DE68914869T2 - Verfahren zur stufenweise Oxydation von substituierten 8-Hydroy-chinolinen zu substituierten Pyridin-2,3-dikarbonsäuren. - Google Patents

Verfahren zur stufenweise Oxydation von substituierten 8-Hydroy-chinolinen zu substituierten Pyridin-2,3-dikarbonsäuren.

Info

Publication number
DE68914869T2
DE68914869T2 DE68914869T DE68914869T DE68914869T2 DE 68914869 T2 DE68914869 T2 DE 68914869T2 DE 68914869 T DE68914869 T DE 68914869T DE 68914869 T DE68914869 T DE 68914869T DE 68914869 T2 DE68914869 T2 DE 68914869T2
Authority
DE
Germany
Prior art keywords
substituted
quinolines
hydro
dicarboxylic acids
gradual oxidation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68914869T
Other languages
English (en)
Other versions
DE68914869D1 (de
Inventor
John Joseph Pascavage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DE68914869D1 publication Critical patent/DE68914869D1/de
Publication of DE68914869T2 publication Critical patent/DE68914869T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE68914869T 1988-03-10 1989-02-02 Verfahren zur stufenweise Oxydation von substituierten 8-Hydroy-chinolinen zu substituierten Pyridin-2,3-dikarbonsäuren. Expired - Lifetime DE68914869T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16635988A 1988-03-10 1988-03-10

Publications (2)

Publication Number Publication Date
DE68914869D1 DE68914869D1 (de) 1994-06-01
DE68914869T2 true DE68914869T2 (de) 1994-12-08

Family

ID=22602953

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68914869T Expired - Lifetime DE68914869T2 (de) 1988-03-10 1989-02-02 Verfahren zur stufenweise Oxydation von substituierten 8-Hydroy-chinolinen zu substituierten Pyridin-2,3-dikarbonsäuren.

Country Status (17)

Country Link
EP (1) EP0331899B1 (de)
JP (1) JP2689394B2 (de)
KR (1) KR970011790B1 (de)
CN (1) CN1027813C (de)
AR (1) AR246513A1 (de)
AT (1) ATE104964T1 (de)
AU (1) AU611000B2 (de)
BR (1) BR8901092A (de)
CA (1) CA1327584C (de)
DE (1) DE68914869T2 (de)
DK (1) DK169671B1 (de)
ES (1) ES2063061T3 (de)
HU (1) HU206085B (de)
IE (1) IE64009B1 (de)
IL (1) IL89142A (de)
TW (1) TW198714B (de)
ZA (1) ZA891821B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE109772T1 (de) * 1989-03-22 1994-08-15 American Cyanamid Co Verfahren zur herstellung von substituierten 2,3- pyridindicarbonsäuren durch aufeinanderfolgende oxidation von substituierten chinolinen.
US5281713A (en) * 1991-12-20 1994-01-25 American Cyanamid Company Process for the manufacture of 2-alkoxymethylacrolein
ATE165347T1 (de) * 1993-12-28 1998-05-15 American Cyanamid Co Verfahren zur herstellung pyridin-2,3- dicarboxylicsäure
US5597924A (en) * 1995-05-24 1997-01-28 American Cyanamid Company Coversion of substituted 8-chloroquinolines to substituted 8-hydroxyquinolines
NZ314904A (en) * 1996-06-10 1998-06-26 American Cyanamid Co Preparation of a herbicidal [(5,6-dicarboxy-3-pyridyl)methyl]ammonium halide
CN109225323B (zh) * 2018-10-26 2021-07-27 闽江学院 磺酸基官能化有机/无机双阳离子-钒掺杂杂多酸阴离子复合杂化体及其合成与应用
CN113813895B (zh) * 2021-07-20 2023-03-31 上海罕道医药科技有限公司 一种连续反应装置与一种5-硝基吡啶-3-甲酸的连续制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3771153D1 (de) * 1986-09-12 1991-08-08 American Cyanamid Co Verfahren zur herstellung von pyridin-2,3-dicarboxylsaeuren.

Also Published As

Publication number Publication date
AR246513A1 (es) 1994-08-31
CN1044463A (zh) 1990-08-08
CN1027813C (zh) 1995-03-08
ZA891821B (en) 1989-11-29
TW198714B (de) 1993-01-21
DK169671B1 (da) 1995-01-09
AU3118789A (en) 1989-09-14
JP2689394B2 (ja) 1997-12-10
ES2063061T3 (es) 1995-01-01
CA1327584C (en) 1994-03-08
EP0331899A3 (en) 1990-09-12
EP0331899A2 (de) 1989-09-13
DK114789D0 (da) 1989-03-09
JPH01268677A (ja) 1989-10-26
EP0331899B1 (de) 1994-04-27
KR970011790B1 (ko) 1997-07-16
IL89142A (en) 1993-04-04
HU206085B (en) 1992-08-28
IL89142A0 (en) 1989-09-10
ATE104964T1 (de) 1994-05-15
IE64009B1 (en) 1995-06-28
AU611000B2 (en) 1991-05-30
DK114789A (da) 1989-09-11
IE890764L (en) 1989-09-10
BR8901092A (pt) 1989-10-31
DE68914869D1 (de) 1994-06-01
KR890014487A (ko) 1989-10-24

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