerobic storage
NZ622456A (en) 2009-10-12 2015-09-25 New Health Sciences Inc Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
JP5930483B2 (ja) 2010-08-25 2016-06-08 ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 保存中の赤血球の品質及び生存を高める方法
JP5410406B2 (ja) * 2010-12-13 2014-02-05 日本光電工業株式会社 血液測定装置
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
PT4074395T (pt) 2011-08-10 2024-05-20 Hemanext Inc Dispositivo de filtração integrado para depleção de leucócitos, oxigénio e/ou co2 e separação de plasma
PT2768942T (pt) 2011-10-17 2020-01-21 Massachusetts Inst Technology Entrega intracelular
WO2013082273A1 (en) 2011-11-30 2013-06-06 Wellstat Diagnostics, Llc. Filtration module
CN103160430A (zh) * 2011-12-13 2013-06-19 三星电子株式会社 具有高的长宽比的细胞捕获过滤器
KR20130113207A (ko) * 2012-04-05 2013-10-15 삼성전자주식회사 타겟 물질 포획용 필터
KR101404507B1 (ko) * 2012-04-12 2014-06-10 한국과학기술원 다수의 박막 구조물의 조합을 이용한 미소입자 처리 장치
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
PT2852461T (pt) 2012-05-22 2022-09-15 The Administrators Of The Tulane Educational Fund Dispositivos de rede capilar e métodos de utilização
EP3967143A1 (de) 2013-02-28 2022-03-16 Hemanext Inc. Gasanreicherungsvorrichtung zur blutbehandlung und zugehöriges verfahren
PL3033184T3 (pl) 2013-08-16 2021-09-20 Massachusetts Institute Of Technology Selektywne dostarczanie materiału do komórek
US20150290368A1 (en) * 2014-04-09 2015-10-15 Parsortix, Inc. Removal of Particulates from Blood Using an Apparatus Including a Size-Differentiating Element
AU2015338893A1 (en) 2014-10-31 2017-05-04 Massachusetts Institute Of Technology Delivery of biomolecules to immune cells
JP6846345B2 (ja) 2014-11-14 2021-03-24 マサチューセッツ インスティテュート オブ テクノロジー 破壊及び場による細胞への化合物及び組成物の送達
CN107250373A (zh) 2015-01-12 2017-10-13 麻省理工学院 通过微流体递送实现的基因编辑
AU2016228993B2 (en) 2015-03-10 2022-02-10 Hemanext Inc. Oxygen reduction disposable kits, devices and methods of use thereof
CA2983295C (en) 2015-04-23 2024-02-13 New Health Sciences, Inc. Anaerobic blood storage containers
CN107735095B (zh) 2015-05-18 2022-06-14 希玛奈克斯特股份有限公司 储存全血的方法及其组合物
CN107922911A (zh) 2015-07-09 2018-04-17 麻省理工学院 将物质递送至无核细胞
EP3344575B1 (de) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intrazelluläres einbringen von biomolekülen in zellen mit einer zellwand
US10207266B2 (en) 2015-09-29 2019-02-19 Foxconn Interconnect Technology Limited Microfluidic device for detecting cells of blood
ITUA20162939A1 (it) * 2016-04-27 2017-10-27 Nat Systems S R L Dispositivo per rilevare la presenza di particelle di materiale non elettrolita presenti in una soluzione contenente un elettrolita
MX2018014530A (es) 2016-05-27 2019-02-21 New Health Sciences Inc Almacenamiento anaerobico de sangre y metodo de inactivacion de patogenos.
CN106404637B (zh) * 2016-10-08 2018-11-13 重庆医科大学附属永川医院 一种医学检测用血细胞分析仪
FR3058524B1 (fr) * 2016-11-07 2019-01-25 Institut National De La Sante Et De La Recherche Medicale Procede de caracterisation d'un echantillon sanguin
GB2555650B (en) * 2016-11-08 2020-02-12 Univ Salford Imaging apparatus and methods
NL2021386B1 (en) * 2018-07-24 2020-01-30 Stichting Vu Particle volume measurement device, for example flow cytometer, method to determine the compressibility of particles, such as cells, and use of the particle volume measurement device.
KR20210134353A (ko) 2019-02-28 2021-11-09 에스큐지 바이오테크놀로지스 컴퍼니 면역 반응을 변형시키기 위한 pbmc로의 생체분자의 전달
AU2020271040A1 (en) 2019-04-08 2021-11-18 Sqz Biotechnologies Company Cartridge for use in a system for delivery of a payload into a cell

