DE68912438D1 - Antifungale Antibiotika. - Google Patents

Antifungale Antibiotika.

Info

Publication number
DE68912438D1
DE68912438D1 DE89113184T DE68912438T DE68912438D1 DE 68912438 D1 DE68912438 D1 DE 68912438D1 DE 89113184 T DE89113184 T DE 89113184T DE 68912438 T DE68912438 T DE 68912438T DE 68912438 D1 DE68912438 D1 DE 68912438D1
Authority
DE
Germany
Prior art keywords
alanyl
antifungal antibiotics
antibiotics
compounds
5alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89113184T
Other languages
English (en)
Other versions
DE68912438T2 (de
Inventor
Maki Nishio
Masatoshi Kakushima
Masataka Konishi
Toshikazu Oki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE68912438D1 publication Critical patent/DE68912438D1/de
Publication of DE68912438T2 publication Critical patent/DE68912438T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE68912438T 1988-07-19 1989-07-18 Antifungale Antibiotika. Expired - Fee Related DE68912438T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/221,144 US4960755A (en) 1988-07-19 1988-07-19 BU-3608 derivatives

Publications (2)

Publication Number Publication Date
DE68912438D1 true DE68912438D1 (de) 1994-03-03
DE68912438T2 DE68912438T2 (de) 1994-06-01

Family

ID=22826542

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68912438T Expired - Fee Related DE68912438T2 (de) 1988-07-19 1989-07-18 Antifungale Antibiotika.

Country Status (23)

Country Link
US (1) US4960755A (de)
EP (1) EP0351799B1 (de)
JP (1) JP2772549B2 (de)
KR (1) KR970003127B1 (de)
AT (1) ATE100459T1 (de)
AU (1) AU622197B2 (de)
CA (1) CA1337907C (de)
CS (1) CS274700B2 (de)
DD (2) DD296081A5 (de)
DE (1) DE68912438T2 (de)
DK (1) DK170778B1 (de)
ES (1) ES2048793T3 (de)
FI (1) FI92206C (de)
HU (2) HU205131B (de)
IE (1) IE62586B1 (de)
IL (1) IL91001A (de)
MY (1) MY105128A (de)
NO (1) NO170544C (de)
NZ (1) NZ229964A (de)
PT (1) PT91203B (de)
RU (2) RU2032693C1 (de)
YU (1) YU138289A (de)
ZA (1) ZA895455B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114857A (en) * 1988-11-10 1992-05-19 Bristol-Myers Company Actinomadura hibisca microorganism useful for preparing serine analogs of BU-3608 antibiotics
US5183808A (en) * 1988-11-10 1993-02-02 Bristol-Myers Squibb Company Method for treating fungal infections with serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
US5098708A (en) * 1990-06-14 1992-03-24 Bristol-Myers Squibb Company Antiviral antibiotic BU-3889V
AU634250B2 (en) * 1989-07-10 1993-02-18 Bristol-Myers Squibb Company Antiviral antibiotic bu-3889v
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
CA2030166C (en) * 1989-11-22 1997-10-07 Shimpei Aburaki Pradimicin derivatives
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5338728A (en) * 1992-08-14 1994-08-16 Bristol-Myers Squibb Pradimicin compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics
JP2512050B2 (ja) * 1987-12-25 1996-07-03 財団法人微生物化学研究会 新規抗かび性抗生物質デキシロシルベナノマイシンｂならびにその製造法
US5055453A (en) * 1987-11-02 1991-10-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Benanomicins a and antibiotic compositions
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives

Also Published As

Publication number Publication date
FI92206B (fi) 1994-06-30
EP0351799A2 (de) 1990-01-24
JPH0273095A (ja) 1990-03-13
ES2048793T3 (es) 1994-04-01
KR970003127B1 (ko) 1997-03-14
YU138289A (en) 1991-02-28
DE68912438T2 (de) 1994-06-01
RU2032693C1 (ru) 1995-04-10
NO170544B (no) 1992-07-20
EP0351799A3 (de) 1991-04-24
CS440889A2 (en) 1990-11-14
DD296081A5 (de) 1991-11-21
PT91203B (pt) 1995-03-01
AU622197B2 (en) 1992-04-02
ATE100459T1 (de) 1994-02-15
DK170778B1 (da) 1996-01-15
EP0351799B1 (de) 1994-01-19
IE892325L (en) 1990-01-19
FI893426A (fi) 1990-01-20
MY105128A (en) 1994-08-30
HU205131B (en) 1992-03-30
DK354689A (da) 1990-01-20
NO170544C (no) 1992-10-28
IE62586B1 (en) 1995-02-08
RU2026302C1 (ru) 1995-01-09
FI893426A0 (fi) 1989-07-14
AU3827489A (en) 1990-01-25
ZA895455B (en) 1991-12-24
IL91001A0 (en) 1990-02-09
HUT51283A (en) 1990-04-28
DD287509A5 (de) 1991-02-28
NZ229964A (en) 1991-07-26
JP2772549B2 (ja) 1998-07-02
NO892939D0 (no) 1989-07-18
HU203112B (en) 1991-05-28
CA1337907C (en) 1996-01-09
DK354689D0 (da) 1989-07-18
KR900001715A (ko) 1990-02-27
CS274700B2 (en) 1991-09-15
PT91203A (pt) 1990-02-08
FI92206C (fi) 1994-10-10
IL91001A (en) 1995-06-29
HU908256D0 (en) 1991-06-28
NO892939L (no) 1990-01-22
US4960755A (en) 1990-10-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee