DE68914365T2 - Topische metronidazol-formulationen und deren verwendung als arzneimittel. - Google Patents

Topische metronidazol-formulationen und deren verwendung als arzneimittel.

Info

Publication number
DE68914365T2
DE68914365T2 DE68914365T DE68914365T DE68914365T2 DE 68914365 T2 DE68914365 T2 DE 68914365T2 DE 68914365 T DE68914365 T DE 68914365T DE 68914365 T DE68914365 T DE 68914365T DE 68914365 T2 DE68914365 T2 DE 68914365T2
Authority
DE
Germany
Prior art keywords
medicinal products
topical
topical metronidazole
compositions
metronidazole formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68914365T
Other languages
English (en)
Other versions
DE68914365D1 (de
Inventor
Robert Borgman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma SA
Original Assignee
Galderma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma SA filed Critical Galderma SA
Application granted granted Critical
Publication of DE68914365D1 publication Critical patent/DE68914365D1/de
Publication of DE68914365T2 publication Critical patent/DE68914365T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE68914365T 1988-01-15 1989-01-12 Topische metronidazol-formulationen und deren verwendung als arzneimittel. Expired - Lifetime DE68914365T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/144,252 US4837378A (en) 1986-01-15 1988-01-15 Topical metronidazole formulations and therapeutic uses thereof
PCT/US1989/000116 WO1989006537A1 (en) 1988-01-15 1989-01-12 Topical metronidazole formulations and therapeutic uses thereof

Publications (2)

Publication Number Publication Date
DE68914365D1 DE68914365D1 (de) 1994-05-11
DE68914365T2 true DE68914365T2 (de) 1994-08-11

Family

ID=22507764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68914365T Expired - Lifetime DE68914365T2 (de) 1988-01-15 1989-01-12 Topische metronidazol-formulationen und deren verwendung als arzneimittel.

Country Status (11)

Country Link
US (1) US4837378A (de)
EP (1) EP0355152B1 (de)
JP (1) JP2714464B2 (de)
KR (1) KR0135313B1 (de)
CN (1) CN1032900C (de)
AT (1) ATE103813T1 (de)
AU (1) AU621589B2 (de)
CA (1) CA1297029C (de)
DE (1) DE68914365T2 (de)
WO (1) WO1989006537A1 (de)
ZA (1) ZA89233B (de)

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US5536743A (en) * 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
US5614545A (en) * 1988-06-09 1997-03-25 Leonard Bloom Topical composition for treatment of blepharitis
CA1337279C (en) * 1989-06-06 1995-10-10 Robert J. Borgman Intravaginal treatment of vaginal infections with buffered metronidazole compositions
AU648574B2 (en) * 1990-07-20 1994-04-28 Tillotts Pharma Ag Products and processes for the treatment of the alimentary canal
AU668675B2 (en) * 1990-08-16 1996-05-16 Bloom, Leonard Topical treatment of blepharitis
GB9114346D0 (en) * 1991-07-03 1991-08-21 Dow Corning Sa A method of accelerating drug permeation
US5505948A (en) * 1993-06-01 1996-04-09 Dermatology Home Products, Inc. Home skin peel composition for producing healthy and attractive skin
US5592949A (en) * 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
FR2722098B1 (fr) * 1994-07-06 1996-08-23 Cird Galderma Nouveaux medicaments a base de metro-nidazole ou d'un melange synergetique de metronidazole et de clindamycine
WO1997047300A1 (en) * 1996-06-14 1997-12-18 Stiefel Laboratories, Inc. Antimycotics with metronidazole for treatment of skin disorders
IT1284874B1 (it) 1996-08-02 1998-05-22 Farmigea Spa Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici
WO1999004829A1 (en) * 1997-07-28 1999-02-04 Redmond Mary L Composition and process for the treatment of epidermal traumas such as decubitus ulcers
KR100423686B1 (ko) 1998-01-30 2004-03-18 가부시키가이샤 히타치세이사쿠쇼 고체 물질 용융 장치
US5972993A (en) * 1998-03-20 1999-10-26 Avon Products, Inc. Composition and method for treating rosacea and sensitive skin with free radical scavengers
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Also Published As

Publication number Publication date
CA1297029C (en) 1992-03-10
KR900700099A (ko) 1990-08-11
WO1989006537A1 (en) 1989-07-27
AU621589B2 (en) 1992-03-19
JPH02503004A (ja) 1990-09-20
EP0355152A1 (de) 1990-02-28
JP2714464B2 (ja) 1998-02-16
KR0135313B1 (ko) 1998-04-23
CN1032900C (zh) 1996-10-02
ZA89233B (en) 1990-09-26
AU3043289A (en) 1989-08-11
US4837378A (en) 1989-06-06
EP0355152B1 (de) 1994-04-06
CN1035435A (zh) 1989-09-13
EP0355152A4 (de) 1990-06-27
DE68914365D1 (de) 1994-05-11
ATE103813T1 (de) 1994-04-15

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