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2982416A (en) * 1957-04-25 1961-05-02 Marvaland Inc Dialysis apparatus
DE3215719C2 (de) * 1982-04-28 1984-01-26 Holger Dr. 5100 Aachen Kiesewetter Meßeinrichtung zur Messung des Verformungsvermögens von roten Blutkörperchen
IL68507A (en) * 1982-05-10 1986-01-31 Univ Bar Ilan System and methods for cell selection
JPS59961U (ja) * 1982-06-25 1984-01-06 東亜医用電子株式会社 血球の特性を測定する装置
US4519244A (en) * 1983-06-21 1985-05-28 Meloy Thomas P Casecadeograph and method of use
US4686041A (en) * 1984-11-26 1987-08-11 Den Berg Teunis T Van Molecular differentiation filter
DE3522186A1 (de) * 1985-06-21 1987-01-02 Hoechst Ag Messeinrichtung zum messen des verformungsvermoegens von roten blutkoerperchen
US4778657A (en) * 1985-09-10 1988-10-18 Kernforschungszentrum Karlsruhe Gmbh Apparatus for determining the characteristics of particles suspended in liquids

Also Published As

Publication number Publication date
DE68918223T2 (de) 1995-02-02
US5023054A (en) 1991-06-11
EP0368241A2 (de) 1990-05-16
JP2685544B2 (ja) 1997-12-03
EP0368241B1 (de) 1994-09-14
EP0368241A3 (en) 1990-09-05
JPH02130471A (ja) 1990-05-18

Similar Documents

Publication Publication Date Title
DE68918223D1 (de) Blutfilter, Verfahren und Vorrichtung für hemorheologische Messungen.
DE3781628D1 (de) Verfahren und vorrichtung zum filtrieren.
DE69017950D1 (de) Verfahren und Vorrichtung zur Sichtbarmachung der Blutströmung.
DE68922874D1 (de) Verfahren und Gerät zur Blutdruckmessung.
DE69021659D1 (de) Verfahren und Vorrichtung zur reihenweisen Parallelprogrammfehlersuche.
DE3877516D1 (de) Geraet und verfahren zur bohrlochmessung.
DE3769344D1 (de) Verfahren zur messung von geruechen und vorrichtung zu diesem zweck.
DE3884498D1 (de) Programmierbares geraet und verfahren zur pruefung eines programmierbaren geraets.
DE3674656D1 (de) Verfahren und vorrichtung zum filtern.
DE69109422D1 (de) Verbessertes Verfahren und Vorrichtung für Sauerstoffanreicherung.
DE3854546D1 (de) Verfahren und Gerät zur Programmablaufmessung.
DE68922727D1 (de) Verfahren und Vorrichtung für die Teilentladungsdetektion.
DE69013790D1 (de) Verfahren und Vorrichtung zur Positionsbestimmung.
ATE102842T1 (de) Vorrichtung und verfahren zum filtrieren.
DE68908879D1 (de) Verfahren und vorrichtung für optische messungen.
DE69215238D1 (de) Vorrichtung und verfahren für die blutfiltration
DE3781313D1 (de) Verfahren und vorrichtung.
DE69020411D1 (de) Verfahren und Gerät für augenoptische Messungen.
DE3888732D1 (de) Verfahren und Vorrichtung für laser-optische Navigation.
DE3781654D1 (de) Verfahren und vorrichtung zur ketonmessung.
DE3884946D1 (de) Verfahren und Vorrichtung zur automatischen Blutdruckmessung.
DE3886243D1 (de) Verfahren und Gerät zur Diagnostik in der Augenheilkunde.
DE3851329D1 (de) Verfahren und vorrichtung zum sammeln von blutmustern.
DE3673917D1 (de) Verfahren und vorrichtung zum absoluten wegmessen.
DE69004297D1 (de) Vorrichtung und Verfahren zum Herstellen von Zigaretten.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MC LABORATORY INC., TOKIO/TOKYO, JP